Positron emission tomography

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Positron emission tomography
Abbreviations: PET
Variations:

Positron-Emission Tomography

Category: Positron emission tomography
Parents:

Nuclear imaging

Children:

Positron emission tomography scanner
Brain positron emission tomography

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Positron emission tomography (PET) is an imaging method. It is used in neuroimaging for molecular neuroimaging. PET was also much used for functional neuroimaging activation studies in the 1990's, but now functional magnetic resonance imaging has mostly taken over.

Among the variable in a PET scanning are:

PET scanner maker 
Siemens, CTI, General Electric
PET scanner model 
E.g., 953B-PET
Radiotracer 
O-15 Water
Radioisotope 
E.g., Oxygen-15
Delivery method 
E.g., Bolus infusion
Amount delivered 
E.g. Becquerel or Concentration with flow rate and duration of infusion.
Duration of scanning 
E.g., two minutes.
Scanner mode 
Dynamic, integrated counts
Laboratory of experiment 
The PET scanning lab.
Number of slices 
Number of tomographic slices
Reconstruction filter 
E.g. Hanning 8.5 mm
Axial field of view 
E.g., 15.2 cm
Variable 
Physical variable measured, e.g., "CBF", "binding potential"

[edit] Dynamic PET

The analysis of dynamic PET may rely on input curve estimation from independent component analysis[1] or clustering.[2]

[edit] References

  1. Jae Sung Lee, Dong Soo Lee, Ji Young Ahn, Gi Jeong Cheon, Seok-Ki Kim, Jeong Seok Yeo, Kangjun Seo, Kwang Suk Park, June-Key Chung, Myung Chul Lee (2001). "Blind separation of cardiac components and extraction of input function from H(2)(15)O dynamic myocardial PET using independent component analysis". The Journal of Nuclear Medicine 42(6): 938-943. PMID: 11390560. [1].
  2. Matthew Liptrot, Karen H. Adams, Lars Martiny, Lars H. Pinborg, Markus N. Lonsdale, Niels V. Olsen, Søren Holm, Claus Svarer, Gitte Moos Knudsen (2004). "Cluster analysis in kinetic modelling of the brain: a noninvasive alternative to arterial sampling". NeuroImage 21(2): 483-493. doi: 10.1016/j.neuroimage.2003.09.058.
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