WOROI: 150 - Hypothalamus
 
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WOROI: 150 - Hypothalamus

Abbreviation: Hy

External databases

MeSH UID: D007031
BrainInfo: 358
IBVD: Hypothalamus
Wikipedia: Hypothalamus

Taxonomy

ParentsSiblingsChildren
Diencephalon
  Hypophysis
Mamillary bodies
Posterior hypothalamus
Left hypothalamus
Right hypothalamus

Talairach coordinates

  x     y     z   Lobar anatomy WOBIB WOEXP
-4 -5 -12 Left hypothalamus 4 9
1 -9 -6 Hypothalamus 62 193
-6 -8 -3 Hypothalamus 93 294
-2 -10 -6 Hypothalamus 93 295
-3 -20 5 Bilaterally in the hypothalamus and the central grey of the midbrain 99 310
-10 -2 4 Ventral striatum, nucleus accumbens, anterior thalamus, ventral tegmentum area, hypothalamus, amygdala 111 342
-2 -17 8 Left hypothalamus 137 424
0 -8 -10 Hypothalamus 161 493
-6 -4 0 Hypothalamus 177 540
6 -12 -8 Hypothalamus 177 541
4 -6 -8 Hypothalamus 177 544
0 -12 -4 Hypothalamus 177 547

Summary

  x     y     z   Description
-5 -9 -1 Mean coordinate in left hemisphere
4 -9 -7 Mean coordinate in right hemisphere
4 -9 -3 Mean coordinate with ignored left/right
0 -20 -12 Minimum coordinate with ignored left/right
10 -2 8 Maximum coordinate with ignored left/right
3 5 6 Standard deviation with ignored left/right
corner cube of WOROI: 150 - Hypothalamus

Text contexts

Only for the group of male subjects was there evidence of a significant activation of the thalamus and hypothalamus, a sexually dimorphic area of the brain known to play a pivotal role in physiological arousal and sexual behaviorSherif Karama; Andre R. Lecours; Jean-Maxime Leroux; Pierre Bourgouin; Gilles Beaudoin; Sven Joubert; Mario Beauregard. Areas of brain activation in males and females during viewing of erotic film excerpts. Human Brain Mapping 16(1):1-13, 2002. PMID: 11870922. WOBIB: 4.
They further suggest that the greater SA generally experienced by men, when viewing erotica, may be related to the functional gender difference found here with respect to the hypothalamusSherif Karama; Andre R. Lecours; Jean-Maxime Leroux; Pierre Bourgouin; Gilles Beaudoin; Sven Joubert; Mario Beauregard. Areas of brain activation in males and females during viewing of erotic film excerpts. Human Brain Mapping 16(1):1-13, 2002. PMID: 11870922. WOBIB: 4.
Comparing baseline scans during pain with scans taken after stimulation, when the patient had become pain-free, revealed significant rCBF increases in the prefrontal (Brodmann areas (BA) 9, 10, 11 and 47) and anterior insular cortices, hypothalamus and periaqueductal gray associated with the presence of chronic painR. C. Kupers; J. M. Gybels; Albert Gjedde. Positron emission tomography study of a chronic pain patient successfully treated with somatosensory thalamic stimulation. Pain 87(3):295-302, 2000. PMID: 10963909. WOBIB: 62.
Pleasant and unpleasant emotions were each distinguished from neutral emotion conditions by significantly increased cerebral blood flow in the vicinity of the medial prefrontal cortex (Brodmann's area 9), thalamus, hypothalamus and midbrain (P < 0Richard D. Lane; Eric M. Reiman; M. M. Bradley; P. J. Lang; Geoffrey L. Ahern; Richard J. Davidson; Gary E. Schwartz. Neuroanatomical correlates of pleasant and unpleasant emotion. Neuropsychologia 35(11):1437-44, 1997. PMID: 9352521. BrainMap: 276. WOBIB: 93.
Subcortically, conditioning increased rCBF bilaterally in the ventromedial thalamus, the posterior hypothalamus and the central grey of the midbrainM. Fredrikson; G. Wik; Hċkan Fischer; J. Andersson. Affective and attentive neural networks in humans: a PET study of Pavlovian conditioning. NeuroReport 7(1):97-101, 1995. PMID: 8742426. WOBIB: 99.
Findings from functional imaging studies have shown activation of the brainstem during migraine without aura (MWOA) and activation of the hypothalamus during cluster headacheA. Bahra; M. S. Matharu; Christian Büchel; Richard S. J. Frackowiak; P. J. Goadsby. Brainstem activation specific to migraine headache. Lancet 357(9261):1016-7, 2001. PMID: 11293599. WOBIB: 122.
Activation in the hypothalamus was seen solely in the pain state and was not seen in patients who have cluster headache but were out of the boutArne May; Anish Bahra; Christian Büchel; Richard S. J. Frackowiak; Peter J. Goadsby. Hypothalamic activation in cluster headache attacks. Lancet 352(9124):275-278, 1998. PMID: 9690407. FMRIDCID: . WOBIB: 137.
INTERPRETATION: Our findings establish central nervous system dysfunction in the region of the hypothalamus as the primum movens in the pathophysiology of cluster headacheArne May; Anish Bahra; Christian Büchel; Richard S. J. Frackowiak; Peter J. Goadsby. Hypothalamic activation in cluster headache attacks. Lancet 352(9124):275-278, 1998. PMID: 9690407. FMRIDCID: . WOBIB: 137.

Text count

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