A PET 18F altanserin study of 5-HT2A receptor binding in the human brain and responses to painful heat stimulation

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Paper (help)
A PET 18F altanserin study of 5-HT2A receptor binding in the human brain and responses to painful heat stimulation
Authors: Ron C. Kupers, Vibe Gedsø Frøkjær, Arne Naert, Rune Christensen, Esben Budtz-Jørgensen, Henrik Kehlet, Gitte Moos Knudsen
Citation: NeuroImage 44 : 1001-1007. 2009
Database(s): PubMed (PMID/19007894)
DOI: 10.1016/j.neuroimage.2008.10.011.
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A PET [18F] altanserin study of 5-HT2A receptor binding in the human brain and responses to painful heat stimulation reports a positron emission tomography study with altanserin used as a radioligand.


[edit] Subjects

Subject group (help)
Healthy controls
Subjects/♂/♀: 18 /  /
Age: 32.2 ±8.9 (–)
Nationality: Danish
Approval: define approval
Databases:

A group of 18 healthy controls were included in the study. The Danish group had a mean age of 32.2.

There were originally 21 scanned (12 males, 9 females), however 3 subjects were not included for the final result, due to different reasons.

The subject group overlap with previous studies from the research group.

[edit] Results

Eight coordinates in Table 3.

These coordinates are peak coordinates for correlation with participants rating in the tonic pain condition.

Anatomy
BA
x
y
z
No. vox
t
z
Coordinate search
Plot
1 Superior parietal lobule 7 28 -72 50 6118 3.81 Brede Database Brede Wiki NeuroSynth SumsDB Not available
2 Posterior cingulate cortex 23 16 -44 44 162 3.30 Brede Database Brede Wiki NeuroSynth SumsDB Not available
3 Inferior parietal lobule 40 -40 -44 44 210 3.07 Brede Database Brede Wiki NeuroSynth SumsDB Not available
4 Gyrus orbitalis 11 16 40 -24 344 3.03 Brede Database Brede Wiki NeuroSynth SumsDB Not available
5 Gyris frontalis medius 9 32 18 36 278 2.96 Brede Database Brede Wiki NeuroSynth SumsDB Not available
6 Gyris frontalis medius 10 -32 48 4 398 2.95 Brede Database Brede Wiki NeuroSynth SumsDB Not available
7 Precentral gyrus 4 -48 -10 44 324 2.83 Brede Database Brede Wiki NeuroSynth SumsDB Not available
8 Precentral gyrus 4 42 -12 46 54 2.63 Brede Database Brede Wiki NeuroSynth SumsDB Not available
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