WOEXP: 292 - Decline in Alzheimer's disease
 
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Decline in Alzheimer's disease. Patients with Alzheimer's disease in 1-year follow-up during mental resting state versus early Alzheimer's disease. WOEXP: 292.

Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. American Journal of Psychiatry 159(5):738-45, 2002. PMID: 11986126. WOBIB: 91.

Disease - Alzheimer's disease
WOEXT: 219.

Modality:PET
Measured variable: CMRGlu
Tracer: F-18 2-deoxy-2-fluro-D-glucose (FDG)
Scanner: Scanditronix, PC4096-7B
Number of subjects: 14

Asymmetry: 0.78467 (left: -1, right: +1)

  x     y     z   Lobar anatomy Functional area WOROI Value
-22 54 27 Left superior frontal      
-48 8 36 Left midfrontal      
-44 38 24 Left midfrontal      
32 37 35 Right midfrontal      
28 40 27 Right midfrontal      
53 34 17 Right midfrontal      
42 43 9 Right midfrontal - inferior frontal      
-48 27 -5 Left inferior frontal      
51 15 25 Right inferior frontal      
48 17 -4 Right inferior frontal      
-53 3 22   Left premotor    
51 -48 21 Right superior temporal      
-67 -14 -9 Left midtemporal      
63 -47 2 Right midtemporal      
63 -51 -1 Right midtemporal - inferior temporal      
53 -36 -12 Right inferior temporal      
57 -61 -7 Right fusiform      
34 -14 -13 Right hippocampal      
-63 -39 35 Left inferior parietal      
55 -56 43 right inferior parietal      
-57 -53 32 Left supramarginal      
-2 30 21 Anterior cingulate      
-2 37 -2 Anterior cingulate      
-2 -39 28 Posterior cingulate      
4 -39 42 Right precuneus      
-36 -23 38 Left precentral-postcentral      
38 -10 37 Right precentral-postcentral      
32 -82 23 Right midoccipital      
26 -7 8 Right lentiform nucleus      
6 -11 4 Right thalamus      
6 -12 -9 Right midbrain      

corner cube of volume 292 (Decline in Alzheimer's
      disease)

[ PNG | VRML (179Kb) ]

Related - positive correlated volumes

+1: 1.00000 Decline in Alzheimer's disease. Patients with Alzheimer's disease in 1-year follow-up during mental resting state versus early Alzheimer's disease. WOEXP: 292.
Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. American Journal of Psychiatry 159(5):738-45, 2002. PMID: 11986126. WOBIB: 91.

+2: 0.49868 Feign autobiographical memory impairment. Feigning memory impairment in autobiographical memory versus accurate recall. WOEXP: 125.
Tatia M. C. Lee; Ho-Ling Liu; Li-Hai Tan; Chetwyn C. H. Chan; Srikanth Mahankali; Ching-Mei Feng; Jinwen Hou; Peter T. Fox; Jia-Hong Gao. Lie detection by functional magnetic resonance imaging. Human Brain Mapping 15(3):157-64, 2002. PMID: 11835606. WOBIB: 37.

+3: 0.40662 Female phonological processing. Detemination by women whether two visually presented nonsense words rhymed or not with response by pressing a bulb versus letter case judgement. WOEXP: 517.
Bennett A. Shaywitz; Sally E. Shaywitz; Kenneth R. Pugh; R. Todd Constable; Pawl Skudlawski; Robert K. Fulbright; Richard A. Bronen; Jack M. Fletcher; Donald P. Shankwiler; Leonard Katz; John C. Gore. Sex differences in the functional organization of the brain for language. Nature 373(6515):607-609, 1995. PMID: 7854416. DOI: 10.1038/373607a0. FMRIDCID: . WOBIB: 169.

+4: 0.38054 Hot pain on left hand (group 1). 46 degrees hot pain to the dorsum of the left hand versus 35 degree stimuli. WOEXP: 225.
L. R. Becerra; H. C. Breiter; M. Stojanovic; S. Fishman; A. Edwards; A. R. Comite; R. G. Gonzalez; D. Borsook. Human brain activation under controlled thermal stimulation and habituation to noxious heat: an fMRI study. Magnetic Resonance in Medicine 41(5):1044-57, 1999. PMID: 10332889. WOBIB: 72.

+5: 0.37440 Deactivations in romantic love. Viewing of colored pictures of three friends of the same sex as their loved partner versus viewing pictures of the faces of boy- or girlfriend (loved once). WOEXP: 177.
Andreas Bartels; Semir Zeki. The neural basis of romantic love. NeuroReport 11(17):3829-3834, 2000. PMID: 11117499. WOBIB: 54.

+6: 0.37174 Multimodal sensory change. Change between stimuli that are either visual, auditory or tactile. WOEXP: 456.
J. Downar; A. P. Crawley; D. J. Mikulis; K. D. Davis. A multimodal cortical network for the detection of changes in the sensory environment. Nature Neuroscience 3(3):277-283, 2000. PMID: 10700261. DOI: 10.1038/72991. FMRIDCID: . WOBIB: 148.

+7: 0.37040 Pseudoword syllable counting versus case judgment. Counting the number of syllables in a visually presented pseudoword versus decision based on the case of the letters in the word. WOEXP: 556.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

+8: 0.36451 Audio-visual speech low incongruent response. Heard speech and lip movements with sub-additive response to incongruent signals. WOEXP: 474.
Gemma A. Calvert; Ruth Campbell; Michael J. Brammer. Evidence from functional magnetic resonance imaging of crossmodal binding in the human heteromodal cortex. Current Biology 10(11):649-657, 2000. PMID: 10837246. FMRIDCID: . WOBIB: 154.

+9: 0.35962 Nonconscious retrieval of face-word associations. Nonconscious retrieval of brief visual presented face-word pairs where the words indicated occupation during the guessing of the occupation category from faces versus guessing of occupation category from nonconscious viewed faces not associated with occupations. WOEXP: 469.
Katharina Henke; Christian R. A. Mondadori; Valerie Treyer; Roger M. Nitsch; Alfred Buck; Christoph Hock. Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia 41(8):863-876, 2003. PMID: 12667523. FMRIDCID: . WOBIB: 152.

+10: 0.35170 Painful stimulation of the left hand. Painful stimulation of the left hand by laser. WOEXP: 34.
X. Xu; H. Fukuyama; S. Yazawa; T. Mima; T. Hanakawa; Y. Magata; M. Kanda; N. Fujiwara; K. Shindo; T. Nagamine; H. Shibasaki. Functional localization of pain perception in the human brain studied by PET. NeuroReport 8(2):555-559, 1997. PMID: 9080447. WOBIB: 13.

+11: 0.35098 Semantic memory retrieval versus evaluative judgment. Semantic memory retrieval from visually sentences with a yes/no response using right fingers versus evaluative judgment. WOEXP: 377.
Stefan Zysset; Oswald Huber; Evelyn Ferstl; D. Y. von Cramon. The anterior frontomedian cortex and evaluative judgment: an fMRI study. NeuroImage 15(4):983-91, 2002. PMID: 11906238. DOI: 10.1006/nimg.2001.1008. WOBIB: 121.

+12: 0.34767 Increases in rapid auditory processing. Linear increase as a function of compression/presentation speed of auditorily presented sentences that were to be determine semantically true with button press. WOEXP: 524.
Russell A. Poldrack; Elise Temple; Athanassios Protopapas; Srikantan Nagarajan; Paula Tallal; Michael Merzenich; John D. E. Gabrieli. Relations Between the Neural Bases of Dynamic Auditory Processing and Phonological Processing: Evidence from fMRI. Journal of Cognitive Neuroscience 13(5):687-697, 2001. PMID: 11506664. FMRIDCID: 2-2001-111KR. WOBIB: 171.

+13: 0.34570 Deductive reasoning versus probabilistic. Deductive reasoning based on reading three sentence on a screen, two premises and one conclusion, and determining the truth value. WOEXP: 151.
L. M. Parsons; D. Osherson. New Evidence for Distinct Right and Left Brain Systems for Deductive versus Probabilistic Reasoning. Cerebral Cortex 11(10):954-65, 2001. PMID: 11549618. WOBIB: 47.

+14: 0.34055 Cold pain. 5 degree Celsius noxious thermal stimuli with a 3x3cm peltier thermode to the dorsum of the left hand versus 35 degrees stimuli. WOEXP: 182.
I. Tracey; L. Becerra; I. Chang; H. Breiter; L. Jenkins; D. Borsook; R. G. Gonzalez. Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study. Neuroscience Letters 288(2):159-62, 2000. PMID: 10876085. WOBIB: 57.

+15: 0.33877 Newly learned personal names versus newly learned occupation. Retrieval and whispering of newly learned personal names from presented photographs of faces and previously memorized association between face and name. WOEXP: 135.
Takashi Tsukiura; Toshikatsu Fujii; Reiko Fukatsu; Taisuke Otsuki; Jiro Okuda; Atsushi Umetsu; Kyoko Suzuki; Michio Tabuchi; Isao Yanagawa; Tatsuo Nagasaka; Ryuta Kawashima; Hiroshi Fukuda; Shoki Takahashi; Atsushi Yamadori. Neural basis of the retrieval of people's names: evidence from brain-damaged patients and fMRI. Journal of Cognitive Neuroscience 14(6):922-37, 2002. PMID: 12191459. DOI: 10.1162/089892902760191144. FMRIDCID: 2-2002-112QC. WOBIB: 41.

+16: 0.33516 Arabic numerical notation. Arabic notation versus verbal notation of numbers. WOEXP: 24.
P. Pinel; S. Dehaene; D. Riviere; D. LeBihan. Modulation of parietal activation by semantic distance in a number comparison task. NeuroImage 14(5):1013-26, 2001. PMID: 11697933. DOI: 10.1006/nimg.2001.0913. WOBIB: 10.

+17: 0.33502 Syllable counting versus case judgment. Counting the number of syllables in a visually presented word versus decision based on the case of the letters in the word. WOEXP: 552.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

+18: 0.33448 Nonconscious encoding of face-word associations. Nonconscious encoding of brief visual presented face-word pairs where the words indicated occupation versus nonconscious viewing of faces. WOEXP: 467.
Katharina Henke; Christian R. A. Mondadori; Valerie Treyer; Roger M. Nitsch; Alfred Buck; Christoph Hock. Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia 41(8):863-876, 2003. PMID: 12667523. FMRIDCID: . WOBIB: 152.

+19: 0.32971 Heat pain on left hand. Heat pain on dorsal surface of the left hand with and without a Stroop task versus warm. WOEXP: 312.
Brent A. Vogt; Stuart Derbyshire; Anthony K. Jones. Pain processing in four regions of human cingulate cortex localized with co-registered PET and MR imaging. European Journal of Neuroscience 8(7):1461-73, 1996. PMID: 8758953. WOBIB: 100.

+20: 0.32464 Apolipoprotein E e4 allele. CBF in healthy people with apolipoprotein E e4/e4 allele genotype versus controls with e2/e3 or e3/e3 genotype. WOEXP: 344.
Eric M. Reiman; R. J. Caselli; L. S. Yun; K. Chen; D. Bandy; S. Minoshima; S. N. Thibodeau; D. Osborne. Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E. New England Journal of Medicine 334(12):752-8, 1996. PMID: 8592548. WOBIB: 112.

+21: 0.32375 Mildly depressed cancer patients. Cancer patients that might be mildly depressed versus patients with chronic hepatitis. WOEXP: 293.
M. Tashiro; F. D. Juengling; M. J. Reinhardt; I. Brink; S. Hoegerle; M. Mix; K. Kubota; K. Yamaguchi; M. Itoh; H. Sasaki; E. Moser; E. U. Nitzsche. Reproducibility of PET brain mapping of cancer patients. Psychooncology 9(2):157-63, 2000. PMID: 10767753. WOBIB: 92.

+22: 0.32310 Obsessive compulsive disorder, positive correlation. Positive correlation with obsessive compulsive disorder symptom intensities while contaminants placed in folded hands. WOEXP: 323.
Philip K. McGuire; C. J. Bench; C. D. Frith; I. M. Marks; Richard S. J. Frackowiak; R. J. Dolan. Functional anatomy of obsessive-compulsive phenomena. British Journal of Psychiatry 164(4):459-468, 1994. PMID: 8038933. WOBIB: 104.

+23: 0.32135 Feign digit memory impairment. Feigning memory impairment in digit memory versus accurate recall. WOEXP: 124.
Tatia M. C. Lee; Ho-Ling Liu; Li-Hai Tan; Chetwyn C. H. Chan; Srikanth Mahankali; Ching-Mei Feng; Jinwen Hou; Peter T. Fox; Jia-Hong Gao. Lie detection by functional magnetic resonance imaging. Human Brain Mapping 15(3):157-64, 2002. PMID: 11835606. WOBIB: 37.

+24: 0.32002 Pseudoword syllable counting versus semantic judgment via case judgment. Syllable counting of visually presented pseudowords and button press with right hand versus decision whether a visually presented word is abstract or concrete with case judgment as double subtraction. WOEXP: 561.
Russell A. Poldrack; Anthony D. Wagner; Matthew W. Prull; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. Functional Specialization for Sematic and Phonological Processing in the Left Inferior Prefrontal Cortex. NeuroImage 10(1):15-35, 1999. PMID: 10385578. DOI: 10.10061/nimg.1999.0441. FMRIDCID: . WOBIB: 178.

+25: 0.31983 Tics during Tourette's syndrome. Correlation with amount of tics while Tourette patients relaxed with closed eyes. WOEXP: 402.
E. Stern; D. A. Silbersweig; K. Y. Chee; Andrew Holmes; M. M. Robertson; M. Trimble; Christopher D. Frith; Richard S. J. Frackowiak; Raymond J. Dolan. A functional neuroanatomy of tics in Tourette syndrome. Archives of General Psychiatry 57(8):741-748, 2000. PMID: 10920461. FMRIDCID: . WOBIB: 130.


Antirelated - negatively correlated volumes

-1: -0.08961 Mental transformation of size. One-back match-to-sample task with different sized line pattern versus matching of same size line patterns. WOEXP: 100.
A. Larsen; C. Bundesen; S. Kyllingsbaek; O. B. Paulson; I. Law. Brain activation during mental transformation of size. Journal of Cognitive Neuroscience 12(5):763-74, 2000. PMID: 11054919. WOBIB: 30.

-2: -0.08803 Basic level object naming versus fixation. Silent object naming on the "basic" level from visually presented colored pictures versus fixation. WOEXP: 443.
L. K. Tyler; E. A. Stamatakis; P. Bright; K. Acres; S. Abdallah; J. M. Rodd; H. E. Moss. Processing objects at different levels of specificity. Journal of Cognitive Neuroscience 16(3):351-362, 2004. PMID: 15072671. DOI: 10.1162/089892904322926692. FMRIDCID: . WOBIB: 145.

-3: -0.07352 Difficult color matching. Difficult color matching with low discriminable colored random polygons presented serially in pairs on a screen with response on a right or left hand mouse button versus easy color matching. WOEXP: 255.
Claus Bundesen; Axel Larsen; Soren Kyllingsbaek; Olaf B. Paulson; Ian Law. Attentional effects in the visual pathways: a whole-brain PET study. Experimental Brain Research 147(3):394-406, 2002. PMID: 12428147. DOI: 10.1007/s00221-002-1243-1. WOBIB: 81.

-4: -0.07033 Photographs and line drawings of houses versus faces and chairs. Conjunction between delayed match-to sample of gray-scale photographs and line drawings versus scrambled pictures and house versus faces and chairs, with matching choice indicated by pressing a button with the right of left thumb. WOEXP: 93.
A. Ishai; L. G. Ungerleider; A. Martin; J. V. Haxby. The representation of objects in the human occipital and temporal cortex. Journal of Cognitive Neuroscience 12 Suppl 2:35-51, 2000. PMID: 11506646. DOI: 10.1162/089892900564055. FMRIDCID: 2-2000-1113D. WOBIB: 28.

-5: -0.06868 Small line patterns. One-back match-to-sample task with small line patterns versus large line patterns. WOEXP: 102.
A. Larsen; C. Bundesen; S. Kyllingsbaek; O. B. Paulson; I. Law. Brain activation during mental transformation of size. Journal of Cognitive Neuroscience 12(5):763-74, 2000. PMID: 11054919. WOBIB: 30.

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