Amygdala volume in major depressive disorder: a meta-analysis of magnetic resonance imaging studies

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Amygdala volume in major depressive disorder: a meta-analysis of magnetic resonance imaging studies
Authors: J. Paul Hamilton, Matthias Siemer, Ian H. Gotlib
Citation: Molecular Psychiatry 13 (11): 993-1000. 2008 November
Database(s): PubMed (PMID/18504424)
DOI: 10.1038/mp.2008.57.
PMCID:2739676
Link(s): http://mood.stanford.edu/gotlib_pdfs/hamilton_seimer_gotlib_2008.pdf
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Amygdala volume in major depressive disorder: a meta-analysis of magnetic resonance imaging studies is a meta-analysis of the volume of amygdala in patients with major depressive disorder.

[edit] Included studies

13 studies were included in the meta-analysis (Frodl listed twice!)

  1. Hastings, Volumetric analysis of the prefrontal cortex, amygdala, and hippocampus in major depression
  2. von Gunten, A volumetric study of hippocampus and amygdala in depressed patients with subjective memory problems
  3. Caetano, Anatomical MRI study of hippocampus and amygdala in patients with current and remitted major depression
  4. Hickie, Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression
  5. Monkul, Fronto-limbic brain structures in suicidal and non-suicidal female patients with major depressive disorder
  6. Sheline, Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression
  7. Sheline, Amygdala core nuclei volumes are decreased in recurrent major depression
  8. Frodl, Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects
  9. Munn, Amygdala volume analysis in female twins with major depression
  10. Lange and Irle, Enlarged amygdala volume and reduced hippocampal volume in young women with major depression
  11. Weniger, Abnormal size of the amygdala predicts impaired emotional memory in major depressive disorder
  12. Frodl, Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects
  13. Bremner, Hippocampal volume reduction in major depression

[edit] Related studies

  1. Structural neuroimaging studies in major depressive disorder: meta-analysis and comparison with bipolar disorder
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