WOEXP: 299 - Late phase heat pain
 
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Late phase heat pain. 50 degrees Celsius heat on the left volar forearm starting 40 seconds prior to the scanning onset versus 40 degrees warm stimulus. WOEXP: 299.

K. L. Casey; T. J. Morrow; J. Lorenz; S. Minoshima. Temporal and spatial dynamics of human forebrain activity during heat pain: analysis by positron emission tomography. Journal of Neurophysiology 85(2):951-9, 2001. PMID: 11160525. WOBIB: 95.

Perception,Somesthesis - Temperature
Perception,Somesthesis - Pain
Cognition,Attention - Late phase heat pain
WOEXT: 306.

Modality:PET
Measured variable: CBF
Tracer: O-15 Water
Scanner: Siemens, 931/08-12
Number of subjects: 14

Asymmetry: -0.39276 (left: -1, right: +1)

  x     y     z   Lobar anatomy Functional area WOROI Value
-39 1 11 Mid-insular      
-31 -14 8 N. lenticularis/posterior insula      
-24 -17 58   M1/S1    
-6 -1 38 Cingulate cortex (mid-anterior)      
-37 -19 20   S2 cortex    
-3 -56 -14 Cerebellar vermis      
-51 -4 38   Premotor    
-15 -24 9 Thalamus, ventral posterior      
21 -15 9 Thalamus, ventral lateral/n. lenticularis      
8 -19 9 Medial thalamus      
21 -60 -20 Cerebellum, paravermal      
35 3 4 Mid-insula      
48 -19 25   S2 cortex    
10 3 29 Cingulate cortex, mid-anterior      

corner cube of volume 299 (Late phase heat pain)

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Related - positive correlated volumes

+1: 1.00000 Late phase heat pain. 50 degrees Celsius heat on the left volar forearm starting 40 seconds prior to the scanning onset versus 40 degrees warm stimulus. WOEXP: 299.
K. L. Casey; T. J. Morrow; J. Lorenz; S. Minoshima. Temporal and spatial dynamics of human forebrain activity during heat pain: analysis by positron emission tomography. Journal of Neurophysiology 85(2):951-9, 2001. PMID: 11160525. WOBIB: 95.

+2: 0.74547 Heat pain - female. 50 degrees heat pain on the left forearm of females versus 40 degrees stimulus. WOEXP: 368.
P. E. Paulson; S. Minoshima; T. J. Morrow; K. L. Casey. Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans. Pain 76(1-2):223-9, 1998. PMID: 9696477. WOBIB: 118.

+3: 0.73180 Heat pain - male. 50 degrees heat pain on the left forearm of males versus 40 degrees stimulus. WOEXP: 367.
P. E. Paulson; S. Minoshima; T. J. Morrow; K. L. Casey. Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans. Pain 76(1-2):223-9, 1998. PMID: 9696477. WOBIB: 118.

+4: 0.70041 Heat pain on left arm. 50 degrees heat pain stimuli on six separate sites on the left volar forearm versus 40 degrees stimuli. WOEXP: 319.
K. L. Casey; S. Minoshima; T. J. Morrow; R. A. Koeppe. Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain. Journal of Neurophysiology 76(1):571-81, 1996. PMID: 8836245. WOBIB: 102.

+5: 0.69567 Active right middle finger movement versus passive movement. Active repetitive flexion-extension movement of the right middle finger at the metacarpophalangeal joint auditory-cued by a beep versus passive movement with beeps. WOEXP: 270.
T. Mima; A. Ikeda; S. Yazawa; T. Kunieda; T. Nagamine; W. Taki; H. Shibasaki. Somesthetic function of supplementary motor area during voluntary movements. NeuroReport 10(9):1859-62, 1999. PMID: 10501521. WOBIB: 84.

+6: 0.65911 Cold pain on left arm. 6 degrees heat pain stimuli by immersion of the left hand in water to the wrist versus 20 degrees stimuli. WOEXP: 320.
K. L. Casey; S. Minoshima; T. J. Morrow; R. A. Koeppe. Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain. Journal of Neurophysiology 76(1):571-81, 1996. PMID: 8836245. WOBIB: 102.

+7: 0.59534 Active elbow movement versus passive movement. Active flexion and extension movements of the elbow of the right arm paced by a metronome versus passive movement. WOEXP: 464.
C. Weiller; M. Juptner; S. Fellows; M. Rijntjes; G. Leonhardt; S. Kiebel; S. Muller; H. C. Diener; A. F. Thilmann. Brain representation of active and passive movements. NeuroImage 4(2):105-110, 1996. PMID: 9345502. FMRIDCID: . WOBIB: 151.

+8: 0.55475 Cold pain in left hand. Left hand immersed in cold circulating water with a temperature of 0-0.5 degrees Celsius while either fixating or engaged in a externally driven perceptual maze task versus immersion in 19 degrees Celsius water and fixating or performing the maze task. WOEXP: 184.
P. Petrovic; K. M. Petersson; P. H. Ghatan; S. Stone-Elander; M. Ingvar. Pain-related cerebral activation is altered by a distracting cognitive task. Pain 85(1-2):19-30, 2000. PMID: 10692599. WOBIB: 58.

+9: 0.53528 Nitroglycerin-provoked cluster headache. Nitroglycerin-provoked acute headache in cluster headache patients versus pain-free state. WOEXP: 424.
Arne May; Anish Bahra; Christian Büchel; Richard S. J. Frackowiak; Peter J. Goadsby. Hypothalamic activation in cluster headache attacks. Lancet 352(9124):275-278, 1998. PMID: 9690407. FMRIDCID: . WOBIB: 137.

+10: 0.52540 Micturition. Micturition after the bladder had been filled to the normal desire to void. WOEXP: 50.
S. Nour; Claus Svarer; J. K. Kristensen; O. B. Paulson; I. Law. Cerebral activation during micturition in normal men. Brain 123 ( Pt 4):781-9, 2000. PMID: 10734009. WOBIB: 17.

+11: 0.50973 Cursor movement with joystick. Movement of a cursor controlled with right hand through a joystick from the center of the screen to one of eight positions arranged radially and further to a new position at the same angle but further away from the center. WOEXP: 148.
J. M. Ellermann; J. D. Siegal; J. P. Strupp; T. J. Ebner; K. Ugurbil. Activation of visuomotor systems during visually guided movements: a functional MRI study. Journal of Magnetic Resonance 131(2):272-285, 1998. PMID: 9571103. WOBIB: 45.

+12: 0.50591 Right index finger tapping. Right index finger tapping with eight different frequencies cused by a 500Hz sound versus no finger tapping. WOEXP: 510.
Morten Blinkenberg; Christian Bonde; Sĝren Holm; Claus Svarer; Jimmy Andersen; Olaf B. Paulson; Ian Law. Rate dependence of regional cerebral activation during performance of a repetitive motor task: a PET study. Journal of Cerebral Blood Flow and Metabolism 16(5):794-803, 1996. PMID: 8784224. DOI: 10.1097/00004647-199609000-00004. FMRIDCID: . WOBIB: 166.

+13: 0.49907 Cold pain in right hand. 5 degrees cold pain on the palmar surface of the right hand versus normal 34 degrees. WOEXP: 213.
A. D. Craig; Eric M. Reiman; A. Evans; M. C. Bushnell. Functional imaging of an illusion of pain. Nature 384(6606):258-60, 1996. PMID: 8918874. WOBIB: 69.

+14: 0.49907 Grill illusion in right hand. Thermal grill with spatially alternating 20 degrees cold and 40 degrees warm pain stimuli on the palmar surface of the right hand versus normal 34 degrees. WOEXP: 215.
A. D. Craig; Eric M. Reiman; A. Evans; M. C. Bushnell. Functional imaging of an illusion of pain. Nature 384(6606):258-60, 1996. PMID: 8918874. WOBIB: 69.

+15: 0.49907 Hot pain in right hand. 47 degrees hot pain on the palmar surface of the right hand versus normal 34 degrees. WOEXP: 217.
A. D. Craig; Eric M. Reiman; A. Evans; M. C. Bushnell. Functional imaging of an illusion of pain. Nature 384(6606):258-60, 1996. PMID: 8918874. WOBIB: 69.

+16: 0.49669 Auditory oddball. Frequent 1000Hz tones interrupted by infrequent oddball 1500Hz tones which should result in button press. WOEXP: 53.
Silvina Horovitz; Pawel Skudlarski; John Gore. Correlations and dissociations between BOLD signal and P300 amplitude in an auditory oddball task: a parametric approach to combining fMRI and ERP. Magnetic Resonance Imaging 20(4):319, 2002. PMID: 12165350. WOBIB: 19.

+17: 0.48503 Heat pain on right arm. Hot pain 1 degree over pain threshold on right volar forearm versus warm stimuli 1 degree below pain threshold. WOEXP: 245.
T. R. Tolle; T. Kaufmann; T. Siessmeier; S. Lautenbacher; A. Berthele; F. Munz; W. Zieglgansberger; F. Willoch; M. Schwaiger; B. Conrad; P. Bartenstein. Region-specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis. Annals of Neurology 45(1):40-47, 1999. PMID: 9894875. WOBIB: 79.

+18: 0.48006 Self-generated saccades. Voluntary self-generated large-amplitude horizontal saccades with eyes open versus resting state with eyes closed. WOEXP: 1.
Ian Law; Claus Svarer; Egill Rostrup; Olaf B. Paulson. Parieto-occipital cortex activation during self-generated eye movements in the dark. Brain 121 ( Pt 11):2189-200, 1998. PMID: 9827777. WOBIB: 1.

+19: 0.47505 Pointing to previous target versus fixation. Movement of a stylus with the right hand for the movement of a screen cursor from a central fixation point to a target in the periphery shown in the previous round versus passive fixation. WOEXP: 574.
F. Lacquaniti; Daniela Perani; E. Guigon; V. Bettinardi; M. Carrozzo; F. Grassi; Yves Rossetti; F. Fazio. Visuomotor Transformations for Reaching to Memorized Targets: A PET study. NeuroImage 5(2):129-146, 1997. PMID: 9345543. DOI: 10.1006.nimg.1996.0254. FMRIDCID: . WOBIB: 182.

+20: 0.47352 Distracted heat pain on right hand. 46 to 49 degrees Celsius hot stimuli on the thenar eminence of the right hand using a peltier thermode distracted by a visual motion task with silent counting of the number of partial coherent visual motion blocks versus distract 40 degrees warm stimuli. WOEXP: 187.
Jonathan C. W. Brooks; Turo J. Nurmikko; William E. Bimson; Krish D. Singh; Neil Roberts. fMRI of thermal pain: effects of stimulus laterality and attention. NeuroImage 15(2):293-301, 2002. PMID: 11798266. DOI: 10.1006/nimg.2001.0974. WOBIB: 60.

+21: 0.47258 Active right middle finger movement versus rest. Repetitive flexion-extension movement of the right middle finger at the metacarpophalangeal joint auditory-cued by a beep versus rest with listening to beeps. WOEXP: 268.
T. Mima; A. Ikeda; S. Yazawa; T. Kunieda; T. Nagamine; W. Taki; H. Shibasaki. Somesthetic function of supplementary motor area during voluntary movements. NeuroReport 10(9):1859-62, 1999. PMID: 10501521. WOBIB: 84.

+22: 0.47236 Practiced word recall versus rest. Speak load words recalled from a list of 15 words practiced one week before versus rest. WOEXP: 271.
Nancy C. Andreasen; D. S. O'Leary; T. Cizadlo; Stephan Arndt; K. Rezai; G. L. Watkins; L. L. Ponto; R. D. Hichwa. II. PET studies of memory: novel versus practiced free recall of word lists. NeuroImage 2(4):296-305, 1995. PMID: 9343614. WOBIB: 85.

+23: 0.47030 Heat pain on left hand. Heat pain on dorsal surface of the left hand with and without a Stroop task versus warm. WOEXP: 312.
Brent A. Vogt; Stuart Derbyshire; Anthony K. Jones. Pain processing in four regions of human cingulate cortex localized with co-registered PET and MR imaging. European Journal of Neuroscience 8(7):1461-73, 1996. PMID: 8758953. WOBIB: 100.

+24: 0.46530 Positive interaction between predictable tones and button press. Positive interaction between predictable tones and self-paced button presses versus no button presses and random tones with button press. WOEXP: 260.
S. J. Blakemore; Geraint Rees; C. D. Frith. How do we predict the consequences of our actions? A functional imaging study. Neuropsychologia 36(6):521-9, 1998. PMID: 9705062. WOBIB: 82.

+25: 0.45876 Cold pain versus cold pain with silent word reading. 0-2 centigrades cold pain on dorsal surface of the right foot versus cold pain distracted by silent word. WOEXP: 266.
U. N. Frankenstein; W. Richter; M. C. McIntyre; F. Remy. Distraction modulates anterior cingulate gyrus activations during the cold pressor test. NeuroImage 14(4):827-36, 2001. PMID: 11554801. DOI: 10.1006/nimg.2001.0883. WOBIB: 83.


Antirelated - negatively correlated volumes

-1: -0.07486 Decreased activity during REM sleep. Slow-wave sleep or wakefull-state versus REM sleep. WOEXP: 301.
P. Maquet; J. Peters; J. Aerts; G. Delfiore; C. Degueldre; A. Luxen; G. Franck. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming. Nature 383(6596):163-6, 1996. PMID: 8774879. WOBIB: 96.

-2: -0.06796 Passive versus active, hypothesis generation and testing group with replication. Passive state with simulus versus active states in connection with visual information processing task: same-different discrimination, visual search, spatial attention, language, memory, cross-modal imagery. hypothesis generation and testing group. WOEXP: 531.
Gordon L. Shulman; Julie A. Fiez; Maurizio Corbetta; Randy L. Buckner; Francis M. Miezin; Marcus E. Raichle; Steven E. Petersen. Common Blood Flow Changes across Visual Tasks: II. Decreases in Cerebral Cortex. Journal of Cognitive Neuroscience 9(5):648-663, 1997. FMRIDCID: . WOBIB: 173.

-3: -0.06712 Empathic judgements. Judgements of visually displayed sentences about empathic situations with button press versus judgement involving social reasoning. WOEXP: 450.
T. F. Farrow; Y. Zheng; I. D. Wilkinson; S. A. Spence; J. F. Deakin; N. Tarrier; P. D. Griffiths; P. W. Woodruff. Investigating the functional anatomy of empathy and forgiveness. NeuroReport 12(11):2433-2438, 2001. PMID: 11496124. FMRIDCID: . WOBIB: 147.

-4: -0.06700 Object decision. Decision whether a picture represented an object or a non-object. WOEXP: 2.
Christian Gerlach; I. Law; Anders Gade; O. B. Paulson. Categorization and category effects in normal object recognition: a PET study. Neuropsychologia 38(13):1693-703, 2000. PMID: 11099727. WOBIB: 2.

-5: -0.06278 Decreases in self-paced button press while listening to tones. Decreases in self-paced button presses with the thumb of the right hand versus no movement. Both condition when listening to tones. WOEXP: 257.
S. J. Blakemore; Geraint Rees; C. D. Frith. How do we predict the consequences of our actions? A functional imaging study. Neuropsychologia 36(6):521-9, 1998. PMID: 9705062. WOBIB: 82.

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