WOEXP: 390 - Increased benzodiazepine receptor binding in panic disorder
 
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Increased benzodiazepine receptor binding in panic disorder. Increased benzodiazepine receptor binding in panic disorder in panic disorder patients versus normal control subjects. WOEXP: 390.

J. D. Bremner; R. B. Innis; T. White; M. Fujita; D. Silbersweig; A. W. Goddard; L. Staib; E. Stern; A. Cappiello; S. Woods; R. Baldwin; D. S. Charney. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 47(2):96-106, 2000. PMID: 10664825. WOBIB: 126.

Disease - Panic disorder
WOEXT: 234.
WOEXT: 380.

Modality:SPECT/MRI
Measured variable: Distribution volume
Tracer: I-123 Iomazenil
Scanner: Digital Scintigraphics CERASPECT
Number of subjects: 29

Asymmetry: -0.27344 (left: -1, right: +1)

  x     y     z   Lobar anatomy Functional area WOROI Value
-16 -1 18 Right caudate      
-18 -75 18 Cuneus (occipital cortex)      
34 29 28 Right middle frontal gyrus      
-44 -41 2 Left middle temporal gyrus      
-48 -69 15   Visual association    
24 -97 1   Visual association    
28 -87 15        

corner cube of volume 390 (Increased benzodiazepine receptor binding in panic disorder)

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Related - positive correlated volumes

+1: 1.00000 Increased benzodiazepine receptor binding in panic disorder. Increased benzodiazepine receptor binding in panic disorder in panic disorder patients versus normal control subjects. WOEXP: 390.
J. D. Bremner; R. B. Innis; T. White; M. Fujita; D. Silbersweig; A. W. Goddard; L. Staib; E. Stern; A. Cappiello; S. Woods; R. Baldwin; D. S. Charney. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 47(2):96-106, 2000. PMID: 10664825. WOBIB: 126.

+2: 0.48239 Visuospatial stimulus, pooled data. Viewing of dots in one of four displayed boxes versus rest. WOEXP: 351.
B. J. Casey; Jonathan D. Cohen; K. O'Craven; Richard J. Davidson; W. Irwin; C. A. Nelson; D. C. Noll; X. Hu; M. J. Lowe; B. R. Rosen; C. L. Truwitt; P. A. Turski. Reproducibility of fMRI results across four institutions using a spatial working memory task. NeuroImage 8(3):249-261, 1998. PMID: 9758739. FMRIDCID: . WOBIB: 116.

+3: 0.40421 Various visual motion stimuli. Various first and second order motion stimuli versus stationary visual stimuli. WOEXP: 175.
A. T. Smith; M. W. Greenlee; K. D. Singh; F. M. Kraemer; J. Hennig. The processing of first- and second-order motion in human visual cortex assessed by functional magnetic resonance imaging (fMRI). Journal of Neuroscience 18(10):3816-30, 1998. PMID: 9570811. WOBIB: 53.

+4: 0.40314 Alzheimer's disease versus healthy. Patients with Alzheimer's disease in mental resting state versus matched healthy controls. WOEXP: 291.
Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. American Journal of Psychiatry 159(5):738-45, 2002. PMID: 11986126. WOBIB: 91.

+5: 0.39199 Resting (group II). Awake resting state with eyes closed versus goal-directed task. WOEXP: 179.
Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function. Proc Natl Acad Sci U S A 98(2):676-82, 2001. PMID: 11209064. DOI: 10.1073/pnas.98.2.676. WOBIB: 55.

+6: 0.39106 Dynamic complex visual scene. Passive viewing and hearing of a movie (James Bond, Tomorrow never dies) with changes from color to black and white every 30 seconds and interrupted every 2.5 or 3 minutes with a blank period. Areas with high loadings in an independent component analysis.. WOEXP: 174.
Semir Zeki; R. J. Perry; A. Bartels. The processing of kinetic contours in the brain. Cerebral Cortex 13(2):189-202, 2003. PMID: 12507950. WOBIB: 52.

+7: 0.39096 Large line patterns. One-back match-to-sample task with large line patterns versus small line patterns. WOEXP: 101.
A. Larsen; C. Bundesen; S. Kyllingsbaek; O. B. Paulson; I. Law. Brain activation during mental transformation of size. Journal of Cognitive Neuroscience 12(5):763-74, 2000. PMID: 11054919. WOBIB: 30.

+8: 0.38225 Kinetic boundaries. Visual motion of dots with boundaries versus coherent visual motion of dots. WOEXP: 113.
E. Grossman; M. Donnelly; R. Price; D. Pickens; V. Morgan; G. Neighbor; R. Blake. Brain areas involved in perception of biological motion. Journal of Cognitive Neuroscience 12(5):711-20, 2000. PMID: 11054914. WOBIB: 33.

+9: 0.36572 Holistic integration. Holistic integration of visual elements to perceptual wholes (single objects). WOEXP: 14.
Christian Gerlach; C. T. Aaside; G. W. Humphreys; Anders Gade; O. B. Paulson; I. Law. Brain activity related to integrative processes in visual object recognition: bottom-up integration and the modulatory influence of stored knowledge. Neuropsychologia 40(8):1254-67, 2002. PMID: 11931928. WOBIB: 7.

+10: 0.34904 Audio-visual speech with high congruent and low ingruent response. Heard speech and lip movements with supra-additive response to congruent signals and sub-additive response to incongruent signals. WOEXP: 472.
Gemma A. Calvert; Ruth Campbell; Michael J. Brammer. Evidence from functional magnetic resonance imaging of crossmodal binding in the human heteromodal cortex. Current Biology 10(11):649-657, 2000. PMID: 10837246. FMRIDCID: . WOBIB: 154.

+11: 0.33844 Classifying visually presented nouns. Deciding whether visually presented concrete nouns symbolized living or nonliving objects and rehearsing the decision subvocally versus viewing a isoluminant screen. WOEXP: 345.
E. T. Bullmore; S. Rabe-Hesketh; R. G. Morris; Steven C. R. Williams; L. Gregory; J. A. Gray; M. J. Brammer. Functional magnetic resonance image analysis of a large-scale neurocognitive network. NeuroImage 4(1):16-33, 1996. PMID: 9345494. WOBIB: 113.

+12: 0.33410 Motion verb sentences versus meaningless sentences. Hearing motion verb sentences and button press response versus hearing meaningless sentences. WOEXP: 535.
Mikkel Wallentin; Torben Ellegaard Lund; Svend Østergaard; Leif Østergaard; Andreas Roepstorff. Motion verb sentences activate left posterior middle temporal cortex despite static context. NeuroReport 16(5):649-652, 2005. PMID: 15812326. FMRIDCID: . WOBIB: 175.

+13: 0.33410 Static verb sentences versus meaningless sentences. Hearing static verb sentences and button press response versus hearing meaningless sentences. WOEXP: 536.
Mikkel Wallentin; Torben Ellegaard Lund; Svend Østergaard; Leif Østergaard; Andreas Roepstorff. Motion verb sentences activate left posterior middle temporal cortex despite static context. NeuroReport 16(5):649-652, 2005. PMID: 15812326. FMRIDCID: . WOBIB: 175.

+14: 0.32898 Moving dots versus stationary dots. 250 white dots moved radially from the fixation point in the middle of the screen in random directions towards the border of the screen. WOEXP: 76.
Christian Büchel; Oliver Josephs; Geraint Rees; R. Turner; C. D. Frith; Karl J. Friston. The functional anatomy of attention to visual motion. A functional MRI study. Brain 121 ( Pt 7):1281-94, 1998. PMID: 9679780. WOBIB: 24.

+15: 0.32639 Word rate dependence in silent reading of proper words. Word rate dependence in silent reading of visually presented proper words. WOEXP: 400.
Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI. Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000. PMID: 11506654. DOI: 10.1162/089892900564000. FMRIDCID: 2-2000-11189. WOBIB: 129.

+16: 0.32230 Silent reading of proper words versus rest. Silent reading of visually presented proper words versus resting. WOEXP: 395.
Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI. Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000. PMID: 11506654. DOI: 10.1162/089892900564000. FMRIDCID: 2-2000-11189. WOBIB: 129.

+17: 0.31959 Recognizable visual objects. Recognizable visual objects versus unrecognizable. WOEXP: 15.
Christian Gerlach; C. T. Aaside; G. W. Humphreys; Anders Gade; O. B. Paulson; I. Law. Brain activity related to integrative processes in visual object recognition: bottom-up integration and the modulatory influence of stored knowledge. Neuropsychologia 40(8):1254-67, 2002. PMID: 11931928. WOBIB: 7.

+18: 0.31888 Word rate dependence in silent reading of pseudowords. Word rate dependence in silent reading of visually presented pseudowords. WOEXP: 401.
Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI. Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000. PMID: 11506654. DOI: 10.1162/089892900564000. FMRIDCID: 2-2000-11189. WOBIB: 129.

+19: 0.31818 Word rate dependence in silent reading. Word rate dependence in silent reading of visually presented proper words and pseudowords. WOEXP: 399.
Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI. Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000. PMID: 11506654. DOI: 10.1162/089892900564000. FMRIDCID: 2-2000-11189. WOBIB: 129.

+20: 0.31719 Visual exploration versus saccades. Visual search exploration versus saccade eye movement. WOEXP: 6.
Darren R. Gitelman; Todd B. Parrish; Karl J. Friston; M-Marsel Mesulam. Functional anatomy of visual search: regional segregations within the frontal eye fields and effective connectivity of the superior colliculus. NeuroImage 15(4):970-82, 2002. PMID: 11906237. DOI: 10.1006/nimg.2001.1006. WOBIB: 3.

+21: 0.31628 Silent reading of pseudowords versus rest. Silent reading of visually pseudowords versus resting. WOEXP: 396.
Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI. Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000. PMID: 11506654. DOI: 10.1162/089892900564000. FMRIDCID: 2-2000-11189. WOBIB: 129.

+22: 0.31523 Resting (group I). Awake resting state with eyes closed versus goal-directed task. WOEXP: 178.
Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function. Proc Natl Acad Sci U S A 98(2):676-82, 2001. PMID: 11209064. DOI: 10.1073/pnas.98.2.676. WOBIB: 55.

+23: 0.30616 Color shape and motion shape (group data). Passive viewing of color shape from static isoluminant red and green oriented bars and stationary shapes by kinetic contours from motion of fields of dots versus no shape color viewing and no shape coherent visual motion. WOEXP: 172.
Semir Zeki; R. J. Perry; A. Bartels. The processing of kinetic contours in the brain. Cerebral Cortex 13(2):189-202, 2003. PMID: 12507950. WOBIB: 52.

+24: 0.29837 Obsessive compulsive disorder, negative correlation. Negative correlation with obsessive compulsive disorder symptom intensities while contaminants placed in folded hands. WOEXP: 324.
Philip K. McGuire; C. J. Bench; C. D. Frith; I. M. Marks; Richard S. J. Frackowiak; R. J. Dolan. Functional anatomy of obsessive-compulsive phenomena. British Journal of Psychiatry 164(4):459-468, 1994. PMID: 8038933. WOBIB: 104.

+25: 0.29658 Frontal head versus deviated head. Determine gender and press button based on photographs of young adults with neutral expressions full face frontal and rotated 30 degrees and with directed and averted gaze. WOEXP: 52.
N. George; J. Driver; R. J. Dolan. Seen gaze-direction modulates fusiform activity and its coupling with other brain areas during face processing. NeuroImage 13(6 Pt 1):1102-12, 2001. PMID: 11352615. DOI: 10.1006/nimg.2001.0769. WOBIB: 18.


Antirelated - negatively correlated volumes

-1: -0.06322 Happy versus neutral. Recalling of powerful and personal autobiographical emotional episodes invoking happiness versus recalling emotionally neutral life episodes. WOEXP: 484.
Mario Pelletier; Alain Bouthillier; Johanne Levesque; Serge Carrier; Claude Breault; Vincent Paquette; Boualem Mensour; Jean-Maxime Leroux; Gilles Beaudoin; Pierre Bourgouin; Mario Beauregard. Separate neural circuits for primary emotions? Brain activity during self-induced sadness and happiness in professional actors. NeuroReport 14(8):1111-1116, 2003. PMID: 12821792. DOI: 10.1097/01.wnr.0000075421.59944.69. FMRIDCID: . WOBIB: 157.

-2: -0.06311 Sad versus neutral. Recalling of powerful and personal autobiographical emotional episodes invoking sadness versus recalling emotionally neutral life episodes. WOEXP: 483.
Mario Pelletier; Alain Bouthillier; Johanne Levesque; Serge Carrier; Claude Breault; Vincent Paquette; Boualem Mensour; Jean-Maxime Leroux; Gilles Beaudoin; Pierre Bourgouin; Mario Beauregard. Separate neural circuits for primary emotions? Brain activity during self-induced sadness and happiness in professional actors. NeuroReport 14(8):1111-1116, 2003. PMID: 12821792. DOI: 10.1097/01.wnr.0000075421.59944.69. FMRIDCID: . WOBIB: 157.

-3: -0.06170 High visual orientation working memory maintenance. Maintenance of 6 serial presented oriented visual gratings in working memory and responding to a cue by pressing a key with either left or right hand versus pressing a key with either left or right hand depending on orientation of visual grating. WOEXP: 170.
L. Cornette; P. Dupont; E. Salmon; G. A. Orban. The neural substrate of orientation working memory. Journal of Cognitive Neuroscience 13(6):813-28, 2001. PMID: 11564325. DOI: 10.1162/08989290152541476. WOBIB: 51.

-4: -0.05574 Novel word recall versus practiced word recall. Speak load words recalled from a list of 15 words heard only one time just prior to recall versus speak words aloud from a list of practiced words. WOEXP: 275.
Nancy C. Andreasen; D. S. O'Leary; T. Cizadlo; Stephan Arndt; K. Rezai; G. L. Watkins; L. L. Ponto; R. D. Hichwa. II. PET studies of memory: novel versus practiced free recall of word lists. NeuroImage 2(4):296-305, 1995. PMID: 9343614. WOBIB: 85.

-5: -0.05400 Other-attribution through cursor movement controlled by a computer versus passive cursor movement. The subject moved a joystick, but a cursor on the screen was controlled by a third "person" (a computer). WOEXP: 73.
Chlöé Farrer; Chris D. Frith. Experiencing oneself vs another person as being the cause of an action: the neural correlates of the experience of agency. NeuroImage 15(3):596-603, 2002. PMID: 11848702. DOI: 10.1006/nimg.2001.1009. WOBIB: 23.

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