| A number of extrastriate visual areas in the parieto-occipital cortex are
known from single-cell recordings of the macaque monkey to be involved in
the coding of eye-position signals in the brain | Ian Law; Claus Svarer; Egill Rostrup; Olaf B. Paulson. Parieto-occipital cortex activation during self-generated eye movements in
the dark.
Brain 121 ( Pt 11):2189-200, 1998.
PMID: 9827777.
WOBIB: 1.
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| Only for the group of
male subjects was there evidence of a significant activation of the
thalamus and hypothalamus, a sexually dimorphic area of the brain known to
play a pivotal role in physiological arousal and sexual behavior | Sherif Karama; Andre R. Lecours; Jean-Maxime Leroux; Pierre Bourgouin; Gilles Beaudoin; Sven Joubert; Mario Beauregard. Areas of brain activation in males and females during viewing of erotic
film excerpts.
Human Brain Mapping 16(1):1-13, 2002.
PMID: 11870922.
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|
| These findings reveal the existence of
similarities and dissimilarities in the way the brain of both genders
responds to erotic stimuli | Sherif Karama; Andre R. Lecours; Jean-Maxime Leroux; Pierre Bourgouin; Gilles Beaudoin; Sven Joubert; Mario Beauregard. Areas of brain activation in males and females during viewing of erotic
film excerpts.
Human Brain Mapping 16(1):1-13, 2002.
PMID: 11870922.
WOBIB: 4.
|
| We hypothesize that brain regions
representing object categories that rely on detailed central scrutiny
(such as faces) are more strongly associated with processing of central
information, compared to representations of objects that may be recognized
by more peripheral information (such as buildings or scenes) | I Levy; U Hasson; G Avidan; T Hendler; R Malach. Center-periphery organization of human object areas.
Nature Neuroscience 4(5):533-9, 2001.
PMID: 11319563.
DOI: 10.1038/87490.
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| Functional MRI (fMRI) was used to examine human brain activity within the
dorsolateral prefrontal cortex during a sensorimotor task that had been
proposed to require selection between several responses, a cognitive
concept termed "willed action" in a positron emission tomography (PET)
study by Frith et al | F. Hyder; E. A. Phelps; C. J. Wiggins; K. S. Labar; A. M. Blamire; R. G. Shulman. "Willed action": a functional MRI study of the human prefrontal cortex during a sensorimotor task.
Proc Natl Acad Sci U S A 94(13):6989-6994, 1997.
PMID: 9192679.
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| Multiple brain areas,
including bilateral secondary somatosensory cortices (SII) and insula, and
the frontal lobe and thalamus contralateral to the stimulus side, were
found to be involved in the response to painful stimulation | X. Xu; H. Fukuyama; S. Yazawa; T. Mima; T. Hanakawa; Y. Magata; M. Kanda; N. Fujiwara; K. Shindo; T. Nagamine; H. Shibasaki. Functional localization of pain perception in the human brain studied by PET.
NeuroReport 8(2):555-559, 1997.
PMID: 9080447.
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| Brain activation was measured with
15O-PET, and significant changes in regional normalized counts (rNC) were
evaluated using statistical parametric mapping (SPM96) software | K. Hugdahl; Ian Law; S. Kyllingsbaek; K. Bronnick; Anders Gade; Olaf B. Paulson. Effects of attention on dichotic listening: an 15O-PET study.
Human Brain Mapping 10(2):87-97, 2000.
PMID: 10864233.
WOBIB: 14.
|
|
Functional magnetic resonance imaging (fMRI) was used to examine changes
in activation of posterior brain regions associated with the acquisition
of mirror-reading skill for novel and practiced stimuli | Russell A. Poldrack; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. The neural basis of visual skill learning: an fMRI study of mirror
reading.
Cerebral Cortex 8(1):1-10, 1998.
PMID: 9510380.
WOBIB: 15.
|
| To localize a central nervous feed-forward mechanism involved in
cardiovascular regulation during exercise, brain activation patterns were
measured in eight subjects by employing positron emission tomography and
oxygen-15-labeled water | M. Nowak; K. S. Olsen; I. Law; Søren Holm; O. B. Paulson; N. H. Secher. Command-related distribution of regional cerebral blood flow during attempted handgrip.
Journal of Applied Physiology 86(3):819-824, 1999.
PMID: 10066691.
WOBIB: 16.
|
| Micturition versus rest was associated with
bilateral activation of areas close to the postcentral gyrus, inferior
frontal gyrus, globus pallidus, cortex cerebelli, vermis and midbrain | S. Nour; Claus Svarer; J. K. Kristensen; O. B. Paulson; I. Law. Cerebral activation during micturition in normal men.
Brain 123 ( Pt 4):781-9, 2000.
PMID: 10734009.
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| For example we did not find any activation in brain areas known
to be involved in lexical or verbal processing nor activations in cortical
regions known to be involved in object identification or classification | K. Jordan; H. J. Heinze; K. Lutz; M. Kanowski; L. Jancke. Cortical activations during the mental rotation of different visual objects.
NeuroImage 13(1):143-52, 2001.
PMID: 11133317.
DOI: 10.1006/nimg.2000.0677.
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| Medial temporal brain regions such as the hippocampal formation and
parahippocampal cortex have been generally implicated in navigation and
visual memory | R. Epstein; N. Kanwisher. A cortical representation of the local visual environment.
Nature 392(6676):598-601, 1998.
PMID: 9560155.
DOI: 10.1038/33402.
WOBIB: 27.
|
| To identify the brain structures implicated in mental
transformation of size, we measured the distribution of regional cerebral
blood flow (rCBF) by positron emission tomography (PET) in 12 normal
subjects who compared random stimulus patterns with respect to shape
regardless of variations in size in a one-back match-to-sample paradigm | A. Larsen; C. Bundesen; S. Kyllingsbaek; O. B. Paulson; I. Law. Brain activation during mental transformation of size.
Journal of Cognitive Neuroscience 12(5):763-74, 2000.
PMID: 11054919.
WOBIB: 30.
|
| The
detected brain structures implicated in mental transformation of size were
primarily located in the dorsal pathways, comprising structures in the
occipital, parietal, and temporal transition zone (predominantly in the
left hemisphere), posterior parietal cortex (bilaterally), area MT/V5
(left), and vermis (bilaterally) | A. Larsen; C. Bundesen; S. Kyllingsbaek; O. B. Paulson; I. Law. Brain activation during mental transformation of size.
Journal of Cognitive Neuroscience 12(5):763-74, 2000.
PMID: 11054919.
WOBIB: 30.
|
| Human lesion data indicate that the basal forebrain or orbitofrontal
cortex, or both, as well as medial temporal and diencephalic structures,
is important for normal memory and that its disruption causes the pure
amnesic syndrome, in which episodic memory is grossly impaired while other
kinds of memory remain preserved | Toshikatsu Fujii; Jiro Okuda; Takashi Tsukiura; Hiroya Ohtake; Rina Miura; Reiko Fukatsu; Kyoko Suzuki; Ryuta Kawashima; Masatoshi Itoh; Hiroshi Fukuda; Atsushi Yamadori. The role of the basal forebrain in episodic memory retrieval: a positron emission tomography study.
NeuroImage 15(3):501-8, 2002.
PMID: 11848693.
DOI: 10.1006/nimg.2001.0995.
WOBIB: 32.
|
| Among these critical areas, functional
imaging studies have so far failed to detect activation of the basal
forebrain, although activation in the nearby orbitofrontal cortex has been
reported during episodic memory retrieval | Toshikatsu Fujii; Jiro Okuda; Takashi Tsukiura; Hiroya Ohtake; Rina Miura; Reiko Fukatsu; Kyoko Suzuki; Ryuta Kawashima; Masatoshi Itoh; Hiroshi Fukuda; Atsushi Yamadori. The role of the basal forebrain in episodic memory retrieval: a positron emission tomography study.
NeuroImage 15(3):501-8, 2002.
PMID: 11848693.
DOI: 10.1006/nimg.2001.0995.
WOBIB: 32.
|
| We employed positron emission
tomography to elucidate the neural basis of episodic memory recall
utilizing two types of time cues and successfully detected activity in the
basal forebrain for the first time | Toshikatsu Fujii; Jiro Okuda; Takashi Tsukiura; Hiroya Ohtake; Rina Miura; Reiko Fukatsu; Kyoko Suzuki; Ryuta Kawashima; Masatoshi Itoh; Hiroshi Fukuda; Atsushi Yamadori. The role of the basal forebrain in episodic memory retrieval: a positron emission tomography study.
NeuroImage 15(3):501-8, 2002.
PMID: 11848693.
DOI: 10.1006/nimg.2001.0995.
WOBIB: 32.
|
| Specifically, recall of previously
memorized words from temporal cues was associated with activity in the
basal forebrain, right middle frontal gyrus, right superior temporal
gyrus, and posterior cingulate gyrus, whereas their recall from person
cues was associated with activity in the left insula, right middle frontal
gyrus, and posterior cingulate gyrus | Toshikatsu Fujii; Jiro Okuda; Takashi Tsukiura; Hiroya Ohtake; Rina Miura; Reiko Fukatsu; Kyoko Suzuki; Ryuta Kawashima; Masatoshi Itoh; Hiroshi Fukuda; Atsushi Yamadori. The role of the basal forebrain in episodic memory retrieval: a positron emission tomography study.
NeuroImage 15(3):501-8, 2002.
PMID: 11848693.
DOI: 10.1006/nimg.2001.0995.
WOBIB: 32.
|
| Furthermore, percentage increases of
regional blood flow in the basal forebrain were correlated with behavioral
data of successful recall | Toshikatsu Fujii; Jiro Okuda; Takashi Tsukiura; Hiroya Ohtake; Rina Miura; Reiko Fukatsu; Kyoko Suzuki; Ryuta Kawashima; Masatoshi Itoh; Hiroshi Fukuda; Atsushi Yamadori. The role of the basal forebrain in episodic memory retrieval: a positron emission tomography study.
NeuroImage 15(3):501-8, 2002.
PMID: 11848693.
DOI: 10.1006/nimg.2001.0995.
WOBIB: 32.
|
| Our results provide clear evidence that the
human basal forebrain has a specific role in episodic memory recall,
especially that from time-contextual information | Toshikatsu Fujii; Jiro Okuda; Takashi Tsukiura; Hiroya Ohtake; Rina Miura; Reiko Fukatsu; Kyoko Suzuki; Ryuta Kawashima; Masatoshi Itoh; Hiroshi Fukuda; Atsushi Yamadori. The role of the basal forebrain in episodic memory retrieval: a positron emission tomography study.
NeuroImage 15(3):501-8, 2002.
PMID: 11848693.
DOI: 10.1006/nimg.2001.0995.
WOBIB: 32.
|
| We isolated brain areas activated during the viewing of
point-light figures, then compared those areas to regions known to be
involved in coherent-motion perception and kinetic-boundary perception | E. Grossman; M. Donnelly; R. Price; D. Pickens; V. Morgan; G. Neighbor; R. Blake. Brain areas involved in perception of biological motion.
Journal of Cognitive Neuroscience 12(5):711-20, 2000.
PMID: 11054914.
WOBIB: 33.
|
| The neural basis of navigation by humans was investigated with functional
neuroimaging of brain activity during navigation in a familiar, yet
complex virtual reality town | E. A. Maguire; N. Burgess; J. G. Donnett; Richard S. J. Frackowiak; C. D. Frith; J. O'Keefe. Knowing where and getting there: a human navigation network.
Science 280(5365):921-4, 1998.
PMID: 9572740.
WOBIB: 38.
|
| These
two right-side brain structures function in the context of associated
activity in right inferior parietal and bilateral medial parietal regions
that support egocentric movement through the virtual town, and activity in
other left-side regions (hippocampus, frontal cortex) probably involved in
nonspatial aspects of navigation | E. A. Maguire; N. Burgess; J. G. Donnett; Richard S. J. Frackowiak; C. D. Frith; J. O'Keefe. Knowing where and getting there: a human navigation network.
Science 280(5365):921-4, 1998.
PMID: 9572740.
WOBIB: 38.
|
| These findings outline a network of
brain areas that support navigation in humans and link the functions of
these regions to physiological observations in other mammals | E. A. Maguire; N. Burgess; J. G. Donnett; Richard S. J. Frackowiak; C. D. Frith; J. O'Keefe. Knowing where and getting there: a human navigation network.
Science 280(5365):921-4, 1998.
PMID: 9572740.
WOBIB: 38.
|
|
We measured brain activity using functional magnetic resonance imaging
(fMRI) during performance of the flanker task | E. Hazeltine; Russell Poldrack; John D. E. Gabrieli. Neural activation during response competition.
Journal of Cognitive Neuroscience 12(Supplement 2):118-29, 2000.
PMID: 11506652.
DOI: 10.1162/089892900563984.
FMRIDCID: 2-2000-11173.
WOBIB: 40.
|
|
In this study we used functional magnetic resonance imaging (fMRI) of the
entire brain to determine the patterns of activation that occurred while
subjects performed a visually guided motor task | J. M. Ellermann; J. D. Siegal; J. P. Strupp; T. J. Ebner; K. Ugurbil. Activation of visuomotor systems during visually guided movements: a
functional MRI study.
Journal of Magnetic Resonance 131(2):272-85, 1998.
PMID: 9571103.
WOBIB: 45.
|
|
Subsequently, each subject's brain was normalized to Talairach
coordinates, and the individual maps were compared on a pixel by pixel
basis | J. M. Ellermann; J. D. Siegal; J. P. Strupp; T. J. Ebner; K. Ugurbil. Activation of visuomotor systems during visually guided movements: a
functional MRI study.
Journal of Magnetic Resonance 131(2):272-85, 1998.
PMID: 9571103.
WOBIB: 45.
|
| Deduction activated
areas near right brain homologues of left language areas in middle
temporal lobe, inferior frontal cortex and basal ganglia, as well as right
amygdala, but not spatial-visual areas | L. M. Parsons; D. Osherson. New Evidence for Distinct Right and Left Brain Systems for Deductive versus Probabilistic Reasoning.
Cerebral Cortex 11(10):954-65, 2001.
PMID: 11549618.
WOBIB: 47.
|
| Using
positron emission tomography and H(2)(15)O, we aimed to identify brain
regions that change their neural activity in association with changes in
neural processing of visual and/or somatosensory information when humans
use a simple tool | K. Inoue; R. Kawashima; Motoaki Sugiura; A. Ogawa; T. Schormann; Karl Zilles; Hiroshi Fukuda. Activation in the ipsilateral posterior parietal cortex during tool use: a
PET study.
NeuroImage 14(6):1469-75, 2001.
PMID: 11707103.
DOI: 10.1006/nimg.2001.0942.
WOBIB: 48.
|
| PET was used to map brain regions that are associated
with the observation of meaningful and meaningless hand actions | Jean Decety; J. Grezes; N. Costes; Daniela Perani; Marc Jeannerod; E. Procyk; F. Grassi; F. Fazio. Brain activity during observation of actions. Influence of action content
and subject's strategy.
Brain 120 ( Pt 10):1763-77, 1997.
PMID: 9365369.
WOBIB: 49.
|
| We found that differences in the meaning of the action,
irrespective of the strategy used during observation, lead to different
patterns of brain activity and clear left/right asymmetries | Jean Decety; J. Grezes; N. Costes; Daniela Perani; Marc Jeannerod; E. Procyk; F. Grassi; F. Fazio. Brain activity during observation of actions. Influence of action content
and subject's strategy.
Brain 120 ( Pt 10):1763-77, 1997.
PMID: 9365369.
WOBIB: 49.
|
| Thus, the pattern of brain
activation during observation of actions is dependent both on the nature
of the required executive processing and the type of the extrinsic
properties of the action presented | Jean Decety; J. Grezes; N. Costes; Daniela Perani; Marc Jeannerod; E. Procyk; F. Grassi; F. Fazio. Brain activity during observation of actions. Influence of action content
and subject's strategy.
Brain 120 ( Pt 10):1763-77, 1997.
PMID: 9365369.
WOBIB: 49.
|
| Localized, task-induced decreases in cerebral blood flow are a frequent
finding in functional brain imaging research but remain poorly understood | J. R. Binder; J. A. Frost; T. A. Hammeke; P. S. Bellgowan; S. M. Rao; R. W. Cox. Conceptual processing during the conscious resting state. A functional MRI
study.
Journal of Cognitive Neuroscience 11(1):80-95, 1999.
PMID: 9950716.
WOBIB: 50.
|
| Furthermore, comparisons between
conceptual and nonconceptual tasks should show activation during
conceptual tasks of the same brain areas that are 'deactivated' relative
to rest | J. R. Binder; J. A. Frost; T. A. Hammeke; P. S. Bellgowan; S. M. Rao; R. W. Cox. Conceptual processing during the conscious resting state. A functional MRI
study.
Journal of Cognitive Neuroscience 11(1):80-95, 1999.
PMID: 9950716.
WOBIB: 50.
|
| This result is consistent with the proposal that perceptual
tasks interrupt processes ongoing during rest that involve many of the
same brain areas engaged during semantic retrieval | J. R. Binder; J. A. Frost; T. A. Hammeke; P. S. Bellgowan; S. M. Rao; R. W. Cox. Conceptual processing during the conscious resting state. A functional MRI
study.
Journal of Cognitive Neuroscience 11(1):80-95, 1999.
PMID: 9950716.
WOBIB: 50.
|
| As further evidence
for this model, the same network of brain areas was activated in two
direct comparisons between semantic and perceptual processing tasks | J. R. Binder; J. A. Frost; T. A. Hammeke; P. S. Bellgowan; S. M. Rao; R. W. Cox. Conceptual processing during the conscious resting state. A functional MRI
study.
Journal of Cognitive Neuroscience 11(1):80-95, 1999.
PMID: 9950716.
WOBIB: 50.
|
| In general, the current findings confirm the
distinction between maintenance and manipulative processes, highlight the
functional heterogeneity in the prefrontal cortex (PFC), and suggest a
more dynamic view of WM as a process requiring the coordinated interaction
of anatomically distinct brain areas | L. Cornette; P. Dupont; E. Salmon; G. A. Orban. The neural substrate of orientation working memory.
Journal of Cognitive Neuroscience 13(6):813-28, 2001.
PMID: 11564325.
DOI: 10.1162/08989290152541476.
WOBIB: 51.
|
| This work investigates whether the brain assigns special cortical areas
for the processing of kinetic contours | Semir Zeki; R. J. Perry; A. Bartels. The processing of kinetic contours in the brain.
Cerebral Cortex 13(2):189-202, 2003.
PMID: 12507950.
WOBIB: 52.
|
| In human imaging experiments, we
compared the brain activity produced in the so-called 'kinetic occipital'
area ('KO') when humans perceive shapes generated from kinetic boundaries
or from equiluminant colors | Semir Zeki; R. J. Perry; A. Bartels. The processing of kinetic contours in the brain.
Cerebral Cortex 13(2):189-202, 2003.
PMID: 12507950.
WOBIB: 52.
|
| We
conclude that there is no present evidence for a visual area specialized
for the processing of kinetic contours in the primate visual brain | Semir Zeki; R. J. Perry; A. Bartels. The processing of kinetic contours in the brain.
Cerebral Cortex 13(2):189-202, 2003.
PMID: 12507950.
WOBIB: 52.
|
|
The activity in the brains of 17 subjects who were deeply in love was
scanned using fMRI, while they viewed pictures of their partners, and
compared with the activity produced by viewing pictures of three friends
of similar age, sex and duration of friendship as their partners | Andreas Bartels; Semir Zeki. The neural basis of romantic love.
NeuroReport 11(17):3829-3834, 2000.
PMID: 11117499.
WOBIB: 54.
|
| Defining a baseline state in the human brain, arguably
our most complex system, poses a particular challenge | Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function.
Proc Natl Acad Sci U S A 98(2):676-82, 2001.
PMID: 11209064.
DOI: 10.1073/pnas.98.2.676.
WOBIB: 55.
|
| Despite this
prediction we identify a baseline state of the normal adult human brain in
terms of the brain oxygen extraction fraction or OEF | Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function.
Proc Natl Acad Sci U S A 98(2):676-82, 2001.
PMID: 11209064.
DOI: 10.1073/pnas.98.2.676.
WOBIB: 55.
|
| The OEF is defined
as the ratio of oxygen used by the brain to oxygen delivered by flowing
blood and is remarkably uniform in the awake but resting state (e | Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function.
Proc Natl Acad Sci U S A 98(2):676-82, 2001.
PMID: 11209064.
DOI: 10.1073/pnas.98.2.676.
WOBIB: 55.
|
| We used
quantitative metabolic and circulatory measurements from positron-emission
tomography to obtain the OEF regionally throughout the brain | Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function.
Proc Natl Acad Sci U S A 98(2):676-82, 2001.
PMID: 11209064.
DOI: 10.1073/pnas.98.2.676.
WOBIB: 55.
|
| These decreases suggest the existence of an organized,
baseline default mode of brain function that is suspended during specific
goal-directed behaviors | Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function.
Proc Natl Acad Sci U S A 98(2):676-82, 2001.
PMID: 11209064.
DOI: 10.1073/pnas.98.2.676.
WOBIB: 55.
|
| We used functional magnetic resonance imaging (fMRI) to determine whether
similar brain regions activate during noxious hot and cold stimulation | I. Tracey; L. Becerra; I. Chang; H. Breiter; L. Jenkins; D. Borsook; R. G. Gonzalez. Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study.
Neuroscience Letters 288(2):159-62, 2000.
PMID: 10876085.
WOBIB: 57.
|
|
Six male subjects underwent whole brain fMRI during phasic delivery of
noxious hot (46 degrees C) and noxious cold (5 degrees C) stimulation to
the dorsum of the left hand | I. Tracey; L. Becerra; I. Chang; H. Breiter; L. Jenkins; D. Borsook; R. G. Gonzalez. Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study.
Neuroscience Letters 288(2):159-62, 2000.
PMID: 10876085.
WOBIB: 57.
|
| It has previously been suggested that the activity in sensory regions of
the brain can be modulated by attentional mechanisms during parallel
cognitive processing | P. Petrovic; K. M. Petersson; P. H. Ghatan; S. Stone-Elander; M. Ingvar. Pain-related cerebral activation is altered by a distracting cognitive task.
Pain 85(1-2):19-30, 2000.
PMID: 10692599.
WOBIB: 58.
|
| The activity
in the somatosensory association areas and periaqueductal gray/midbrain
were significantly modified, i | P. Petrovic; K. M. Petersson; P. H. Ghatan; S. Stone-Elander; M. Ingvar. Pain-related cerebral activation is altered by a distracting cognitive task.
Pain 85(1-2):19-30, 2000.
PMID: 10692599.
WOBIB: 58.
|
| Our current understanding of spatial behaviour and parietal lobe function
is largely based on the belief that spatial neglect in humans (a lack of
awareness of space on the side of the body contralateral to a brain
injury) is typically associated with lesions of the posterior parietal
lobe | Hans-Otto Karnath; S. Ferber; M. Himmelbach. Spatial awareness is a function of the temporal not the posterior parietal
lobe.
Nature 411(6840):950-3, 2001.
PMID: 11418859.
DOI: 10.1038/35082075.
WOBIB: 59.
|
| Unlike the monkey brain, spatial awareness in humans is a
function largely confined to the right superior temporal cortex, a
location topographically reminiscent of that for language on the left | Hans-Otto Karnath; S. Ferber; M. Himmelbach. Spatial awareness is a function of the temporal not the posterior parietal
lobe.
Nature 411(6840):950-3, 2001.
PMID: 11418859.
DOI: 10.1038/35082075.
WOBIB: 59.
|
|
Hence, the decisive phylogenetic transition from monkey to human brain
seems to be a restriction of a formerly bilateral function to the right
side, rather than a shift from the temporal to the parietal lobe | Hans-Otto Karnath; S. Ferber; M. Himmelbach. Spatial awareness is a function of the temporal not the posterior parietal
lobe.
Nature 411(6840):950-3, 2001.
PMID: 11418859.
DOI: 10.1038/35082075.
WOBIB: 59.
|
| Brain activity was studied by fMRI in 18 healthy subjects during
stimulation of the thenar eminence of the hand with either warm
(non-painful, 40 degrees C) or hot (painful, 46-49 degrees C) stimuli
using a contact thermode | Jonathan C. W. Brooks; Turo J. Nurmikko; William E. Bimson; Krish D. Singh; Neil Roberts. fMRI of thermal pain: effects of stimulus laterality and attention.
NeuroImage 15(2):293-301, 2002.
PMID: 11798266.
DOI: 10.1006/nimg.2001.0974.
WOBIB: 60.
|
| Painful thermal stimulation of either hand elicited
significant activity over a large network of brain regions, including
insula, inferior frontal gyrus, cingulate gyrus, secondary somatosensory
cortex, cerebellum, and medial frontal gyrus (corrected P < 0 | Jonathan C. W. Brooks; Turo J. Nurmikko; William E. Bimson; Krish D. Singh; Neil Roberts. fMRI of thermal pain: effects of stimulus laterality and attention.
NeuroImage 15(2):293-301, 2002.
PMID: 11798266.
DOI: 10.1006/nimg.2001.0974.
WOBIB: 60.
|
| The CV
of the entire cortex was found to be significantly larger in AD,
suggesting increased heterogeneity at the whole brain level | Nora D. Volkow; Wei Zhu; Christoph A. Felder; Klaus Mueller; Tomihisa F. Welsh; Gene J. Wang; Mony J. de Leon. Changes in brain functional homogeneity in subjects with Alzheimer's
disease.
Psychiatry Research 114(1):39-50, 2002.
PMID: 11864808.
WOBIB: 61.
|
| The
enhanced heterogeneity for the global cortical pattern most likely
reflects variability in the degree of pathology among brain regions as
well as neuroanatomical disconnection | Nora D. Volkow; Wei Zhu; Christoph A. Felder; Klaus Mueller; Tomihisa F. Welsh; Gene J. Wang; Mony J. de Leon. Changes in brain functional homogeneity in subjects with Alzheimer's
disease.
Psychiatry Research 114(1):39-50, 2002.
PMID: 11864808.
WOBIB: 61.
|
| Structural MRIs of the brains of humans with extensive navigation
experience, licensed London taxi drivers, were analyzed and compared with
those of control subjects who did not drive taxis | E. A. Maguire; D. G. Gadian; I. S. Johnsrude; C. D. Good; J. Ashburner; Richard S. J. Frackowiak; C. D. Frith. Navigation-related structural change in the hippocampi of taxi drivers.
Proc Natl Acad Sci U S A 97(8):4398-403, 2000.
PMID: 10716738.
DOI: 10.1073/pnas.070039597.
WOBIB: 63.
|
| It seems that there is a capacity for local plastic change in the
structure of the healthy adult human brain in response to environmental
demands | E. A. Maguire; D. G. Gadian; I. S. Johnsrude; C. D. Good; J. Ashburner; Richard S. J. Frackowiak; C. D. Frith. Navigation-related structural change in the hippocampi of taxi drivers.
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| The purpose of this study was to identify brain regions underlying
internally generated anticipatory biases toward locations where
significant events are expected to occur | D. M. Small; D. R. Gitelman; M. D. Gregory; A. C. Nobre; T. B. Parrish; M-M Mesulam. The posterior cingulate and medial prefrontal cortex mediate the
anticipatory allocation of spatial attention.
NeuroImage 18(3):633-41, 2003.
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| In order to localize this unmasking
in the human brain, we have used positron emission tomography (PET) to
compare the cortical activation patterns evoked by the thermal grill and
by cool, warm, noxious cold and noxious heat stimuli | A. D. Craig; Eric M. Reiman; A. Evans; M. C. Bushnell. Functional imaging of an illusion of pain.
Nature 384(6606):258-60, 1996.
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|
In order to identify brain activity specifically associated with adoption
of an intentional stance, we used a paradigm that allowed tight control of
other cognitive demands | Helen L. Gallagher; Anthony I. Jack; Andreas Roepstorff; Christopher D. Frith. Imaging the intentional stance in a competitive game.
NeuroImage 16(3 Pt 1):814-21, 2002.
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| However, this is the
first study suggesting a specific link between activity in this brain
region and the adoption of an intentional stance | Helen L. Gallagher; Anthony I. Jack; Andreas Roepstorff; Christopher D. Frith. Imaging the intentional stance in a competitive game.
NeuroImage 16(3 Pt 1):814-21, 2002.
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| It has been argued that the role of the hippocampus in memory is
time-limited: during a period of memory consolidation, other brain regions
such as the neocortex are said to acquire the ability to support memory
retention and retrieval on their own | L. Ryan; L. Nadel; K. Keil; K. Putnam; D. Schnyer; T. Trouard; M. Moscovitch. Hippocampal complex and retrieval of recent and very remote
autobiographical memories: evidence from functional magnetic resonance
imaging in neurologically intact people.
Hippocampus 11(6):707-14, 2001.
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| Conjunction
analysis revealed a network of brain areas jointly activated during
conscious REST as compared to the nine cognitive tasks, including the
bilateral angular gyrus, the left anterior precuneus and posterior
cingulate cortex, the left medial frontal and anterior cingulate cortex,
the left superior and medial frontal sulcus, and the left inferior frontal
cortex | B. Mazoyer; L. Zago; E. Mellet; S. Bricogne; O. Etard; O. Houde; F. Crivello; M. Joliot; L. Petit; N. Tzourio-Mazoyer. Cortical networks for working memory and executive functions sustain the conscious resting state in man.
Brain Research Bulletin 54(3):287-298, 2001.
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| These results suggest that brain activity during conscious REST is
sustained by a large scale network of heteromodal associative parietal and
frontal cortical areas, that can be further hierarchically organized in an
episodic working memory parieto-frontal network, driven in part by
emotions, working under the supervision of an executive left prefrontal
network | B. Mazoyer; L. Zago; E. Mellet; S. Bricogne; O. Etard; O. Houde; F. Crivello; M. Joliot; L. Petit; N. Tzourio-Mazoyer. Cortical networks for working memory and executive functions sustain the conscious resting state in man.
Brain Research Bulletin 54(3):287-298, 2001.
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| Cortical activity due to a thermal painful stimulus applied to the right
hand was studied in the middle third of the contralateral brain and
compared to activations for vibrotactile and motor tasks using the same
body part, in nine normal subjects | P. A. Gelnar; B. R. Krauss; P. R. Sheehe; N. M. Szeverenyi; A. V. Apkarian. A comparative fMRI study of cortical representations for thermal painful,
vibrotactile, and motor performance tasks.
NeuroImage 10(4):460-82, 1999.
PMID: 10493903.
DOI: 10.1006/nimg.1999.0482.
WOBIB: 75.
|
| The study indicates that fMRI enables
examination of cortical networks subserving pain perception at an
anatomical detail not available with other brain imaging techniques and
shows that this cortical network underlying pain perception shares
components with the networks underlying touch perception and motor
execution | P. A. Gelnar; B. R. Krauss; P. R. Sheehe; N. M. Szeverenyi; A. V. Apkarian. A comparative fMRI study of cortical representations for thermal painful,
vibrotactile, and motor performance tasks.
NeuroImage 10(4):460-82, 1999.
PMID: 10493903.
DOI: 10.1006/nimg.1999.0482.
WOBIB: 75.
|
| In this study, we used positron
emission tomography in 11 healthy volunteers to identify the brain areas
in which hypnosis modulates cerebral responses to a noxious stimulus | M. E. Faymonville; S. Laureys; C. Degueldre; G. DelFiore; A. Luxen; G. Franck; M. Lamy; P. Maquet. Neural mechanisms of antinociceptive effects of hypnosis.
Anesthesiology 92(5):1257-67, 2000.
PMID: 10781270.
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| , brain areas that would be
more or less activated in hypnosis than in control conditions, under
noxious stimulation) | M. E. Faymonville; S. Laureys; C. Degueldre; G. DelFiore; A. Luxen; G. Franck; M. Lamy; P. Maquet. Neural mechanisms of antinociceptive effects of hypnosis.
Anesthesiology 92(5):1257-67, 2000.
PMID: 10781270.
WOBIB: 76.
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| Cortically, brain blood flow decreased in the
social phobics and increased in the comparison subjects more during public
than private speaking in the orbitofrontal and insular cortices as well as
in the temporal pole and increased less in the social phobics than in the
comparison group in the parietal and secondary visual cortices | M. Tillfors; T. Furmark; I. Marteinsdottir; Håkan Fischer; A. Pissiota; B. Langstrom; M. Fredrikson. Cerebral blood flow in subjects with social phobia during stressful speaking tasks: a PET study.
American Journal of Psychiatry 158(8):1220-6, 2001.
PMID: 11481154.
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| Functional neuroimaging is uniquely placed to examine the dynamic nature
of normal human memory, the distributed brain networks that support it,
and how they are modulated | E. A. Maguire; C. J. Mummery. Differential modulation of a common memory retrieval network revealed by
positron emission tomography.
Hippocampus 9(1):54-61, 1999.
PMID: 10088900.
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|
| Recollection of each of the
resultant four memory subtypes-autobiographical events, public events,
autobiographical facts, and general knowledge-was associated with
activation of a common network of brain regions | E. A. Maguire; C. J. Mummery. Differential modulation of a common memory retrieval network revealed by
positron emission tomography.
Hippocampus 9(1):54-61, 1999.
PMID: 10088900.
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|
| Brain imaging with positron emission tomography has identified some of the
principal cerebral structures of a central network activated by pain | T. R. Tolle; T. Kaufmann; T. Siessmeier; S. Lautenbacher; A. Berthele; F. Munz; W. Zieglgansberger; F. Willoch; M. Schwaiger; B. Conrad; P. Bartenstein. Region-specific encoding of sensory and affective components of pain in
the human brain: a positron emission tomography correlation analysis.
Annals of Neurology 45(1):40-47, 1999.
PMID: 9894875.
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| The results of
our activation study indicate that different functions in pain processing
can be attributed to different brain regions; ie, the gating function
reflected by the pain threshold appeared to be related to anterior
cingulate cortex, the frontal inferior cortex, and the thalamus, the
coding of pain intensity to the periventricular gray as well as to the
posterior cingulate cortex, and the encoding of pain unpleasantness to the
posterior sector of the anterior cingulate cortex | T. R. Tolle; T. Kaufmann; T. Siessmeier; S. Lautenbacher; A. Berthele; F. Munz; W. Zieglgansberger; F. Willoch; M. Schwaiger; B. Conrad; P. Bartenstein. Region-specific encoding of sensory and affective components of pain in
the human brain: a positron emission tomography correlation analysis.
Annals of Neurology 45(1):40-47, 1999.
PMID: 9894875.
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| We used event-related functional magnetic resonance imaging (efMRI) to
investigate brain regions showing differential responses as a function of
confidence in an episodic word recognition task | R. N. Henson; Michael D. Rugg; T. Shallice; R. J. Dolan. Confidence in recognition memory for words: dissociating right prefrontal
roles in episodic retrieval.
Journal of Cognitive Neuroscience 12(6):913-23, 2000.
PMID: 11177413.
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| Using H2 15O PET, we studied brain
responses to such predictable sensory events (tones) and to similar
unpredictable events and especially how the processing of predictable
sensory events is modified by the context of a causative self-generated
action | S. J. Blakemore; G. Rees; C. D. Frith. How do we predict the consequences of our actions? A functional imaging
study.
Neuropsychologia 36(6):521-9, 1998.
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| A commonality of other regions observed in this pair of
studies, as well as other studies of memory in the literature, suggests
that the human brain may contain a distributed multinodal general memory
system | Nancy C. Andreasen; D. S. O'Leary; T. Cizadlo; Stephan Arndt; K. Rezai; G. L. Watkins; L. L. Ponto; R. D. Hichwa. II. PET studies of memory: novel versus practiced free recall of word
lists.
NeuroImage 2(4):296-305, 1995.
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| OBJECTIVES: To assess the suitability of analyzing functional images of
brain serotonin (5-HT) synthesis with statistical parametric mapping
(SPM), and to investigate further possible sex-related regional
differences | H. Okazawa; M. Leyton; C. Benkelfat; S. Mzengeza; M. Diksic. Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan.
Journal of Psychiatry Neuroscience 25(4):359-370, 2000.
PMID: 11022401.
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|
| INTERVENTION: Participants' brains were scanned with
positron-emission tomography (PET) after intravenous injection of
alpha-[11C]methyl-L-tryptophan (alpha-[11C]MTrp) | H. Okazawa; M. Leyton; C. Benkelfat; S. Mzengeza; M. Diksic. Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan.
Journal of Psychiatry Neuroscience 25(4):359-370, 2000.
PMID: 11022401.
WOBIB: 89.
|
| CONCLUSION: SPM analyses
of PET alpha-[11C]MTrp data may be of value for identifying regional
differences in brain 5-HT synthesis between groups, and in investigating
the effects of psychotropic drugs | H. Okazawa; M. Leyton; C. Benkelfat; S. Mzengeza; M. Diksic. Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan.
Journal of Psychiatry Neuroscience 25(4):359-370, 2000.
PMID: 11022401.
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| Neuroimaging studies of natural memories may reveal
distinctive patterns of brain activation and may have particular value in
assessing clinical disorders of memory | R. J. Maddock; A. S. Garrett; Michael H. Buonocore. Remembering familiar people: the posterior cingulate cortex and
autobiographical memory retrieval.
Neuroscience 104(3):667-76, 2001.
PMID: 11440800.
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| This study used functional
magnetic resonance imaging to investigate brain activation during
successful retrieval of autobiographical memories elicited by name-cued
recall of family members and friends | R. J. Maddock; A. S. Garrett; Michael H. Buonocore. Remembering familiar people: the posterior cingulate cortex and
autobiographical memory retrieval.
Neuroscience 104(3):667-76, 2001.
PMID: 11440800.
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| In
addition, the available studies have not used recently developed brain
mapping algorithms to characterize the progression of Alzheimer's disease
throughout the brain, and none considered the statistical power of
regional cerebral glucose metabolism in testing the ability of treatments
to attenuate the progression of dementia | Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A
Potential Outcome Measure in Alzheimer's Disease Treatment Studies.
American Journal of Psychiatry 159(5):738-45, 2002.
PMID: 11986126.
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|
| METHOD: The authors used FDG PET
and a brain mapping algorithm to investigate cross-sectional reductions in
regional cerebral glucose metabolism, longitudinal decline in regional
cerebral glucose metabolism after a 1-year follow-up, and the power of
this method to evaluate treatments for Alzheimer's disease in patients
with mild to moderate dementia | Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A
Potential Outcome Measure in Alzheimer's Disease Treatment Studies.
American Journal of Psychiatry 159(5):738-45, 2002.
PMID: 11986126.
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| CONCLUSIONS: These findings indicate that brain
metabolism as assessed by FDG PET during mental rest is a sensitive marker
of disease progression in Alzheimer's disease over a 1-year period | Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A
Potential Outcome Measure in Alzheimer's Disease Treatment Studies.
American Journal of Psychiatry 159(5):738-45, 2002.
PMID: 11986126.
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|
| The results show that the positron emission tomography and
(18)F-fluoro-deoxyglucose ((18)FDG-PET) brain mapping results could be
partially reproduced, and suggest that PET brain mapping of cancer
patients has a potential clinical application to the field of
psycho-oncology and cancer patient care | M. Tashiro; F. D. Juengling; M. J. Reinhardt; I. Brink; S. Hoegerle; M. Mix; K. Kubota; K. Yamaguchi; M. Itoh; H. Sasaki; E. Moser; E. U. Nitzsche. Reproducibility of PET brain mapping of cancer patients.
Psychooncology 9(2):157-63, 2000.
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| Pleasant and unpleasant
emotions were each distinguished from neutral emotion conditions by
significantly increased cerebral blood flow in the vicinity of the medial
prefrontal cortex (Brodmann's area 9), thalamus, hypothalamus and midbrain
(P < 0 | Richard D. Lane; Eric M. Reiman; M. M. Bradley; P. J. Lang; Geoffrey L. Ahern; Richard J. Davidson; Gary E. Schwartz. Neuroanatomical correlates of pleasant and unpleasant emotion.
Neuropsychologia 35(11):1437-44, 1997.
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| To learn about the sequence of brain activation patterns during heat pain,
we acquired positron emission tomographic (PET) brain scans at different
times during repetitive heat stimulation (40 or 50 degrees C; 5-s contact)
of each subject's left forearm | K. L. Casey; T. J. Morrow; J. Lorenz; S. Minoshima. Temporal and spatial dynamics of human forebrain activity during heat
pain: analysis by positron emission tomography.
Journal of Neurophysiology 85(2):951-9, 2001.
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| These psychophysical
changes could be mediated by brain structures with increasing activity
from early to late PET scans or that are active only during late scans | K. L. Casey; T. J. Morrow; J. Lorenz; S. Minoshima. Temporal and spatial dynamics of human forebrain activity during heat
pain: analysis by positron emission tomography.
Journal of Neurophysiology 85(2):951-9, 2001.
PMID: 11160525.
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| Overall, the results
reveal that 1) the pattern of brain activation and the perception of heat
pain both change during repetitive noxious heat stimulation, 2) cortical
activity can be detected before subcortical responses appear, and 3)
timing the stimulation with respect to the scan period can, together with
psychophysical measurements, identify brain structures that are likely to
participate in the perception of pain | K. L. Casey; T. J. Morrow; J. Lorenz; S. Minoshima. Temporal and spatial dynamics of human forebrain activity during heat
pain: analysis by positron emission tomography.
Journal of Neurophysiology 85(2):951-9, 2001.
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| Here we use positron emission tomography
and statistical parametric mapping to study the brain state associated
with REM sleep in humans | P. Maquet; J. Peters; J. Aerts; G. Delfiore; C. Degueldre; A. Luxen; G. Franck. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming.
Nature 383(6596):163-6, 1996.
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| We report a group study of seven subjects who
maintained steady REM sleep during brain scanning and recalled dreams upon
awakening | P. Maquet; J. Peters; J. Aerts; G. Delfiore; C. Degueldre; A. Luxen; G. Franck. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming.
Nature 383(6596):163-6, 1996.
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| We
detected signal increase in the right middle temporal gyrus and left
prefrontal cortex during presentation of familiar faces, and in several
brain regions, including bilateral posterior cingulate gyri, bilateral
insulae and right middle occipital cortex during presentation of
unfamiliar faces | Mary L. Phillips; E. T. Bullmore; R. Howard; P. W. Woodruff; I. C. Wright; Steven C. R. Williams; A. Simmons; C. Andrew; M. Brammer; Anthony S. David. Investigation of facial recognition memory and happy and sad facial
expression perception: an fMRI study.
Psychiatry Research 83(3):127-38, 1998.
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| During presentation of happy facial expressions, we detected a
signal increase predominantly in the left anterior cingulate gyrus,
bilateral posterior cingulate gyri, medial frontal cortex and right
supramarginal gyrus, brain regions previously implicated in visuospatial
and emotion processing tasks | Mary L. Phillips; E. T. Bullmore; R. Howard; P. W. Woodruff; I. C. Wright; Steven C. R. Williams; A. Simmons; C. Andrew; M. Brammer; Anthony S. David. Investigation of facial recognition memory and happy and sad facial
expression perception: an fMRI study.
Psychiatry Research 83(3):127-38, 1998.
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| Subcortically,
conditioning increased rCBF bilaterally in the ventromedial thalamus, the
posterior hypothalamus and the central grey of the midbrain | M. Fredrikson; G. Wik; Håkan Fischer; J. Andersson. Affective and attentive neural networks in humans: a PET study of
Pavlovian conditioning.
NeuroReport 7(1):97-101, 1995.
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| Thus, the functional organization of
classical conditioning in humans involves autonomic, affective and
attentive brain mechanisms | M. Fredrikson; G. Wik; Håkan Fischer; J. Andersson. Affective and attentive neural networks in humans: a PET study of
Pavlovian conditioning.
NeuroReport 7(1):97-101, 1995.
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| Recent positron emission tomography (PET) studies have demonstrated areas
of pain processing in the human brain | L. J. Adler; F. E. Gyulai; D. J. Diehl; M. A. Mintun; P. M. Winter; L. L. Firestone. Regional brain activity changes associated with fentanyl analgesia elucidated by positron emission tomography.
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| Given the inhibitory effects of
opioids on neuronal activity, we predicted that fentanyl's analgesic
effects would be associated with suppression of pain-evoked responses in
these distinct brain areas | L. J. Adler; F. E. Gyulai; D. J. Diehl; M. A. Mintun; P. M. Winter; L. L. Firestone. Regional brain activity changes associated with fentanyl analgesia elucidated by positron emission tomography.
Anesthesia & Analgesia 84(1):120-126, 1997.
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| In
contrast to our hypothesis, these data indicate that fentanyl analgesia
involves augmentation of pain-evoked cerebral responses in certain areas,
as well as both activation and inhibition in other brain regions
unresponsive to pain stimulation alone | L. J. Adler; F. E. Gyulai; D. J. Diehl; M. A. Mintun; P. M. Winter; L. L. Firestone. Regional brain activity changes associated with fentanyl analgesia elucidated by positron emission tomography.
Anesthesia & Analgesia 84(1):120-126, 1997.
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| We wished to determine whether there are differences in the spatial
pattern and intensity of synaptic activity within the conscious human
forebrain when different forms and intensities of innocuous and noxious
thermal stimuli are experienced | K. L. Casey; S. Minoshima; T. J. Morrow; R. A. Koeppe. Comparison of human cerebral activation pattern during cutaneous warmth,
heat pain, and deep cold pain.
Journal of Neurophysiology 76(1):571-81, 1996.
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| The ipsilateral premotor cortex
and thalamus, and the medial dorsal midbrain and cerebellar vermis, also
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heat pain, and deep cold pain.
Journal of Neurophysiology 76(1):571-81, 1996.
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| Thus, the stress induced
by visual re-experience of a robbery is associated with altered activity
in paralimbic and cortical brain regions of relevance for cognition and
affect | Håkan Fischer; G. Wik; M. Fredrikson. Functional neuroanatomy of robbery re-experience: affective memories
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| A graded relationship between symptom intensity and
regional brain activity can thus be identified in obsessive-compulsive
disorder | Philip K. McGuire; C. J. Bench; C. D. Frith; I. M. Marks; Richard S. J. Frackowiak; R. J. Dolan. Functional anatomy of obsessive-compulsive phenomena.
British Journal of Psychiatry 164(4):459-468, 1994.
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| Positron emission tomography (PET) was used to identify brain regions
associated with two component processes of episodic retrieval; those
related to thinking back in subjective time (retrieval mode) and those
related to actual recovery of stored information (ecphory) | L. Nyberg; Endel Tulving; R. Habib; L. G. Nilsson; S. Kapur; S. Houle; Roberto Cabeza; A. R. McIntosh. Functional brain maps of retrieval mode and recovery of episodic
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| In contrast to the common view
that g reflects a broad sample of major cognitive functions, high-g tasks
do not show diffuse recruitment of multiple brain regions | John Duncan; Rüdiger J. Seitz; J. Kolodny; D. Bor; H. Herzog; A. Ahmed; F. N. Newell; H. Emslie. A neural basis for general intelligence.
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| Positron-emission tomography (PET) has identified specific
regions of the brain in which the rate of glucose metabolism declines
progressively in patients with probable Alzheimer's disease | Eric M. Reiman; R. J. Caselli; L. S. Yun; K. Chen; D. Bandy; S. Minoshima; S. N. Thibodeau; D. Osborne. Preclinical evidence of Alzheimer's disease in persons homozygous for the
epsilon 4 allele for apolipoprotein E.
New England Journal of Medicine 334(12):752-8, 1996.
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| We used PET
to investigate whether these same regions of the brain are affected in
subjects homozygous for the epsilon 4 allele before the onset of cognitive
impairment | Eric M. Reiman; R. J. Caselli; L. S. Yun; K. Chen; D. Bandy; S. Minoshima; S. N. Thibodeau; D. Osborne. Preclinical evidence of Alzheimer's disease in persons homozygous for the
epsilon 4 allele for apolipoprotein E.
New England Journal of Medicine 334(12):752-8, 1996.
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| In late middle
age, cognitively normal subjects who are homozygous for the epsilon 4
allele for apolipoprotein E have reduced glucose metabolism in the same
regions of the brain as in patients with probable Alzheimer's disease | Eric M. Reiman; R. J. Caselli; L. S. Yun; K. Chen; D. Bandy; S. Minoshima; S. N. Thibodeau; D. Osborne. Preclinical evidence of Alzheimer's disease in persons homozygous for the
epsilon 4 allele for apolipoprotein E.
New England Journal of Medicine 334(12):752-8, 1996.
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| Many "higher-order" mental functions are subserved by large-scale
neurocognitive networks comprising several spatially distributed and
functionally specialized brain regions | E. T. Bullmore; S. Rabe-Hesketh; R. G. Morris; Steven C. R. Williams; L. Gregory; J. A. Gray; M. J. Brammer. Functional magnetic resonance image analysis of a large-scale
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NeuroImage 4(1):16-33, 1996.
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| This revealed a large functional distance (negative connectivity)
between visual processing systems and all other brain regions in the space
of the first PC | E. T. Bullmore; S. Rabe-Hesketh; R. G. Morris; Steven C. R. Williams; L. Gregory; J. A. Gray; M. J. Brammer. Functional magnetic resonance image analysis of a large-scale
neurocognitive network.
NeuroImage 4(1):16-33, 1996.
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| Visual
input analysis systems (extrastriate cortex and angular gyrus) were
colocalized in the space of the first canonical variate (CV) and
significantly separated from all other brain regions | E. T. Bullmore; S. Rabe-Hesketh; R. G. Morris; Steven C. R. Williams; L. Gregory; J. A. Gray; M. J. Brammer. Functional magnetic resonance image analysis of a large-scale
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NeuroImage 4(1):16-33, 1996.
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| Furthermore, the unilateral cingulate activation indicates
that this forebrain area, thought to regulate emotions, contains an
unexpectedly specific representation of pain | J. D. Talbot; S. Marrett; Alan C. Evans; Ernst Meyer; M. C. Bushnell; G. H. Duncan. Multiple representations of pain in human cerebral cortex.
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|
These results demonstrate genetically driven variation in the response of
brain regions underlying human emotional behavior and suggest that
differential excitability of the amygdala to emotional stimuli may
contribute to the increased fear and anxiety typically associated with the
short SLC6A4 allele | Ahmad R. Hariri; Venkata S. Mattay; Alessandro Tessitore; Bhaskar Kolachana; Francesco Fera; David Goldman; Michael F. Egan; Daniel R. Weinberger. Serotonin transporter genetic variation and the response of the human amygdala.
Science 297(5580):400-3, 2002.
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| Pain is a diverse sensory and emotional experience that likely involves
activation of numerous regions of the brain | R. C. Coghill; J. D. Talbot; A. C. Evans; Ernst Meyer; Albert Gjedde; M. C. Bushnell; G. H. Duncan. Distributed processing of pain and vibration by the human brain.
Journal of Neuroscience 14(7):4095-108, 1994.
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|
In order to better characterize the processing of pain within the human
brain, activation produced by noxious stimuli was compared with that
produced by robust innocuous stimuli | R. C. Coghill; J. D. Talbot; A. C. Evans; Ernst Meyer; Albert Gjedde; M. C. Bushnell; G. H. Duncan. Distributed processing of pain and vibration by the human brain.
Journal of Neuroscience 14(7):4095-108, 1994.
PMID: 8027764.
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| The purpose of the present study was to determine whether gender
differences exist in the forebrain cerebral activation patterns of the
brain during pain perception | P. E. Paulson; S. Minoshima; T. J. Morrow; K. L. Casey. Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans.
Pain 76(1-2):223-9, 1998.
PMID: 9696477.
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| These pain-related
differences in brain activation may be attributed to gender, perceived
pain intensity, or to both factors | P. E. Paulson; S. Minoshima; T. J. Morrow; K. L. Casey. Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans.
Pain 76(1-2):223-9, 1998.
PMID: 9696477.
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| We used functional magnetic resonance imaging to examine
brain activation during the performance of evaluative judgments as opposed
to episodic and semantic memory retrieval | Stefan Zysset; Oswald Huber; Evelyn Ferstl; D. Y. von Cramon. The anterior frontomedian cortex and evaluative judgment: an fMRI study.
NeuroImage 15(4):983-91, 2002.
PMID: 11906238.
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| Findings from functional imaging studies have shown activation of the
brainstem during migraine without aura (MWOA) and activation of the
hypothalamus during cluster headache | A. Bahra; M. S. Matharu; Christian Büchel; Richard S. J. Frackowiak; P. J. Goadsby. Brainstem activation specific to migraine headache.
Lancet 357(9261):1016-7, 2001.
PMID: 11293599.
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| Our findings provide evidence that migraine involves the
brainstem, and show several areas involved in cluster headaches | A. Bahra; M. S. Matharu; Christian Büchel; Richard S. J. Frackowiak; P. J. Goadsby. Brainstem activation specific to migraine headache.
Lancet 357(9261):1016-7, 2001.
PMID: 11293599.
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| To achieve
this, we used functional magnetic resonance imaging (fMRI) to measure
brain activity when human observers viewed freely dynamic natural scenes
(a James Bond movie) | Andreas Bartels; Semir Zeki. Functional brain mapping during free viewing of natural scenes.
Human Brain Mapping 21(2):75-85, 2004.
PMID: 14755595.
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| Our method thus
opens a new way of brain mapping, which allows the localization of a
multitude of brain areas based on a single experiment using uncontrolled,
natural stimuli | Andreas Bartels; Semir Zeki. Functional brain mapping during free viewing of natural scenes.
Human Brain Mapping 21(2):75-85, 2004.
PMID: 14755595.
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WOBIB: 123.
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| We are of the opinion
that stage-1 sleep represents the dreaming state of wakefulness, while
rapid eye movement (REM) sleep reflects the dreaming state of the unaware,
sleeping brain | Troels W. Kjaer; Ian Law; Gordon Wiltschiotz; Olaf B. Paulson; Peter L. Madsen. Regional cerebral blood flow during light sleep--a H(2)(15)O-PET study.
Journal of Sleep Research 11(3):201-207, 2002.
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| AIMS: Sedation induced by antihistamines is widely recognized to be caused by their penetration through the blood-brain-barrier and the consequent occupation of brain histamine H1-receptors | M. Tagawa; M. Kano; N. Okamura; M. Higuchi; M. Matsuda; Y. Mizuki; H. Arai; R. Iwata; T. Fujii; S. Komemushi; T. Ido; M. Itoh; H. Sasaki; T. Watanabe; K. Yanai. Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine.
British Journal of Clinical Pharmacology 52(5):501-509, 2001.
PMID: 11736858.
WOBIB: 127.
|
| The binding potential of doxepin (BP = Bmax/Kd) for available brain H1-receptors was imaged on a voxel-by-voxel basis through graphical analysis | M. Tagawa; M. Kano; N. Okamura; M. Higuchi; M. Matsuda; Y. Mizuki; H. Arai; R. Iwata; T. Fujii; S. Komemushi; T. Ido; M. Itoh; H. Sasaki; T. Watanabe; K. Yanai. Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine.
British Journal of Clinical Pharmacology 52(5):501-509, 2001.
PMID: 11736858.
WOBIB: 127.
|
| CONCLUSIONS: Ebastine (10 mg orally) causes brain histamine H1-receptor occupation of approximately 10%, consistent with its lower incidence of sedative effect, whereas (+)-chlorpheniramine occupied about 50% of brain H1-receptors even at a low but sedative dose of 2 mg; occupancy of (+)-chlorpheniramine was correlated with plasma (+)-chlorpheniramine concentration | M. Tagawa; M. Kano; N. Okamura; M. Higuchi; M. Matsuda; Y. Mizuki; H. Arai; R. Iwata; T. Fujii; S. Komemushi; T. Ido; M. Itoh; H. Sasaki; T. Watanabe; K. Yanai. Neuroimaging of histamine H1-receptor occupancy in human brain by positron emission tomography (PET): a comparative study of ebastine, a second-generation antihistamine, and (+)-chlorpheniramine, a classical antihistamine.
British Journal of Clinical Pharmacology 52(5):501-509, 2001.
PMID: 11736858.
WOBIB: 127.
|
| It is not known which brain processes depend upon the successful integration of visual and proprioceptive information and are therefore impaired when these modalities disagree | Daniela Balslev; Finn Årup Nielsen; Olaf B. Paulson; Ian Law. Right Temporoparietal Cortex Activation during Visuo-proprioceptive Conflict.
Cerebral Cortex 15(2):166-169, 2004.
PMID: 15238438.
DOI: 10.1093/cercor/bhh119.
WOBIB: 128.
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| With fMRI in healthy subjects we compared brain activity across two conditions with similar visual and proprioceptive stimulation and similar task demands that differed by the congruence of movement showed by the two modalities | Daniela Balslev; Finn Årup Nielsen; Olaf B. Paulson; Ian Law. Right Temporoparietal Cortex Activation during Visuo-proprioceptive Conflict.
Cerebral Cortex 15(2):166-169, 2004.
PMID: 15238438.
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| The effect of stimulus rate and its interaction with stimulus type on brain activity during reading was investigated using functional magnetic resonance imaging (fMRI) | Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI.
Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000.
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| This (i) enabled the segregation of brain regions showing differential responses, (ii) identified the optimum experimental design parameters for maximizing sensitivity, and (iii) allowed us to evaluate further the sources of discrepancy between positron emission tomography (PET) and fMRI signals | Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI.
Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000.
PMID: 11506654.
DOI: 10.1162/089892900564000.
FMRIDCID: 2-2000-11189.
WOBIB: 129.
|
| The analysis specifically identified regions showing (i) an effect of stimulus rate on brain activity during reading; (ii) modulation of this effect by word type; and (iii) increased activity during reading relative to rest, but with no dependence on stimulus rate | Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI.
Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000.
PMID: 11506654.
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FMRIDCID: 2-2000-11189.
WOBIB: 129.
|
| RESULTS: Brain regions in which activity was significantly correlated with tic occurrence in the group included medial and lateral premotor cortices, anterior cingulate cortex, dorsolateral-rostral prefrontal cortex, inferior parietal cortex, putamen, and caudate, as well as primary motor cortex, the Broca's area, superior temporal gyrus, insula, and claustrum | E. Stern; D. A. Silbersweig; K. Y. Chee; Andrew Holmes; M. M. Robertson; M. Trimble; Christopher D. Frith; Richard S. J. Frackowiak; Raymond J. Dolan. A functional neuroanatomy of tics in Tourette syndrome.
Archives of General Psychiatry 57(8):741-748, 2000.
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| This study applied positron emission tomography (PET) to investigate the brain serotonin 2A (5HT2A) receptor, which could contribute to disturbances of appetite and behavior in AN | Guido K. Frank; Walter H. Kaye; Carolyn C. Meltzer; Julie C. Price; Phil Greer; Claire McConaha; Kelli Skovira. Reduced 5-HT2A receptor binding after recovery from anorexia nervosa.
Biological Psychiatry 52(9):896-906, 2002.
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| Moreover, due to the large size of the sample voxelwise statistical testing was possible to objectively estimate which brain regions are more frequently compromised in neglect patients relative to patients without neglect | Hans-Otto Karnath; Monika Fruhmann Berger; Wilhelm Kuker; Chris Rorden. The Anatomy of Spatial Neglect based on Voxelwise Statistical Analysis: A Study of 140 Patients.
Cerebral Cortex 14(10):1164-1172, 2004.
PMID: 15142954.
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| To understand spatial summation of pain processing in the brain, we investigated the cerebral evoked responses to non-painful and painful contact heat stimulation (70 degrees C/s fast onset; intensity 2,4,6, corresponding to the individual's non-, slight and moderate pain) comparing one (1s) vs | Andrew C. N. Chen; David M. Niddam; Helen J. Crawford; Robert Oostenveld; Lars Arendt-Nielsen. Spatial summation of pain processing in the human brain as assessed by cerebral event related potentials.
Neuroscience Letters 328(2):190-194, 2002.
PMID: 12133585.
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| The positive correlations in mainly posterior brain regions indicate that normal aging is associated with an increase in metabolism after citalopram administration, whereas the negative correlations in mainly anterior brain regions indicate that normal aging is associated with a greater decrease in metabolism | Sara Goldberg; Gwenn S. Smith; Anna Barnes; Yilong Ma; Elisse Kramer; Kimberly Robeson; Margaret Kirshner; Bruce G. Pollock; David Eidelberg. Serotonin modulation of cerebral glucose metabolism in normal aging.
Neurobiology of Aging 25(2):167-174, 2004.
PMID: 14749134.
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| These results suggest different compensatory processes in anterior compared to posterior brain regions secondary to the age-related loss of serotonin innervation | Sara Goldberg; Gwenn S. Smith; Anna Barnes; Yilong Ma; Elisse Kramer; Kimberly Robeson; Margaret Kirshner; Bruce G. Pollock; David Eidelberg. Serotonin modulation of cerebral glucose metabolism in normal aging.
Neurobiology of Aging 25(2):167-174, 2004.
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| The striate cortex
(V1) and the contiguous visual area (V2), which in the monkey
brain feed both the homologous areas, were active in all 4
conditions | Semir Zeki; J. D. Watson; C. J. Lueck; Karl J. Friston; C. Kennard; Richard S. J. Frackowiak. A direct demonstration of functional specialization in human visual cortex.
Journal of Neuroscience 11(3):641-649, 1991.
PMID: 2002358.
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| This is
based on an hypothesis-led analysis of the covariance structure of
the blood flow maps and promises to be a powerful tool for
inferring anatomical pathways in the normal human brain | Semir Zeki; J. D. Watson; C. J. Lueck; Karl J. Friston; C. Kennard; Richard S. J. Frackowiak. A direct demonstration of functional specialization in human visual cortex.
Journal of Neuroscience 11(3):641-649, 1991.
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| Studies of delayed nonmatching-to-sample (DNMS) performance following lesions of the monkey cortex have revealed a critical circuit of brain regions involved in forming memories and retaining and retrieving stimulus representations | Greig I. de Zubicaray; Katie McMahon; Stephen J. Wilson; Santhi Muthiah. Brain activity during the encoding, retention, and retrieval of stimulus representations.
Learning & Memory 8(5):243-251, 2001.
PMID: 11584070.
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| Using event-related functional magnetic resonance imaging (fMRI), we measured brain activity in 10 healthy human participants during performance of a trial-unique visual DNMS task using novel barcode stimuli | Greig I. de Zubicaray; Katie McMahon; Stephen J. Wilson; Santhi Muthiah. Brain activity during the encoding, retention, and retrieval of stimulus representations.
Learning & Memory 8(5):243-251, 2001.
PMID: 11584070.
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| Several brain regions identified by monkey studies as being important for successful DNMS performance showed selective activity during the different phases, including the mediodorsal thalamic nucleus (encoding), ventrolateral prefrontal cortex (retention), and perirhinal cortex (retrieval) | Greig I. de Zubicaray; Katie McMahon; Stephen J. Wilson; Santhi Muthiah. Brain activity during the encoding, retention, and retrieval of stimulus representations.
Learning & Memory 8(5):243-251, 2001.
PMID: 11584070.
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WOBIB: 141.
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| The present study shows the utility of investigating performance on tasks derived from animal models to assist in the identification of brain regions involved in human recognition memory | Greig I. de Zubicaray; Katie McMahon; Stephen J. Wilson; Santhi Muthiah. Brain activity during the encoding, retention, and retrieval of stimulus representations.
Learning & Memory 8(5):243-251, 2001.
PMID: 11584070.
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| Regional cerebral blood flow (rCBF) and blood oxygenation level-dependent (BOLD) contrasts represent different physiological measures of brain activation | Ulrich Schall; Patrick Johnston; Jim Lagopoulos; Markus Juptner; Walter Jentzen; Renate Thienel; Alexandra Dittmann-Balcar; Stefan Bender; Philip B. Ward. Functional brain maps of Tower of London performance: a positron emission tomography and functional magnetic resonance imaging study.
NeuroImage 20(2):1154-61, 2003.
PMID: 14568484.
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| The present study aimed to compare two functional brain imaging techniques (functional magnetic resonance imaging versus [(15)O] positron emission tomography) when using Tower of London (TOL) problems as the activation task | Ulrich Schall; Patrick Johnston; Jim Lagopoulos; Markus Juptner; Walter Jentzen; Renate Thienel; Alexandra Dittmann-Balcar; Stefan Bender; Philip B. Ward. Functional brain maps of Tower of London performance: a positron emission tomography and functional magnetic resonance imaging study.
NeuroImage 20(2):1154-61, 2003.
PMID: 14568484.
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WOBIB: 144.
|
| These results imply consistency across the two neuroimaging modalities, particularly for the assessment of prefrontal brain function when using a parametric TOL adaptation | Ulrich Schall; Patrick Johnston; Jim Lagopoulos; Markus Juptner; Walter Jentzen; Renate Thienel; Alexandra Dittmann-Balcar; Stefan Bender; Philip B. Ward. Functional brain maps of Tower of London performance: a positron emission tomography and functional magnetic resonance imaging study.
NeuroImage 20(2):1154-61, 2003.
PMID: 14568484.
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| Previous functional brain imaging studies suggest that the ability to infer the intentions and mental states of others (social cognition) is mediated by medial prefrontal cortex | T. F. Farrow; Y. Zheng; I. D. Wilkinson; S. A. Spence; J. F. Deakin; N. Tarrier; P. D. Griffiths; P. W. Woodruff. Investigating the functional anatomy of empathy and forgiveness.
NeuroReport 12(11):2433-2438, 2001.
PMID: 11496124.
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| We used functional MRI to detect brain regions engaged by judging others' emotional states and the forgivability of their crimes | T. F. Farrow; Y. Zheng; I. D. Wilkinson; S. A. Spence; J. F. Deakin; N. Tarrier; P. D. Griffiths; P. W. Woodruff. Investigating the functional anatomy of empathy and forgiveness.
NeuroReport 12(11):2433-2438, 2001.
PMID: 11496124.
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| Empathic and forgivability judgements activate specific regions of the human brain, which we propose contribute to social cohesion | T. F. Farrow; Y. Zheng; I. D. Wilkinson; S. A. Spence; J. F. Deakin; N. Tarrier; P. D. Griffiths; P. W. Woodruff. Investigating the functional anatomy of empathy and forgiveness.
NeuroReport 12(11):2433-2438, 2001.
PMID: 11496124.
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| We used event-related functional magnetic-resonance imaging (fMRI) to identify brain regions responsive to changes in visual, auditory and tactile stimuli | J. Downar; A. P. Crawley; D. J. Mikulis; K. D. Davis. A multimodal cortical network for the detection of changes in the sensory environment.
Nature Neuroscience 3(3):277-283, 2000.
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| Personality traits are a variance of behavioral patterns among individuals and may reflect a variance of brain activity, but their neurobiological explanation is still a matter of debate | Motoaki Sugiura; Ryuta Kawashima; Manabu Nakagawa; Ken Okada; Tachio Sato; Ryoi Goto; Kazunori Sato; Shuichi Ono; Torsten Schormann; Karl Zilles; Hiroshi Fukuda. Correlation between human personality and neural activity in cerebral cortex.
NeuroImage 11(5 Pt 1):541-546, 2000.
PMID: 10806039.
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| To explore the relationship between individual differences in negative affect (NA) and brain activity, we asked healthy subjects participating in positron-emission tomography scans to rate the extent to which they had experienced NA terms during the month before scanning | David H. Zald; Dorothy L. Mattson; Jose V. Pardo. Brain activity in ventromedial prefrontal cortex correlates with individual differences in negative affect.
Proc Natl Acad Sci U S A 99(4):2450-2454, 2002.
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| Brain activations to matched and mismatched audio-visual inputs were contrasted with the combined response to both unimodal conditions | Gemma A. Calvert; Ruth Campbell; Michael J. Brammer. Evidence from functional magnetic resonance imaging of crossmodal binding in the human heteromodal cortex.
Current Biology 10(11):649-657, 2000.
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| It has been suggested that, in the clinical context of emotional blunting, there is a shift in the relative contribution of brain regions subserving cognitive and emotional processing | Kathryn M. Abel; Matthew P. G. Allin; Katarzyna Kucharska-Pietura; Anthony S. David; Chris Andrew; Steven C. R. Williams; Michael J. Brammer; Mary L. Phillips. Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study.
NeuroReport 14(3):387-391, 2003.
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| Thus, we predicted that ketamine would produce reduced activity in limbic and visual brain regions involved in emotion processing, and increased activity in dorsal regions of the prefrontal cortex and cingulate gyrus, both associated with cognitive processing and, putatively, with emotion regulation | Kathryn M. Abel; Matthew P. G. Allin; Katarzyna Kucharska-Pietura; Anthony S. David; Chris Andrew; Steven C. R. Williams; Michael J. Brammer; Mary L. Phillips. Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study.
NeuroReport 14(3):387-391, 2003.
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| These results suggest that sadness and happiness may be associated with similar brain regions but distinct sub-regions and neural circuits | Mario Pelletier; Alain Bouthillier; Johanne Levesque; Serge Carrier; Claude Breault; Vincent Paquette; Boualem Mensour; Jean-Maxime Leroux; Gilles Beaudoin; Pierre Bourgouin; Mario Beauregard. Separate neural circuits for primary emotions? Brain activity during self-induced sadness and happiness in professional actors.
NeuroReport 14(8):1111-1116, 2003.
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| The results complement and extend previous data implicating these regions in olfactory processing, and indicate that a functional asymmetry exists in the human brain favouring the right orbitofrontal area in olfaction | Robert J. Zatorre; Marilyn Jones-Gotman; Alan C. Evans; Ernst Meyer. Functional localization and lateralization of human olfactory cortex.
Nature 360(6402):339-340, 1992.
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| Patients with amnesia have gross impairments of episodic memory while other kinds of memory remain intact, suggesting that a separable brain system underlies episodic memory | Tim Shallice; Paul Fletcher; Chris D. Frith; Paul Grasby; Richard S. J. Frackowiak; Raymond J. Dolan. Brain regions associated with acquisition and retrieval of verbal episodic memory.
Nature 368(6472):633-635, 1994.
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| A dual-task interference paradigm was used to isolate brain areas associated with acquisition, and a cueing paradigm to isolate the areas concerned with retrieval from verbal episodic memory | Tim Shallice; Paul Fletcher; Chris D. Frith; Paul Grasby; Richard S. J. Frackowiak; Raymond J. Dolan. Brain regions associated with acquisition and retrieval of verbal episodic memory.
Nature 368(6472):633-635, 1994.
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| We examined the relation between extrastriatal dopamine D2 receptor binding in living human brain and the personality trait of novelty seeking that has been proposed to be related to dopaminergic function in the brain | T. Suhara; F. Yasuno; Y. Sudo; M. Yamamoto; M. Inoue; Y. Okubo; K. Suzuki. Dopamine D2 receptors in the insular cortex and the personality trait of novelty seeking.
NeuroImage 13(5):891-895, 2001.
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| The dissociation between regions activated by olfactory exploration (sniffing) and regions activated by olfactory content (smell) shows a distinction in brain organization in terms of human olfaction | Noam Sobel; V. Prabhakaran; John E. Desmond; Gary H. Glover; R. L. Goode; Edith V. Sullivan; John D. E. Gabrieli. Sniffing and smelling: separate subsystems in the human olfactory cortex.
Nature 392(6673):282-286, 1998.
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| A much debated question is whether sex differences exist
in the functional organization of the brain for language | Bennett A. Shaywitz; Sally E. Shaywitz; Kenneth R. Pugh; R. Todd Constable; Pawl Skudlawski; Robert K. Fulbright; Richard A. Bronen; Jack M. Fletcher; Donald P. Shankwiler; Leonard Katz; John C. Gore. Sex differences in the functional organization of the brain for language.
Nature 373(6515):607-609, 1995.
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| During phonological tasks, brain activation in males is
lateralized to the left inferior frontal gyrus regions; in females
the pattern of activation is very different, engaging more diffuse
neural systems that involve both the left and right inferior
frontal gyrus | Bennett A. Shaywitz; Sally E. Shaywitz; Kenneth R. Pugh; R. Todd Constable; Pawl Skudlawski; Robert K. Fulbright; Richard A. Bronen; Jack M. Fletcher; Donald P. Shankwiler; Leonard Katz; John C. Gore. Sex differences in the functional organization of the brain for language.
Nature 373(6515):607-609, 1995.
PMID: 7854416.
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|
| Our data provide clear evidence for a sex
difference in the functional organization of the brain for
language and indicate that these variations exist at the level of
phonological processing | Bennett A. Shaywitz; Sally E. Shaywitz; Kenneth R. Pugh; R. Todd Constable; Pawl Skudlawski; Robert K. Fulbright; Richard A. Bronen; Jack M. Fletcher; Donald P. Shankwiler; Leonard Katz; John C. Gore. Sex differences in the functional organization of the brain for language.
Nature 373(6515):607-609, 1995.
PMID: 7854416.
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| The present paper reports a functional neuroimaging study with positron emission tomography in which we studied brain activity in normal volunteers while they performed story comprehension tasks necessitating the attribution of mental states | Paul C. Fletcher; F Happe; Uta Frith; S. C. Baker; Raymond J. Dolan; Richard S. J. Frackowiak; Chris D. Frith. Other minds in the brain: a functional imaging study of "theory of mind" in story comprehension.
Cognition 57(2):109-128, 1995.
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| The resultant brain activity was compared with that measured in two control tasks: "physical" stories which did not require this mental attribution, and passages of unlinked sentences | Paul C. Fletcher; F Happe; Uta Frith; S. C. Baker; Raymond J. Dolan; Richard S. J. Frackowiak; Chris D. Frith. Other minds in the brain: a functional imaging study of "theory of mind" in story comprehension.
Cognition 57(2):109-128, 1995.
PMID: 8556839.
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| These surprisingly clear-cut findings are discussed in relation to previous studies of brain activation during story comprehension | Paul C. Fletcher; F Happe; Uta Frith; S. C. Baker; Raymond J. Dolan; Richard S. J. Frackowiak; Chris D. Frith. Other minds in the brain: a functional imaging study of "theory of mind" in story comprehension.
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| The localisation of brain regions involved in normal attribution of mental states and contextual problem solving is feasible and may have implications for the neural basis of autism | Paul C. Fletcher; F Happe; Uta Frith; S. C. Baker; Raymond J. Dolan; Richard S. J. Frackowiak; Chris D. Frith. Other minds in the brain: a functional imaging study of "theory of mind" in story comprehension.
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| Functional magnetic resonance imaging (fMRI) was used to examine how the brain responds to temporal compression of speech and to determine whether the same regions are also involved in phonological processes associated with reading | Russell A. Poldrack; Elise Temple; Athanassios Protopapas; Srikantan Nagarajan; Paula Tallal; Michael Merzenich; John D. E. Gabrieli. Relations Between the Neural Bases of Dynamic Auditory Processing and Phonological Processing: Evidence from fMRI.
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| In the brain mapping literature, it remains unsolved as to whether there are separate brain regions mediating the processing of syllables and phonemes | Wai Ting Soik; Zhen Jin; Paul Fletcher; Li Hai Tan. Distinct brain regions associated with syllable and phoneme.
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| CONCLUSIONS: While this study should be considered preliminary, it identifies regions of the brain that participate in happiness, sadness, and disgust, regions that distinguish between positive and negative emotions, and regions that depend on both the elicitor and valence of emotion or their interaction | Richard D. Lane; Eric M. Reiman; Geoffrey L. Ahern; Gary E. Schwartz; Richard J. Davidson. Neuroanatomical Correlates of Happiness, Sadness, and Disgust.
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| The nascent field of neuroeconomics seeks to ground economic decisionmaking in the biological substrate of the brain | Alan G. Sanfey; James K. Rilling; Jessica A. Aronson; Leigh E. Nystrom; Jonathan D. Cohen. The Neural Basis of Economic decision-Making in the Ultimatum Game.
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| Unfair offers elicited activity in brain areas related to both emotion (anterior insula) and cognition (dorsolateral prefrontal cortex) | Alan G. Sanfey; James K. Rilling; Jessica A. Aronson; Leigh E. Nystrom; Jonathan D. Cohen. The Neural Basis of Economic decision-Making in the Ultimatum Game.
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| Magnetic resonance imaging (MRI) studies suggest that significant changes in gray matter density occur during adolescence because of brain maturation | Sophia Frangou; Xavier Chitins; Steven C. R. Williams. Mapping IQ and gray matter density in healty young people.
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| These findings suggest that general intellectual ability in healthy young people is related to specific brain regions known to be involved in the executive control of attention, working memory, and response selection | Sophia Frangou; Xavier Chitins; Steven C. R. Williams. Mapping IQ and gray matter density in healty young people.
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| Two retrieval tasks, episodic and semantic, were crossed with episodic (old/new) and semantic (living/nonliving) properties of individual items to yield evidence of regional brain activity associated with task-related processes, item-related processes, and their interaction | Emrah Düzel; Roberto Cabeza; Terence W. Picton; Andrew P. Yonelinas; Henning Scheich; Hans-Jochen Heinze; Endel Tulving. Task-related and item-related brain processes of memory retrieval.
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| The results provide converging hemodynamic and electrophysiological evidence for the distinction of task- and item-related processes, show that they map onto spatially and temporally distinct patterns of brain activity, and clarify the hemispheric encoding/retrieval asymmetry (HERA) model of prefrontal encoding and retrieval asymmetry | Emrah Düzel; Roberto Cabeza; Terence W. Picton; Andrew P. Yonelinas; Henning Scheich; Hans-Jochen Heinze; Endel Tulving. Task-related and item-related brain processes of memory retrieval.
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| Parts of the limbic system associated
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| USING functional magnetic resonance imaging (fMRI), we mapped brain activity in six normal volunteers during two silent verbal fluency tasks, one with a phonemic (letter) cue and one with a semantic (category) cue | Eraldo Paulesu; Ben Goldacre; Paola Scifo; Stefano F. Cappa; Maria Carla Gilardi; Isabella Castiglioni; Daniela Perani; Frruccio Fazio. Functional heterogeneity of left inferior frontal cortex as revealed by fMRI.
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| An association between the brain evoked response potentials and lying on the GKT suggests that deception may be associated with changes in other measures of brain activity such as regional blood flow that could be anatomically localized with event-related functional magnetic resonance imaging (fMRI) | Daniel D. Langleben; L. Schroeder; J. A. Maldjian; R. C. Gur; S. McDonald; J. D. Ragland; C. P. O'Brien; A. R. Childress. Brain Activity during Simulated Deception: An Event-Related Functional Magnetic Resonance Study.
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