No evidence for an association between the BDNF val66met polymorphism and schizophrenia or personality traits

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Paper (help)
No evidence for an association between the BDNF val66met polymorphism and schizophrenia or personality traits
Authors: Mamoru Tochigi, Takeshi Otowa, Motomu Suga, Mark Rogers, Takanobu Minato, Hidenori Yamasue, Kiyoto Kasai, Nobumasa Kato, Tsukasa Sasaki
Citation: Schizophrenia Research 87 (1-3): 45-47. 2006 October
Database(s): PubMed (PMID/16854566)
DOI: 10.1016/j.schres.2006.06.029.
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Extract:

No evidence for an association between the BDNF val66met polymorphism and schizophrenia or personality traits report a schizophrenia genetics association study and personality genetics study on the val66met BDNF gene genetic polymorphism. Personality traits were assessed with the NEO PI-R and STAI.

[edit] Subjects

Subject group #1 (help)
Japanese schizophrenics
Subjects/♂/♀: 401 /  /
Age: (–)
Nationality: Japanese
Approval: Ethical Committee of the Faculty of Medicine, University of Tokyo
Databases:

Group 1 of 401 japanese schizophrenics were included in the study.

The study on the human subjects was approved by the Ethical Committee of the Faculty of Medicine, University of Tokyo.
Subject group #2 (help)
Healthy Japanese
Subjects/♂/♀: 569 / 254 / 315
Age: 35.6 ±11.5 (–)
Nationality: Japanese
Approval: Ethical Committee of the Faculty of Medicine, University of Tokyo
Databases:

Group 2 of 569 healthy Japanese with 254 males and 315 females were included in the study. The Japanese group had a mean age of 35.6. The study on the human subjects was approved by the Ethical Committee of the Faculty of Medicine, University of Tokyo. The personality traits were assessed on the healthy Japanese group.

[edit] Results

Personality genetics results are not shown.

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