WOEXP: 387 - Decrease in obsessive-compulsive disorder patients after treatment with paroxetine
 
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Decrease in obsessive-compulsive disorder patients after treatment with paroxetine. Decrease in obsessive-compulsive disorder patients after treatment with paroxetine. WOEXP: 387.

Elsebet S. Hansen; Steen Hasselbalch; Ian Law; Tom G. Bolwig. The caudate nucleus in obsessive-compulsive disorder. Reduced metabolism following treatment with paroxetine: a PET study. International Journal of Neuropsychopharmacology 5(1):1-10, 2002. PMID: 12057027. DOI: doi:10.1017/S1461145701002681. WOBIB: 125.

Drug - Paroxetine
Disease - Obsessive compulsive disorder
WOEXT: 378.

Modality:PET
Measured variable: CMRGlu
Tracer: F-18 2-deoxy-2-fluro-D-glucose (FDG)
Scanner: GE Medical Systems, Advance NXi
Number of subjects: 20

Asymmetry: 0.27344 (left: -1, right: +1)

  x     y     z   Lobar anatomy Functional area WOROI Value
10 12 -2 Right caudate nucleus     1.59
-46 16 1 Left inferior frontal cortex     1.22
48 -6 0 Right insula     0.83
12 -67 11 Right inferior cuneus     1.30
-18 -89 -22 Left cerebellum     1.22
24 38 24 Right dorsolateral prefrontal cortex     0.93
-8 39 7 Left anterior cingulate cortex     1.22

corner cube of volume 387 (Decrease in obsessive-compulsive disorder patients after treatment with paroxetine)

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Related - positive correlated volumes

+1: 1.00000 Decrease in obsessive-compulsive disorder patients after treatment with paroxetine. Decrease in obsessive-compulsive disorder patients after treatment with paroxetine. WOEXP: 387.
Elsebet S. Hansen; Steen Hasselbalch; Ian Law; Tom G. Bolwig. The caudate nucleus in obsessive-compulsive disorder. Reduced metabolism following treatment with paroxetine: a PET study. International Journal of Neuropsychopharmacology 5(1):1-10, 2002. PMID: 12057027. DOI: doi:10.1017/S1461145701002681. WOBIB: 125.

+2: 0.97863 Obsessive-compulsive disorder severity. Correlation with obsessive-compulsive disorder severity in patients before and after treatment with paroxetine. WOEXP: 388.
Elsebet S. Hansen; Steen Hasselbalch; Ian Law; Tom G. Bolwig. The caudate nucleus in obsessive-compulsive disorder. Reduced metabolism following treatment with paroxetine: a PET study. International Journal of Neuropsychopharmacology 5(1):1-10, 2002. PMID: 12057027. DOI: doi:10.1017/S1461145701002681. WOBIB: 125.

+3: 0.40932 Increase due to hypnosis versus rest and mental imagery. Increases due to hypnosis versus rest and mental imagery. During warmth and hot pain the thenar surface of the right hand. WOEXP: 239.
M. E. Faymonville; S. Laureys; C. Degueldre; G. DelFiore; A. Luxen; G. Franck; M. Lamy; P. Maquet. Neural mechanisms of antinociceptive effects of hypnosis. Anesthesiology 92(5):1257-67, 2000. PMID: 10781270. WOBIB: 76.

+4: 0.39161 Rhyme judgement and nonlinear ('convex') response in rapid auditory processing. Conjunction between rhyme judgment of visually presented words pairs and nonlinear (reverse U-shaped) response as a function of compression/presentation speed of auditorily presented sentences that were to be determine semantically true with button press. WOEXP: 526.
Russell A. Poldrack; Elise Temple; Athanassios Protopapas; Srikantan Nagarajan; Paula Tallal; Michael Merzenich; John D. E. Gabrieli. Relations Between the Neural Bases of Dynamic Auditory Processing and Phonological Processing: Evidence from fMRI. Journal of Cognitive Neuroscience 13(5):687-697, 2001. PMID: 11506664. FMRIDCID: 2-2001-111KR. WOBIB: 171.

+5: 0.38703 Correlation with speed during navigation and movement. Correlation with speed of virtual movement in navigation and movement in a virtual town. WOEXP: 131.
Eleanor A. Maguire; N. Burgess; J. G. Donnett; Richard S. J. Frackowiak; C. D. Frith; J. O'Keefe. Knowing where and getting there: a human navigation network. Science 280(5365):921-4, 1998. PMID: 9572740. WOBIB: 38.

+6: 0.37998 Heat pain on left hand. Heat pain on dorsal surface of the left hand with and without a Stroop task versus warm. WOEXP: 312.
Brent A. Vogt; Stuart Derbyshire; Anthony K. Jones. Pain processing in four regions of human cingulate cortex localized with co-registered PET and MR imaging. European Journal of Neuroscience 8(7):1461-73, 1996. PMID: 8758953. WOBIB: 100.

+7: 0.37771 75% disgusted faces versus neural faces. Viewing of 75% computer-manipulated grey-scale faces with an expression of disgust and with sex decision task indicated with right thumb versus viewing of slightly happy faces. WOEXP: 222.
Mary L. Phillips; A. W. Young; C. Senior; M. Brammer; C. Andrew; A. J. Calder; E. T. Bullmore; D. I. Perrett; D. Rowland; Steven C. R. Williams; J. A. Gray; Anthony S. David. A specific neural substrate for perceiving facial expressions of disgust. Nature 389(6650):495-8, 1997. PMID: 9333238. DOI: 10.1038/39051. WOBIB: 71.

+8: 0.37527 Time-context-specific recall. Time-context-specific cued recall of words from auditorily presented syllables versus word completion from syllable. WOEXP: 109.
Toshikatsu Fujii; Jiro Okuda; Takashi Tsukiura; Hiroya Ohtake; Rina Miura; Reiko Fukatsu; Kyoko Suzuki; Ryuta Kawashima; Masatoshi Itoh; Hiroshi Fukuda; Atsushi Yamadori. The role of the basal forebrain in episodic memory retrieval: a positron emission tomography study. NeuroImage 15(3):501-8, 2002. PMID: 11848693. DOI: 10.1006/nimg.2001.0995. WOBIB: 32.

+9: 0.37424 Rhyme judgement and linear increase response in rapid auditory processing. Conjunction between rhyme judgment of visually presented words pairs and linear increase response as a function of compression/presentation speed of auditorily presented sentences that were to be determine semantically true with button press. WOEXP: 527.
Russell A. Poldrack; Elise Temple; Athanassios Protopapas; Srikantan Nagarajan; Paula Tallal; Michael Merzenich; John D. E. Gabrieli. Relations Between the Neural Bases of Dynamic Auditory Processing and Phonological Processing: Evidence from fMRI. Journal of Cognitive Neuroscience 13(5):687-697, 2001. PMID: 11506664. FMRIDCID: 2-2001-111KR. WOBIB: 171.

+10: 0.36561 Attended heat pain on left hand. 46 to 49 degrees Celsius hot stimuli on the thenar eminence of the left hand using a peltier thermode versus 40 degrees warm stimuli. WOEXP: 188.
Jonathan C. W. Brooks; Turo J. Nurmikko; William E. Bimson; Krish D. Singh; Neil Roberts. fMRI of thermal pain: effects of stimulus laterality and attention. NeuroImage 15(2):293-301, 2002. PMID: 11798266. DOI: 10.1006/nimg.2001.0974. WOBIB: 60.

+11: 0.36188 150% disgusted faces versus neural faces. Viewing of 150% computer-manipulated grey-scale faces with an expression of disgust and with sex decision task indicated with right thumb versus viewing of slightly happy faces. WOEXP: 223.
Mary L. Phillips; A. W. Young; C. Senior; M. Brammer; C. Andrew; A. J. Calder; E. T. Bullmore; D. I. Perrett; D. Rowland; Steven C. R. Williams; J. A. Gray; Anthony S. David. A specific neural substrate for perceiving facial expressions of disgust. Nature 389(6650):495-8, 1997. PMID: 9333238. DOI: 10.1038/39051. WOBIB: 71.

+12: 0.35748 Evaluative judgment versus episodic memory retrieval. Evaluative judgment from visually sentences with a yes/no response using right fingers versus episodic memory retrieval. WOEXP: 378.
Stefan Zysset; Oswald Huber; Evelyn Ferstl; D. Y. von Cramon. The anterior frontomedian cortex and evaluative judgment: an fMRI study. NeuroImage 15(4):983-91, 2002. PMID: 11906238. DOI: 10.1006/nimg.2001.1008. WOBIB: 121.

+13: 0.35615 Verbal fluency. Naming words beginning with a given letter while focusing on a cross on a screen versus reading color words. WOEXP: 539.
Barbara Ravnkilde; Poul Videbech; Raben Rosenberg; Albert Gjedde; Anders Gade. Putative Tests of Frontal Lobe Function: A PET-Study of Brain Activation During Stroop's Test and Verbal Fluency. Journal of Clinical and Experimental Neuropsychology 24(4):534-547, 2002. PMID: 12187466. DOI: 10.1076/jcen.24.4.534.1033. FMRIDCID: . WOBIB: 176.

+14: 0.35054 Immediate reward. Choice with immediate reward available with selections visual presented and choices made by pressing one of two buttons versus with no immediate reward available. WOEXP: 579.
Samuel M. McClure; David I. Laibson; George Loewenstein; Jonathan D. Cohen. Separate Neural Systems Value Immediate and Delayed Monetary Rewards. Science 306(5695):503-507, 2004. PMID: 15486304. DOI: 10.1126/science.1100907. FMRIDCID: . WOBIB: 184.

+15: 0.34837 Semantic versus syllable counting via case judgment. Decision whether a visually presented word is abstract or concrete with right hand response button press versus syllable counting with case judgment as double subtracted. WOEXP: 558.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

+16: 0.33385 Practiced word recall versus novel word recall. Speak load words recalled from a list of 15 words practiced one week before versus speak words aloud from a list of words heard just prior to recall. WOEXP: 276.
Nancy C. Andreasen; D. S. O'Leary; T. Cizadlo; Stephan Arndt; K. Rezai; G. L. Watkins; L. L. Ponto; R. D. Hichwa. II. PET studies of memory: novel versus practiced free recall of word lists. NeuroImage 2(4):296-305, 1995. PMID: 9343614. WOBIB: 85.

+17: 0.32989 Reflective self-awareness on physical appearance. Reflection on one's own physical appearance versus reflection on the physical appearance of a famous third person. WOEXP: 105.
Troels Kjaer; Markus Nowak; Hans Lou. Reflective Self-Awareness and Conscious States: PET Evidence for a Common Midline Parietofrontal Core. NeuroImage 17(2):1080, 2002. PMID: 12377180. WOBIB: 31.

+18: 0.32219 Romantic love. Viewing of colored pictures of the faces of boy- or girlfriend (loved once) versus viewing of colored pictures of three friends of the same sex as their loved partner. WOEXP: 176.
Andreas Bartels; Semir Zeki. The neural basis of romantic love. NeuroReport 11(17):3829-3834, 2000. PMID: 11117499. WOBIB: 54.

+19: 0.32153 Happy face viewing. Viewing happy emotional face and indication with a button press versus viewing neutral faces. WOEXP: 307.
Mary L. Phillips; E. T. Bullmore; R. Howard; P. W. Woodruff; I. C. Wright; Steven C. R. Williams; A. Simmons; C. Andrew; M. Brammer; Anthony S. David. Investigation of facial recognition memory and happy and sad facial expression perception: an fMRI study. Psychiatry Research 83(3):127-38, 1998. PMID: 9849722. WOBIB: 98.

+20: 0.32071 Nonconscious retrieval of face-word associations. Nonconscious retrieval of brief visual presented face-word pairs where the words indicated occupation during the guessing of the occupation category from faces versus guessing of occupation category from nonconscious viewed faces not associated with occupations. WOEXP: 469.
Katharina Henke; Christian R. A. Mondadori; Valerie Treyer; Roger M. Nitsch; Alfred Buck; Christoph Hock. Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia 41(8):863-876, 2003. PMID: 12667523. FMRIDCID: . WOBIB: 152.

+21: 0.31588 Mildly depressed cancer patients. Cancer patients that might be mildly depressed versus patients with chronic hepatitis. WOEXP: 293.
M. Tashiro; F. D. Juengling; M. J. Reinhardt; I. Brink; S. Hoegerle; M. Mix; K. Kubota; K. Yamaguchi; M. Itoh; H. Sasaki; E. Moser; E. U. Nitzsche. Reproducibility of PET brain mapping of cancer patients. Psychooncology 9(2):157-63, 2000. PMID: 10767753. WOBIB: 92.

+22: 0.31259 Autobiographical episodic memory retrieval. Listening to sentences that contained first person autobiographical episodic infomation versus resting eyes closed. WOEXP: 208.
G. R. Fink; H. J. Markowitsch; M. Reinkemeier; T. Bruckbauer; J. Kessler; W. D. Heiss. Cerebral representation of one's own past: neural networks involved in autobiographical memory. Journal of Neuroscience 16(13):4275-82, 1996. PMID: 8753888. WOBIB: 68.

+23: 0.30940 Cold pain on right foot masked by silent word reading. 0-2 centigrades cold pain on dorsal surface of the right foot with an and mask from silent word reading versus rest with attention to the sound of the machine. WOEXP: 264.
U. N. Frankenstein; W. Richter; M. C. McIntyre; F. Remy. Distraction modulates anterior cingulate gyrus activations during the cold pressor test. NeuroImage 14(4):827-36, 2001. PMID: 11554801. DOI: 10.1006/nimg.2001.0883. WOBIB: 83.

+24: 0.30779 Memory retrieval of meaning encoded words versus silent reading. Memory retrieval from visually presented words of words earlier encoded during a meaning task and with right hand button press indication versus silent reading of visually presented words. WOEXP: 325.
L. Nyberg; Endel Tulving; R. Habib; L. G. Nilsson; S. Kapur; S. Houle; Roberto Cabeza; A. R. McIntosh. Functional brain maps of retrieval mode and recovery of episodic information. NeuroReport 7(1):249-52, 1995. PMID: 8742463. WOBIB: 105.

+25: 0.30656 Painful stimulation of the left hand. Painful stimulation of the left hand by laser. WOEXP: 34.
X. Xu; H. Fukuyama; S. Yazawa; T. Mima; T. Hanakawa; Y. Magata; M. Kanda; N. Fujiwara; K. Shindo; T. Nagamine; H. Shibasaki. Functional localization of pain perception in the human brain studied by PET. NeuroReport 8(2):555-559, 1997. PMID: 9080447. WOBIB: 13.


Antirelated - negatively correlated volumes

-1: -0.07479 Visual pursuit tracking. Visual pursuit tracking eye movement by following a white spot on a screen moving sinusoidal along the horizontal meridian versus central fixation. WOEXP: 149.
R. A. Berman; C. L. Colby; C. R. Genovese; J. T. Voyvodic; B. Luna; K. R. Thulborn; J. A. Sweeney. Cortical networks subserving pursuit and saccadic eye movements in humans: an FMRI study. Human Brain Mapping 8(4):209-25, 1999. PMID: 10619415. WOBIB: 46.

-2: -0.07216 Visually guided saccades. Visually guided saccadic eye movements by following an white spot on a screen unpredictably right and left jumping along the horizontal meridian versus central fixation. WOEXP: 150.
R. A. Berman; C. L. Colby; C. R. Genovese; J. T. Voyvodic; B. Luna; K. R. Thulborn; J. A. Sweeney. Cortical networks subserving pursuit and saccadic eye movements in humans: an FMRI study. Human Brain Mapping 8(4):209-25, 1999. PMID: 10619415. WOBIB: 46.

-3: -0.07101 Covariation to precuneus during self-reflection. . WOEXP: 107.
Troels Kjaer; Markus Nowak; Hans Lou. Reflective Self-Awareness and Conscious States: PET Evidence for a Common Midline Parietofrontal Core. NeuroImage 17(2):1080, 2002. PMID: 12377180. WOBIB: 31.

-4: -0.06123 Rest versus practiced word recall. Resting versus speak load words recalled from a list of 15 words practiced one week before. WOEXP: 272.
Nancy C. Andreasen; D. S. O'Leary; T. Cizadlo; Stephan Arndt; K. Rezai; G. L. Watkins; L. L. Ponto; R. D. Hichwa. II. PET studies of memory: novel versus practiced free recall of word lists. NeuroImage 2(4):296-305, 1995. PMID: 9343614. WOBIB: 85.

-5: -0.05841 Navigation and movement in a virtual town. Navigation and movement in a virtual town versus static scenes. WOEXP: 130.
Eleanor A. Maguire; N. Burgess; J. G. Donnett; Richard S. J. Frackowiak; C. D. Frith; J. O'Keefe. Knowing where and getting there: a human navigation network. Science 280(5365):921-4, 1998. PMID: 9572740. WOBIB: 38.

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