Subgenual prefrontal cortex abnormalities in mood disorders

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Subgenual prefrontal cortex abnormalities in mood disorders
Authors: Wayne C. Drevets, Joseph L. Price, Joseph R. Simpson Jr., Richard D. Todd, Theodore Reich, Michael Vannier, Marcus E. Raichle
Citation: Nature 386 (6627): 824-827. 1997 April
Database(s): CiteULike PubMed (PMID/9126739)
DOI: 10.1038/386824a0.
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Subgenual prefrontal cortex abnormalities in mood disorders reports a positron emission tomography and magnetic resonance imaging study on people with depression, both bipolar depression as well as unipolar depression. Special attention is given to the brain region subgenual prefrontal cortex

Contents

[edit] Subject groups

There were several subject groups scanned with difference scanners

  1. Group A, Bipolar depression
  2. Group B, Bipolar depression
  3. Group C, Bipolar depression
  4. Group FPDD, Unipolar depression with familial pure depressive disease (FPDD)
  5. Maniac, Bipolar subjects scanned in the maniac phase

[edit] Results

The are not results from

[edit] Decrease in bipolar depression

Text on page 848, Group A coordinate, Group B statistics

Anatomy
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1 Subgenual prefrontal cortex 5 25 -6 4.3 Brede Database Brede Wiki NeuroSynth SumsDB Not available

[edit] Decrease in epression

Figure 2, Group 3, 4 and 5

Anatomy
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1 Agranular anterior cingulate gyrus -2 32 -2 Brede Database Brede Wiki NeuroSynth SumsDB Not available

[edit] Decrease in bipolar depression

Figure 2, Group A and B (i.e., groups 1 and 2).

This coordinate is not independent from the first experiment.

Anatomy
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x
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1 Agranular anterior cingulate gyrus 1 25 -6 4.3 Brede Database Brede Wiki NeuroSynth SumsDB Not available

[edit] Brain volume results

Figure 3 displays brain volume results for volume of left subgenual prefrontal cortex grey matter. In the text there are several other results.

[edit] Criticism

  1. Figure 3 result is selected among multiple results.

[edit] Related papers

  1. The subgenual anterior cingulate cortex in mood disorders
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