WOEXP: 389 - Decreased benzodiazepine receptor binding in panic disorder
 
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Decreased benzodiazepine receptor binding in panic disorder. Decreased benzodiazepine receptor binding in panic disorder in panic disorder patients versus normal control subjects. WOEXP: 389.

J. D. Bremner; R. B. Innis; T. White; M. Fujita; D. Silbersweig; A. W. Goddard; L. Staib; E. Stern; A. Cappiello; S. Woods; R. Baldwin; D. S. Charney. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 47(2):96-106, 2000. PMID: 10664825. WOBIB: 126.

Disease - Panic disorder

Modality:SPECT/MRI
Measured variable: Distribution volume
Tracer: I-123 Iomazenil
Scanner: Digital Scintigraphics CERASPECT
Number of subjects: 29

Asymmetry: 0.93750 (left: -1, right: +1)

  x     y     z   Lobar anatomy Functional area WOROI Value
6 -55 32 Precuneus      
12 -25 -2 Left hippocampus      
16 -31 -5        
26 -43 -11        

corner cube of volume 389 (Decreased benzodiazepine receptor binding in panic disorder)

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Related - positive correlated volumes

+1: 1.00000 Decreased benzodiazepine receptor binding in panic disorder. Decreased benzodiazepine receptor binding in panic disorder in panic disorder patients versus normal control subjects. WOEXP: 389.
J. D. Bremner; R. B. Innis; T. White; M. Fujita; D. Silbersweig; A. W. Goddard; L. Staib; E. Stern; A. Cappiello; S. Woods; R. Baldwin; D. S. Charney. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 47(2):96-106, 2000. PMID: 10664825. WOBIB: 126.

+2: 0.76667 Fearful face recognition with placebo drug versus with ketamine. Fearful face recognition after placebo infusion versus neutral face recognition after placebo infusion and fearful face recognition with ketamine. WOEXP: 479.
Kathryn M. Abel; Matthew P. G. Allin; Katarzyna Kucharska-Pietura; Anthony S. David; Chris Andrew; Steven C. R. Williams; Michael J. Brammer; Mary L. Phillips. Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study. NeuroReport 14(3):387-391, 2003. PMID: 12634489. DOI: 10.1097/01.wnr.0000058031.29600.31. FMRIDCID: . WOBIB: 155.

+3: 0.69199 Item-related memory during semantic retrieval with word for nonliving things versus living. Semantic retrieval with a decision whether a visually presented word was refering to a living or nonliving thing with right hand button response for nonliving things versus living. WOEXP: 572.
Emrah Düzel; Roberto Cabeza; Terence W. Picton; Andrew P. Yonelinas; Henning Scheich; Hans-Jochen Heinze; Endel Tulving. Task-related and item-related brain processes of memory retrieval. Proceedings of the National Academy of Science of the United States of America 96(4):1794-1799, 1999. PMID: 9990104. FMRIDCID: . WOBIB: 181.

+4: 0.56507 Passively viewed scenes. Passive viewing of outdoor scenes, furnished rooms, landscapes and landmarks. WOEXP: 89.
R. Epstein; N. Kanwisher. A cortical representation of the local visual environment. Nature 392(6676):598-601, 1998. PMID: 9560155. DOI: 10.1038/33402. WOBIB: 27.

+5: 0.49492 Buildings visual objects. Visual object stimuli: Building versus faces. WOEXP: 12.
I Levy; U Hasson; G Avidan; T Hendler; R Malach. Center-periphery organization of human object areas. Nature Neuroscience 4(5):533-9, 2001. PMID: 11319563. DOI: 10.1038/87490. WOBIB: 5.

+6: 0.41475 Memory retrieval of voice encoded words versus memory retrieval attempt. Memory retrieval attempt from visually presented words of words earlier presented during a voice task and with right hand button press indication versus memory retrieval attempt on new words. WOEXP: 328.
L. Nyberg; Endel Tulving; R. Habib; L. G. Nilsson; S. Kapur; S. Houle; Roberto Cabeza; A. R. McIntosh. Functional brain maps of retrieval mode and recovery of episodic information. NeuroReport 7(1):249-52, 1995. PMID: 8742463. WOBIB: 105.

+7: 0.40594 Recognition of old spatial configuration versus new configurations. Recognition of old repeated spatial configurations of faces and and pictures of tools from previously shown pairs versus new spatial configurations. WOEXP: 449.
Emrah Düzel; Reza Habib; Michael Rotte; Sebastian Guderian; Endel Tulving; Hans-Jochen Heinze. Human hippocampal and parahippocampal activity during visual associative recognition memory for spatial and nonspatial stimulus configurations. Journal of Neuroscience 23(28):9439-9444, 2003. PMID: 14561873. FMRIDCID: . WOBIB: 146.

+8: 0.39440 Coprolalia during Tourette's syndrome. Vocal tics with coprolia while Tourette patients relaxed with closed eyes. WOEXP: 403.
E. Stern; D. A. Silbersweig; K. Y. Chee; Andrew Holmes; M. M. Robertson; M. Trimble; Christopher D. Frith; Richard S. J. Frackowiak; Raymond J. Dolan. A functional neuroanatomy of tics in Tourette syndrome. Archives of General Psychiatry 57(8):741-748, 2000. PMID: 10920461. FMRIDCID: . WOBIB: 130.

+9: 0.37709 Associative encoding of familiar association versus single item encoding of familiar associations. Generate of a sentence containing three visually displayed words that had been seen before versus repeating the words three times. WOEXP: 437.
Nicola M. Hunkin; Andrew R. Mayes; Lloyd J. Gregory; Amanda K. Nicholas; Julia A. Nunn; Michael J. Brammer; Edward T. Bullmore; Steven C. R. Williams. Novelty-related activation within the medial temporal lobes. Neuropsychologia 40(8):1456-1464, 2002. PMID: 11931949. FMRIDCID: . WOBIB: 143.

+10: 0.37654 Correlation with pain intensity. Correlation with subjective ratings of pain intensity with hot pain right volar forearm. WOEXP: 248.
T. R. Tolle; T. Kaufmann; T. Siessmeier; S. Lautenbacher; A. Berthele; F. Munz; W. Zieglgansberger; F. Willoch; M. Schwaiger; B. Conrad; P. Bartenstein. Region-specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis. Annals of Neurology 45(1):40-47, 1999. PMID: 9894875. WOBIB: 79.

+11: 0.36956 No pain after thalamic stimulation versus chronic facial pain. No pain after thalamic stimulation in the left ventroposterior medial thalamic nucleus (-7, -20, +2) versus chronic pain in the right side of the face. WOEXP: 194.
Ron C. Kupers; J. M. Gybels; Albert Gjedde. Positron emission tomography study of a chronic pain patient successfully treated with somatosensory thalamic stimulation. Pain 87(3):295-302, 2000. PMID: 10963909. WOBIB: 62.

+12: 0.36625 Sadness from films and recall. Sadness generated from viewing silent color feature film involving grieving a friend who committed suicide by hanging and recalling sad autobiographical memories from scripts versus view neutral films and recalling neutral autobiographical memories. WOEXP: 541.
Richard D. Lane; Eric M. Reiman; Geoffrey L. Ahern; Gary E. Schwartz; Richard J. Davidson. Neuroanatomical Correlates of Happiness, Sadness, and Disgust. The American Journal of Psychiatry 154(7):926-933, 1997. PMID: 9210742. FMRIDCID: . WOBIB: 177.

+13: 0.35663 Fearful face recognition with placebo drug. Fearful face recognition after placebo infusion versus neutral face recognition after placebo infusion. WOEXP: 475.
Kathryn M. Abel; Matthew P. G. Allin; Katarzyna Kucharska-Pietura; Anthony S. David; Chris Andrew; Steven C. R. Williams; Michael J. Brammer; Mary L. Phillips. Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study. NeuroReport 14(3):387-391, 2003. PMID: 12634489. DOI: 10.1097/01.wnr.0000058031.29600.31. FMRIDCID: . WOBIB: 155.

+14: 0.34662 Deductive reasoning versus probabilistic. Deductive reasoning based on reading three sentence on a screen, two premises and one conclusion, and determining the truth value. WOEXP: 151.
L. M. Parsons; D. Osherson. New Evidence for Distinct Right and Left Brain Systems for Deductive versus Probabilistic Reasoning. Cerebral Cortex 11(10):954-65, 2001. PMID: 11549618. WOBIB: 47.

+15: 0.33246 Sad versus sad. Recalling of powerful and personal autobiographical emotional episodes invoking sadness versus recalling happy episodes. WOEXP: 485.
Mario Pelletier; Alain Bouthillier; Johanne Levesque; Serge Carrier; Claude Breault; Vincent Paquette; Boualem Mensour; Jean-Maxime Leroux; Gilles Beaudoin; Pierre Bourgouin; Mario Beauregard. Separate neural circuits for primary emotions? Brain activity during self-induced sadness and happiness in professional actors. NeuroReport 14(8):1111-1116, 2003. PMID: 12821792. DOI: 10.1097/01.wnr.0000075421.59944.69. FMRIDCID: . WOBIB: 157.

+16: 0.33094 Disgust from films and recall. Disgust generated from viewing silent color feature film with a scene depicting a rat cravling on a sleeping man and recalling disgust autobiographical memories from scripts versus view neutral films and recalling neutral autobiographical memories. WOEXP: 542.
Richard D. Lane; Eric M. Reiman; Geoffrey L. Ahern; Gary E. Schwartz; Richard J. Davidson. Neuroanatomical Correlates of Happiness, Sadness, and Disgust. The American Journal of Psychiatry 154(7):926-933, 1997. PMID: 9210742. FMRIDCID: . WOBIB: 177.

+17: 0.32696 Obsessive compulsive disorder, positive correlation. Positive correlation with obsessive compulsive disorder symptom intensities while contaminants placed in folded hands. WOEXP: 323.
Philip K. McGuire; C. J. Bench; C. D. Frith; I. M. Marks; Richard S. J. Frackowiak; R. J. Dolan. Functional anatomy of obsessive-compulsive phenomena. British Journal of Psychiatry 164(4):459-468, 1994. PMID: 8038933. WOBIB: 104.

+18: 0.32683 Generation of word-pair associates. Recall of exemplars cued from category labels based on words that were not previously presented versus word repetition. WOEXP: 491.
Tim Shallice; Paul Fletcher; Chris D. Frith; Paul Grasby; Richard S. J. Frackowiak; Raymond J. Dolan. Brain regions associated with acquisition and retrieval of verbal episodic memory. Nature 368(6472):633-635, 1994. PMID: 8145849. DOI: 10.1038/368633a0. FMRIDCID: . WOBIB: 159.

+19: 0.32268 Successful verbal encoding of "list" body words. Verbal encoding of subsequently remembered words from the body of a list of words versus attempted encoding of forgotten words. WOEXP: 434.
B. A. Strange; L. J. Otten; Oliver Josephs; Michael D. Rugg; Raymond J. Dolan. Dissociable human perirhinal, hippocampal, and parahippocampal roles during verbal encoding. Journal of Neuroscience 22(2):523-528, 2002. PMID: 11784798. FMRIDCID: . WOBIB: 142.

+20: 0.31584 Relative metabolic increases in Alzheimer's disease. Relative metabolic differences between Alzheimer's disease patients and controls. WOEXP: 192.
Nora D. Volkow; Wei Zhu; Christoph A. Felder; Klaus Mueller; Tomihisa F. Welsh; Gene J. Wang; Mony J. de Leon. Changes in brain functional homogeneity in subjects with Alzheimer's disease. Psychiatry Research 114(1):39-50, 2002. PMID: 11864808. WOBIB: 61.

+21: 0.31256 Recall of word-pair associates. Recall of exemplars cued from category labels based on previously presented word-pairs associates versus word repetition. WOEXP: 490.
Tim Shallice; Paul Fletcher; Chris D. Frith; Paul Grasby; Richard S. J. Frackowiak; Raymond J. Dolan. Brain regions associated with acquisition and retrieval of verbal episodic memory. Nature 368(6472):633-635, 1994. PMID: 8145849. DOI: 10.1038/368633a0. FMRIDCID: . WOBIB: 159.

+22: 0.31112 Recognition of new spatial configuration versus old configurations. Recognition of new different spatial configurations of faces and and pictures of tools from previously shown pairs versus old spatial configurations. WOEXP: 448.
Emrah Düzel; Reza Habib; Michael Rotte; Sebastian Guderian; Endel Tulving; Hans-Jochen Heinze. Human hippocampal and parahippocampal activity during visual associative recognition memory for spatial and nonspatial stimulus configurations. Journal of Neuroscience 23(28):9439-9444, 2003. PMID: 14561873. FMRIDCID: . WOBIB: 146.

+23: 0.30966 Sadness from recall. Sadness generated from recalling sad autobiographical memories from scripts versus view neutral films and recalling neutral autobiographical memories. WOEXP: 547.
Richard D. Lane; Eric M. Reiman; Geoffrey L. Ahern; Gary E. Schwartz; Richard J. Davidson. Neuroanatomical Correlates of Happiness, Sadness, and Disgust. The American Journal of Psychiatry 154(7):926-933, 1997. PMID: 9210742. FMRIDCID: . WOBIB: 177.

+24: 0.30845 Disgust from films. Disgust generated from viewing silent color feature film with a scene depicting a rat cravling on a sleeping man versus view neutral films and recalling neutral autobiographical memories. WOEXP: 545.
Richard D. Lane; Eric M. Reiman; Geoffrey L. Ahern; Gary E. Schwartz; Richard J. Davidson. Neuroanatomical Correlates of Happiness, Sadness, and Disgust. The American Journal of Psychiatry 154(7):926-933, 1997. PMID: 9210742. FMRIDCID: . WOBIB: 177.

+25: 0.30331 Permanent amnesia, absolute. Hypometabolism in patients with permanent amnesia from either anoxia or Wernicke-Korsakoff's syndrome versus normal control subjects. WOEXP: 369.
A. M. Aupee; B. Desgranges; F. Eustache; C. Lalevee; V. de la Sayette; F. Viader; J. C. Baron. Voxel-based mapping of brain hypometabolism in permanent amnesia with PET. NeuroImage 13(6 Pt 1):1164-73, 2001. PMID: 11352622. DOI: 10.1006/nimg.2001.0762. WOBIB: 119.


Antirelated - negatively correlated volumes

-1: -0.05971 Semantic versus pseudoword syllable counting via case judgment. Decision whether a visually presented word is abstract or concrete with right hand response button press versus syllable counting of peudowords with case judgment as double subtracted. WOEXP: 560.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

-2: -0.05358 Semantic versus case. Decision whether a visually presented word is abstract or concrete with right hand response button press versus decision based on the case of the letters in the word. WOEXP: 550.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

-3: -0.04839 Syllable counting versus semantic judgment. Syllable counting of visually presented words and button press with right hand versus decision whether a visually presented word is abstract or concrete. WOEXP: 555.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

-4: -0.04828 Spatial intelligence. Mismatch in a high-g intelligence task determining the odd one of four displayed drawings with indication by button press with middle and index fingers of the two hands versus a similar task with lower g. WOEXP: 339.
John Duncan; Rüdiger J. Seitz; J. Kolodny; D. Bor; H. Herzog; A. Ahmed; F. N. Newell; H. Emslie. A neural basis for general intelligence. Science 289(5478):457-60, 2000. PMID: 10903207. WOBIB: 110.

-5: -0.04669 Semantic versus syllable counting via case judgment. Decision whether a visually presented word is abstract or concrete with right hand response button press versus syllable counting with case judgment as double subtracted. WOEXP: 558.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

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