Volumetric MRI changes, cognition and personality traits in old age depression

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Paper (help)
Volumetric MRI changes, cognition and personality traits in old age depression
Authors: Kerstin Weber, Panteleimon Giannakopoulos, Christophe Delaloye, Fabienne de Bilbao, Guenael Moy, Abba Moussa, Montserrat Mendez Rubio, Karsten Ebbing, Reto Meuli, Francois Lazeyras, Corina Meiler-Mititelu, Francois R. Herrmann, Gabriel Gold, Alessandra Canuto
Citation: Journal of affective disorders 124 (3): 275-272. 2010 August
Database(s): PubMed (PMID/20018381)
DOI: 10.1016/j.jad.2009.11.016.
Link(s): http://psychiatrie.hug-ge.ch/recherche_publications/2010weber.pdf
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Volumetric MRI changes, cognition and personality traits in old age depression is a structural magnetic resonance imaging study on human brain region volumes in patients with early-onset depression.

[edit] Subjects

Subject group #1 (help)
Early-onset depressive patients
Subjects/♂/♀: 38 / 7 / 31
Age: 66.11 ±6.22 (–)
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Group 1 of 38 early-onset depressive patients with 7 males and 31 females were included in the study.

The group had a mean age of 66.11.
Subject group #2 (help)
Controls
Subjects/♂/♀: 62 / 14 / 48
Age: 71.10 ±7.36 (–)
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Group 2 of 62 controls with 14 males and 48 females were included in the study. The group had a mean age of 71.10.


[edit] Results

Brain volume results are available for whole brain (Intracranial volume) and total, left and right volumes for the brain regions: hippocampus, amygdala, entorhinal cortex and anterior cingulate cortex. Also hyperintensities are reported for periventricular, deep white matter, basal ganglia and infratentorial (Table 3).

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