WOEXP: 291 - Alzheimer's disease versus healthy
 
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Alzheimer's disease versus healthy. Patients with Alzheimer's disease in mental resting state versus matched healthy controls. WOEXP: 291.

Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. American Journal of Psychiatry 159(5):738-45, 2002. PMID: 11986126. WOBIB: 91.

Disease - Alzheimer's disease
WOEXT: 219.

Modality:PET
Measured variable: CMRGlu
Tracer: F-18 2-deoxy-2-fluro-D-glucose (FDG)
Scanner: Scanditronix, PC4096-7B
Number of subjects: 48

Asymmetry: 0.00000 (left: -1, right: +1)

  x     y     z   Lobar anatomy Functional area WOROI Value
-44 6 37 Left midfrontal      
-28 23 39 Left midfrontal      
55 4 37 Right midfrontal      
44 19 40 Right midfrontal      
-51 -53 21 Left superior temporal      
50 -40 13 Right superior temporal      
-50 -54 14 Left midtemporal      
50 -60 14 Right midtemporal      
-46 -72 4 Left inferior temporal      
46 -64 3 Right inferior temporal      
-28 -57 -4 Left fusiform      
30 -49 -4 Right fusiform      
-28 -56 -1 Left lingual      
30 -51 -1 Right lingual      
-36 -35 -5 Left parahippocampal      
34 -37 -5 Right parahippocampal      
-48 -56 43 Left inferior parietal      
-50 -55 25 Left inferior parietal      
53 -52 43 Right inferior parietal      
51 -57 25 Right inferior parietal      
-8 -70 44 Left precuneus      
6 -68 44 Right precuneus      
-6 -47 24 Posterior cingulate      
4 -53 21 Posterior cingulate      
-38 -76 26 Left occipital      
38 -82 30 Right occipital      
-44 -77 15 Left midoccipital      
38 -85 15 Right midoccipital      
-32 -93 1 Left inferior occipital      
30 -95 1 Right inferior occipital      

corner cube of volume 291 (Alzheimer's disease versus
      healthy)

[ PNG | VRML (156Kb) ]

Related - positive correlated volumes

+1: 1.00000 Alzheimer's disease versus healthy. Patients with Alzheimer's disease in mental resting state versus matched healthy controls. WOEXP: 291.
Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. American Journal of Psychiatry 159(5):738-45, 2002. PMID: 11986126. WOBIB: 91.

+2: 0.61227 Coherent visual motion. Coherent visual motion of dots versus static display of dots. WOEXP: 112.
E. Grossman; M. Donnelly; R. Price; D. Pickens; V. Morgan; G. Neighbor; R. Blake. Brain areas involved in perception of biological motion. Journal of Cognitive Neuroscience 12(5):711-20, 2000. PMID: 11054914. WOBIB: 33.

+3: 0.56457 Biological visual motion. Biological motion of dots versus scrambled motion of dots. WOEXP: 111.
E. Grossman; M. Donnelly; R. Price; D. Pickens; V. Morgan; G. Neighbor; R. Blake. Brain areas involved in perception of biological motion. Journal of Cognitive Neuroscience 12(5):711-20, 2000. PMID: 11054914. WOBIB: 33.

+4: 0.56044 Activation in amusement film viewing versus sadness film viewing. Passive viewing of 2.5 minute emotional film clips. WOEXP: 281.
S. Aalto; P. Naatanen; E. Wallius; L. Metsahonkala; H. Stenman; P. M. Niem; H. Karlsson. Neuroanatomical substrata of amusement and sadness: a PET activation study using film stimuli. NeuroReport 13(1):67-73, 2002. PMID: 11924897. WOBIB: 88.

+5: 0.55438 Visual motion. Visual motion by viewing 100 small moving black squares versus stationary dots. WOEXP: 430.
Semir Zeki; J. D. Watson; C. J. Lueck; Karl J. Friston; C. Kennard; Richard S. J. Frackowiak. A direct demonstration of functional specialization in human visual cortex. Journal of Neuroscience 11(3):641-649, 1991. PMID: 2002358. FMRIDCID: . WOBIB: 140.

+6: 0.52842 Bimodal audiovisual speech-reading. Simultaneous hearing and seeing with lip-reading of digits versus unimodal viewing or unimodal hearing digits. WOEXP: 499.
Gemma A. Calvert; Michael J. Brammer; Edward T. Bullmore; Ruth Campbell; S. D. Iversen; Anthony S. David. Response amplification in sensory-specific cortices during crossmodal binding. NeuroReport 10(12):2619-2623, 1999. PMID: 10574380. FMRIDCID: . WOBIB: 164.

+7: 0.52544 Photographs of chairs versus houses and faces. Conjunction between passive viewing and delayed match-to sample of gray-scale photographs versus scrambled pictures and chairs versus houses and faces, with matching choice indicated by pressing a button with the right of left thumb. WOEXP: 92.
A. Ishai; L. G. Ungerleider; A. Martin; J. V. Haxby. The representation of objects in the human occipital and temporal cortex. Journal of Cognitive Neuroscience 12 Suppl 2:35-51, 2000. PMID: 11506646. DOI: 10.1162/089892900564055. FMRIDCID: 2-2000-1113D. WOBIB: 28.

+8: 0.51029 Activation in amusement film viewing versus neutral film viewing. Passive viewing of 2.5 minute emotional film clips. WOEXP: 279.
S. Aalto; P. Naatanen; E. Wallius; L. Metsahonkala; H. Stenman; P. M. Niem; H. Karlsson. Neuroanatomical substrata of amusement and sadness: a PET activation study using film stimuli. NeuroReport 13(1):67-73, 2002. PMID: 11924897. WOBIB: 88.

+9: 0.50005 Moving dots versus stationary dots. 250 white dots moved radially from the fixation point in the middle of the screen in random directions towards the border of the screen. WOEXP: 76.
Christian Büchel; Oliver Josephs; Geraint Rees; R. Turner; C. D. Frith; Karl J. Friston. The functional anatomy of attention to visual motion. A functional MRI study. Brain 121 ( Pt 7):1281-94, 1998. PMID: 9679780. WOBIB: 24.

+10: 0.48341 Attention to musical instruments versus attention to consonant-vowels. Attend to sound and press a button when the target stimulus appeared. WOEXP: 42.
K. Hugdahl; Ian Law; S. Kyllingsbaek; K. Bronnick; Anders Gade; Olaf B. Paulson. Effects of attention on dichotic listening: an 15O-PET study. Human Brain Mapping 10(2):87-97, 2000. PMID: 10864233. WOBIB: 14.

+11: 0.47864 Rest versus word generation. Resting with eyes closed versus generate words covertly without articulation cued with letter or category. WOEXP: 585.
Eraldo Paulesu; Ben Goldacre; Paola Scifo; Stefano F. Cappa; Maria Carla Gilardi; Isabella Castiglioni; Daniela Perani; Frruccio Fazio. Functional heterogeneity of left inferior frontal cortex as revealed by fMRI. NeuroReport 8(8):2011-2017, 1997. PMID: 9223094. FMRIDCID: . WOBIB: 185.

+12: 0.47070 Obsessive compulsive disorder, negative correlation. Negative correlation with obsessive compulsive disorder symptom intensities while contaminants placed in folded hands. WOEXP: 324.
Philip K. McGuire; C. J. Bench; C. D. Frith; I. M. Marks; Richard S. J. Frackowiak; R. J. Dolan. Functional anatomy of obsessive-compulsive phenomena. British Journal of Psychiatry 164(4):459-468, 1994. PMID: 8038933. WOBIB: 104.

+13: 0.44885 Resting versus novel word recall. Resting versus speak load words recalled from a list of 15 words heard only one time just prior to recall. WOEXP: 274.
Nancy C. Andreasen; D. S. O'Leary; T. Cizadlo; Stephan Arndt; K. Rezai; G. L. Watkins; L. L. Ponto; R. D. Hichwa. II. PET studies of memory: novel versus practiced free recall of word lists. NeuroImage 2(4):296-305, 1995. PMID: 9343614. WOBIB: 85.

+14: 0.44775 Visual human body perception during free viewing. Subjective experience of visual human body perception during free viewing and hearing of a James Bond movie. WOEXP: 384.
Andreas Bartels; Semir Zeki. Functional brain mapping during free viewing of natural scenes. Human Brain Mapping 21(2):75-85, 2004. PMID: 14755595. DOI: 10.1002/hbm.10153. WOBIB: 123.

+15: 0.44702 Various visual motion stimuli. Various first and second order motion stimuli versus stationary visual stimuli. WOEXP: 175.
A. T. Smith; M. W. Greenlee; K. D. Singh; F. M. Kraemer; J. Hennig. The processing of first- and second-order motion in human visual cortex assessed by functional magnetic resonance imaging (fMRI). Journal of Neuroscience 18(10):3816-30, 1998. PMID: 9570811. WOBIB: 53.

+16: 0.44537 Harm avoidance and D2 5HT2A negative correlation. Negative correlation between harm avoidance assess with Cloninger's Tridimensional Personality Questionnaire and FESP binding to dopamine D2 and serotonin 5HT2A receptors. WOEXP: 493.
Rosa Maria Moresco; M. Dieci; A. Vita; Christina Messa; C. Gobbo; L. Galli; Giovanna Rizzo; A. Panzacchi; L. De Peri; G. Invernizzi; Ferruchio Fazio. In vivo serotonin 5HT(2A) receptor binding and personality traits in healthy subjects: a positron emission tomography study. NeuroImage 17(3):1470-1478, 2002. PMID: 12414286. FMRIDCID: . WOBIB: 161.

+17: 0.44449 Face perception during free viewing. Subjective experience of face perception during free viewing of a James Bond movie. WOEXP: 382.
Andreas Bartels; Semir Zeki. Functional brain mapping during free viewing of natural scenes. Human Brain Mapping 21(2):75-85, 2004. PMID: 14755595. DOI: 10.1002/hbm.10153. WOBIB: 123.

+18: 0.43956 Audio-visual speech with high congruent response. Heard speech and lip movements with supra-additive response to congruent signals. WOEXP: 473.
Gemma A. Calvert; Ruth Campbell; Michael J. Brammer. Evidence from functional magnetic resonance imaging of crossmodal binding in the human heteromodal cortex. Current Biology 10(11):649-657, 2000. PMID: 10837246. FMRIDCID: . WOBIB: 154.

+19: 0.43675 Relative metabolic decreases in Alzheimer's disease. Relative metabolic differences between Alzheimer's disease patients and controls. WOEXP: 191.
Nora D. Volkow; Wei Zhu; Christoph A. Felder; Klaus Mueller; Tomihisa F. Welsh; Gene J. Wang; Mony J. de Leon. Changes in brain functional homogeneity in subjects with Alzheimer's disease. Psychiatry Research 114(1):39-50, 2002. PMID: 11864808. WOBIB: 61.

+20: 0.43215 Regions correlating with superior colliculus activity. Regions correlating with superior colliculus activity under the condition of visual search but not saccadic eye movements. WOEXP: 8.
Darren R. Gitelman; Todd B. Parrish; Karl J. Friston; M-Marsel Mesulam. Functional anatomy of visual search: regional segregations within the frontal eye fields and effective connectivity of the superior colliculus. NeuroImage 15(4):970-82, 2002. PMID: 11906237. DOI: 10.1006/nimg.2001.1006. WOBIB: 3.

+21: 0.42920 Photographs and line drawings of chairs versus houses and faces. Conjunction between delayed match-to sample of gray-scale photographs and line drawings versus scrambled pictures and chairs versus houses and faces, with matching choice indicated by pressing a button with the right of left thumb. WOEXP: 95.
A. Ishai; L. G. Ungerleider; A. Martin; J. V. Haxby. The representation of objects in the human occipital and temporal cortex. Journal of Cognitive Neuroscience 12 Suppl 2:35-51, 2000. PMID: 11506646. DOI: 10.1162/089892900564055. FMRIDCID: 2-2000-1113D. WOBIB: 28.

+22: 0.42833 Photographs of faces versus houses and chairs. Conjunction between passive viewing and delayed match-to sample of gray-scale photographs versus scrambled pictures and faces versus houses and chairs, with matching choice indicated by pressing a button with the right of left thumb. WOEXP: 91.
A. Ishai; L. G. Ungerleider; A. Martin; J. V. Haxby. The representation of objects in the human occipital and temporal cortex. Journal of Cognitive Neuroscience 12 Suppl 2:35-51, 2000. PMID: 11506646. DOI: 10.1162/089892900564055. FMRIDCID: 2-2000-1113D. WOBIB: 28.

+23: 0.42276 Fearful face recognition with placebo drug. Fearful face recognition after placebo infusion versus neutral face recognition after placebo infusion. WOEXP: 475.
Kathryn M. Abel; Matthew P. G. Allin; Katarzyna Kucharska-Pietura; Anthony S. David; Chris Andrew; Steven C. R. Williams; Michael J. Brammer; Mary L. Phillips. Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study. NeuroReport 14(3):387-391, 2003. PMID: 12634489. DOI: 10.1097/01.wnr.0000058031.29600.31. FMRIDCID: . WOBIB: 155.

+24: 0.41521 Skill learning: Early mirror-reading versus late mirror-reading. Lexical decision task determining word or non-word on visually presented either plain text or mirror-reversed text. WOEXP: 45.
Russell A. Poldrack; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. The neural basis of visual skill learning: an fMRI study of mirror reading. Cerebral Cortex 8(1):1-10, 1998. PMID: 9510380. WOBIB: 15.

+25: 0.41338 Silent reading of proper words versus rest. Silent reading of visually presented proper words versus resting. WOEXP: 395.
Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI. Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000. PMID: 11506654. DOI: 10.1162/089892900564000. FMRIDCID: 2-2000-11189. WOBIB: 129.


Antirelated - negatively correlated volumes

-1: -0.09276 Heat pain in left forearm versus thermal stimulus. 47-48 degrees painful heat on ventral surface of left forearm versus 34 degrees stimulus. WOEXP: 362.
R. C. Coghill; J. D. Talbot; A. C. Evans; Ernst Meyer; Albert Gjedde; M. C. Bushnell; G. H. Duncan. Distributed processing of pain and vibration by the human brain. Journal of Neuroscience 14(7):4095-108, 1994. PMID: 8027764. WOBIB: 117.

-2: -0.09275 Chronic facial pain versus no pain after thalamic stimulation. Chronic pain in the right side of the face versus no pain after thalamic stimulation in the left ventroposterior medial thalamic nucleus (-7, -20, +2). WOEXP: 193.
Ron C. Kupers; J. M. Gybels; Albert Gjedde. Positron emission tomography study of a chronic pain patient successfully treated with somatosensory thalamic stimulation. Pain 87(3):295-302, 2000. PMID: 10963909. WOBIB: 62.

-3: -0.09254 Happy versus neutral. Recalling of powerful and personal autobiographical emotional episodes invoking happiness versus recalling emotionally neutral life episodes. WOEXP: 484.
Mario Pelletier; Alain Bouthillier; Johanne Levesque; Serge Carrier; Claude Breault; Vincent Paquette; Boualem Mensour; Jean-Maxime Leroux; Gilles Beaudoin; Pierre Bourgouin; Mario Beauregard. Separate neural circuits for primary emotions? Brain activity during self-induced sadness and happiness in professional actors. NeuroReport 14(8):1111-1116, 2003. PMID: 12821792. DOI: 10.1097/01.wnr.0000075421.59944.69. FMRIDCID: . WOBIB: 157.

-4: -0.08836 Sad versus neutral. Recalling of powerful and personal autobiographical emotional episodes invoking sadness versus recalling emotionally neutral life episodes. WOEXP: 483.
Mario Pelletier; Alain Bouthillier; Johanne Levesque; Serge Carrier; Claude Breault; Vincent Paquette; Boualem Mensour; Jean-Maxime Leroux; Gilles Beaudoin; Pierre Bourgouin; Mario Beauregard. Separate neural circuits for primary emotions? Brain activity during self-induced sadness and happiness in professional actors. NeuroReport 14(8):1111-1116, 2003. PMID: 12821792. DOI: 10.1097/01.wnr.0000075421.59944.69. FMRIDCID: . WOBIB: 157.

-5: -0.08055 Smelling. Smelling birhinally to eight different odorants versus smelling to odourless cotton wand. WOEXP: 487.
Robert J. Zatorre; Marilyn Jones-Gotman; Alan C. Evans; Ernst Meyer. Functional localization and lateralization of human olfactory cortex. Nature 360(6402):339-340, 1992. PMID: 1448149. DOI: 10.1038/360339a0. FMRIDCID: . WOBIB: 158.

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