15th Annual Meeting of the Organization for Human Brain Mapping
|15th Annual Meeting of the Organization for Human Brain Mapping (HBM2009)|
|Location:||San Francisco California United States of America Map|
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15th Annual Meeting of the Organization for Human Brain Mapping took place 2009 June 18-23 in San Francisco at the San Francisco Marriott at 55 Fourth Street.
Over 2200 posters was displayed with abstracts available online at
The conference was split between a Talairach Lecture, keynote lectures (e.g., with Robert Zatorre), morning workshops, oral and poster sessions, exhibits, symposia including a local organizing committee symposium and educational courses.
 Morning workshops
Three parallel workshops ran on all four days.
- Imaging genomics chaired by David C. Glahn and with entries from, e.g., Thomas E. Nichols and Vince Calhoun.
- Neurocognitive ontologies. Organized by Maryann E. Martone and with entries from, e.g., BIRNLex (NeuroLex), Neural Electromagnetic Ontologies (NEMO).
- Reproducibility and reliability. Chair: Stephen C. Strother . With entries from Stephen Strother (about NPAIRS), Morgan Hough (about Genovese's binomial mixure mode), Gregory Brown (reproducibility across multisite scannings of the same subjects) and Michelle Liou.
- Pittsburgh Brain Connectivity Competition 2009: Mapping the Human Connectome
 Educational courses
 Imaging genetics
Hao-Yang Tan talked about:
- Working memory dysfunction and schizophrenia with interacting dopaminergic gene: DAT, GRM3 and AKT1.
- Meta-analysis on COMT by Mier (2009) in Molecular Psychiatry: Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis.
- U-curve with amphetamine on working memory prefrontal cortical activation Mattay in PNAS 2004
Nelson Freimer talked among other issues about
- Significance thresholds for linkage: Lander and Kruglyak 1996.
- HVA gene in vervet monkey with linkage analysis.
- Posterior odds = (Prior odds x Power) / Significance.
- Did a meta-analysis of on the serotonin transporter gene — also for personality.
- Genomewide association analysis (some of the best): HDL association at 16q22.1. Very very low p-values.
- A success story in neuropsychiatry: Narcolepsy (Emmanuel Mignot): T-cell receptor alpha locus. J. Hallmayer, Nature Genetics, 41, 2009.
Freimer talked well for genomewide association analyses. Whole genome sequencing is coming, — but there is no very good models for them. He do not think much of candidate gene analysis.
Jean-Baptiste Poline talked about databases for managing large cohort imaging genetics studies:
- "Excel will kill you"
- BrainMap, BIRN, ADNI (http://www.adni-info.org/), XNAT (probably the most mature).
- Remote computing, reproducibility, provenance.
- Saguenay Youth Study: Saguenay-Lac-Saint-Jean (a Canadian locality) done by Tomas Paus
- Imagen study. European study. Scito, NNL. Use the XNAT to store the data.