WOEXP: 249 - Correlation with pain unpleasantness
 
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Correlation with pain unpleasantness. Correlation with subjective ratings of unpleasantness with hot pain right volar forearm. WOEXP: 249.

T. R. Tolle; T. Kaufmann; T. Siessmeier; S. Lautenbacher; A. Berthele; F. Munz; W. Zieglgansberger; F. Willoch; M. Schwaiger; B. Conrad; P. Bartenstein. Region-specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis. Annals of Neurology 45(1):40-47, 1999. PMID: 9894875. WOBIB: 79.

Perception,Somesthesis - Pain
Perception,Somesthesis - Temperature
WOEXT: 69.

Modality:PET/MRI
Measured variable: CBF
Tracer: O-15 Water
Scanner: Siemens, 951 R/31
Number of subjects: 12

Asymmetry: -0.50000 (left: -1, right: +1)

  x     y     z   Lobar anatomy Functional area WOROI Value
-6 -8 30 Left anterior cingulate cortex      

corner cube of volume 249 (Correlation with pain unpleasantness)

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Related - positive correlated volumes

+1: 1.00000 Correlation with pain unpleasantness. Correlation with subjective ratings of unpleasantness with hot pain right volar forearm. WOEXP: 249.
T. R. Tolle; T. Kaufmann; T. Siessmeier; S. Lautenbacher; A. Berthele; F. Munz; W. Zieglgansberger; F. Willoch; M. Schwaiger; B. Conrad; P. Bartenstein. Region-specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis. Annals of Neurology 45(1):40-47, 1999. PMID: 9894875. WOBIB: 79.

+2: 0.88585 Hot pain in 1 second for P750 component. Dipole source for the P750 event-related potential component associated with hot pain during 1 seconds. WOEXP: 422.
Andrew C. N. Chen; David M. Niddam; Helen J. Crawford; Robert Oostenveld; Lars Arendt-Nielsen. Spatial summation of pain processing in the human brain as assessed by cerebral event related potentials. Neuroscience Letters 328(2):190-194, 2002. PMID: 12133585. FMRIDCID: . WOBIB: 136.

+3: 0.71730 Hot pain in 2 second for P750 component. Dipole source for the P750 event-related potential component associated with hot pain during 2 seconds. WOEXP: 423.
Andrew C. N. Chen; David M. Niddam; Helen J. Crawford; Robert Oostenveld; Lars Arendt-Nielsen. Spatial summation of pain processing in the human brain as assessed by cerebral event related potentials. Neuroscience Letters 328(2):190-194, 2002. PMID: 12133585. FMRIDCID: . WOBIB: 136.

+4: 0.63006 Positive correlation to electrodermal activity. Correlation to nonspecific skin conductance fluctuation on the palmar side of the second phalanx of the left hand during viewing of aversive and nonaversive movies and with and without electrical shocks to the right fingers. WOEXP: 296.
M. Fredrikson; T. Furmark; M. T. Olsson; Håkan Fischer; J. Andersson; B. Langstrom. Functional neuroanatomical correlates of electrodermal activity: a positron emission tomographic study. Psychophysiology 35(2):179-85, 1998. PMID: 9529944. WOBIB: 94.

+5: 0.59825 Heat pain. 48 to 49 degrees heat pain on the right volar forearm versus 41 to 42 warm stimulus. WOEXP: 346.
J. D. Talbot; S. Marrett; Alan C. Evans; Ernst Meyer; M. C. Bushnell; G. H. Duncan. Multiple representations of pain in human cerebral cortex. Science 251(4999):1355-8, 1991. PMID: 2003220. BrainMap: 5. WOBIB: 114.

+6: 0.59378 Increase during viewing conditioned snake and spider video. Viewing snake and spider video conditioned with an electric shock to the second phalanx of the right index and long fingers versus viewing video before conditioning. WOEXP: 310.
M. Fredrikson; G. Wik; Håkan Fischer; J. Andersson. Affective and attentive neural networks in humans: a PET study of Pavlovian conditioning. NeuroReport 7(1):97-101, 1995. PMID: 8742426. WOBIB: 99.

+7: 0.52272 Visuospatial attention. Visuospatial attention with directional cue either by central expectancy where a central diamond indicated left/right cue or by a change in luminance in a peripheral square. WOEXP: 371.
M. M. Mesulam; A. C. Nobre; Y. H. Kim; T. B. Parrish; D. R. Gitelman. Heterogeneity of cingulate contributions to spatial attention. NeuroImage 13(6 Pt 1):1065-72, 2001. PMID: 11352612. DOI: 10.1006/nimg.2001.0768. WOBIB: 120.

+8: 0.46044 Neutral face viewing versus happy face viewing. Viewing neutral emotional face and indication with a button press versus viewing happy faces. WOEXP: 308.
Mary L. Phillips; E. T. Bullmore; R. Howard; P. W. Woodruff; I. C. Wright; Steven C. R. Williams; A. Simmons; C. Andrew; M. Brammer; Anthony S. David. Investigation of facial recognition memory and happy and sad facial expression perception: an fMRI study. Psychiatry Research 83(3):127-38, 1998. PMID: 9849722. WOBIB: 98.

+9: 0.45588 Cold pain versus cold pain with silent word reading. 0-2 centigrades cold pain on dorsal surface of the right foot versus cold pain distracted by silent word. WOEXP: 266.
U. N. Frankenstein; W. Richter; M. C. McIntyre; F. Remy. Distraction modulates anterior cingulate gyrus activations during the cold pressor test. NeuroImage 14(4):827-36, 2001. PMID: 11554801. DOI: 10.1006/nimg.2001.0883. WOBIB: 83.

+10: 0.44194 Negative correlation with pain threshold. . WOEXP: 247.
T. R. Tolle; T. Kaufmann; T. Siessmeier; S. Lautenbacher; A. Berthele; F. Munz; W. Zieglgansberger; F. Willoch; M. Schwaiger; B. Conrad; P. Bartenstein. Region-specific encoding of sensory and affective components of pain in the human brain: a positron emission tomography correlation analysis. Annals of Neurology 45(1):40-47, 1999. PMID: 9894875. WOBIB: 79.

+11: 0.43493 Cold pain on left arm. 6 degrees heat pain stimuli by immersion of the left hand in water to the wrist versus 20 degrees stimuli. WOEXP: 320.
K. L. Casey; S. Minoshima; T. J. Morrow; R. A. Koeppe. Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain. Journal of Neurophysiology 76(1):571-81, 1996. PMID: 8836245. WOBIB: 102.

+12: 0.42113 Neutral face recognition with ketamine versus fearful with placebo drug. Neutral face recognition after ketamine-induced emotional blunting versus with placebo infusion and fearful face recognition after ketamine infusion. WOEXP: 480.
Kathryn M. Abel; Matthew P. G. Allin; Katarzyna Kucharska-Pietura; Anthony S. David; Chris Andrew; Steven C. R. Williams; Michael J. Brammer; Mary L. Phillips. Ketamine alters neural processing of facial emotion recognition in healthy men: an fMRI study. NeuroReport 14(3):387-391, 2003. PMID: 12634489. DOI: 10.1097/01.wnr.0000058031.29600.31. FMRIDCID: . WOBIB: 155.

+13: 0.39542 Pointing to previous target versus fixation. Movement of a stylus with the right hand for the movement of a screen cursor from a central fixation point to a target in the periphery shown in the previous round versus passive fixation. WOEXP: 574.
F. Lacquaniti; Daniela Perani; E. Guigon; V. Bettinardi; M. Carrozzo; F. Grassi; Yves Rossetti; F. Fazio. Visuomotor Transformations for Reaching to Memorized Targets: A PET study. NeuroImage 5(2):129-146, 1997. PMID: 9345543. DOI: 10.1006.nimg.1996.0254. FMRIDCID: . WOBIB: 182.

+14: 0.35196 Increased activity during REM sleep. REM sleep versus slow-wave sleep or wakefull-state. WOEXP: 300.
P. Maquet; J. Peters; J. Aerts; G. Delfiore; C. Degueldre; A. Luxen; G. Franck. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming. Nature 383(6596):163-6, 1996. PMID: 8774879. WOBIB: 96.

+15: 0.33436 Warmth on left hand (group 1). 41 degrees warm stimuli to the dorsum of the left hand versus 35 degree stimuli. WOEXP: 226.
L. R. Becerra; H. C. Breiter; M. Stojanovic; S. Fishman; A. Edwards; A. R. Comite; R. G. Gonzalez; D. Borsook. Human brain activation under controlled thermal stimulation and habituation to noxious heat: an fMRI study. Magnetic Resonance in Medicine 41(5):1044-57, 1999. PMID: 10332889. WOBIB: 72.

+16: 0.32737 Late phase heat pain. 50 degrees Celsius heat on the left volar forearm starting 40 seconds prior to the scanning onset versus 40 degrees warm stimulus. WOEXP: 299.
K. L. Casey; T. J. Morrow; J. Lorenz; S. Minoshima. Temporal and spatial dynamics of human forebrain activity during heat pain: analysis by positron emission tomography. Journal of Neurophysiology 85(2):951-9, 2001. PMID: 11160525. WOBIB: 95.

+17: 0.32703 Practiced word recall versus novel word recall. Speak load words recalled from a list of 15 words practiced one week before versus speak words aloud from a list of words heard just prior to recall. WOEXP: 276.
Nancy C. Andreasen; D. S. O'Leary; T. Cizadlo; Stephan Arndt; K. Rezai; G. L. Watkins; L. L. Ponto; R. D. Hichwa. II. PET studies of memory: novel versus practiced free recall of word lists. NeuroImage 2(4):296-305, 1995. PMID: 9343614. WOBIB: 85.

+18: 0.32417 Visual pursuit tracking. Visual pursuit tracking eye movement by following a white spot on a screen moving sinusoidal along the horizontal meridian versus central fixation. WOEXP: 149.
R. A. Berman; C. L. Colby; C. R. Genovese; J. T. Voyvodic; B. Luna; K. R. Thulborn; J. A. Sweeney. Cortical networks subserving pursuit and saccadic eye movements in humans: an FMRI study. Human Brain Mapping 8(4):209-25, 1999. PMID: 10619415. WOBIB: 46.

+19: 0.32356 Active elbow movement versus passive movement. Active flexion and extension movements of the elbow of the right arm paced by a metronome versus passive movement. WOEXP: 464.
C. Weiller; M. Juptner; S. Fellows; M. Rijntjes; G. Leonhardt; S. Kiebel; S. Muller; H. C. Diener; A. F. Thilmann. Brain representation of active and passive movements. NeuroImage 4(2):105-110, 1996. PMID: 9345502. FMRIDCID: . WOBIB: 151.

+20: 0.32348 Heat pain on left arm. 50 degrees heat pain stimuli on six separate sites on the left volar forearm versus 40 degrees stimuli. WOEXP: 319.
K. L. Casey; S. Minoshima; T. J. Morrow; R. A. Koeppe. Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain. Journal of Neurophysiology 76(1):571-81, 1996. PMID: 8836245. WOBIB: 102.

+21: 0.31722 Visuospatial attention with cue effect to valid cues. Visuospatial attention with directional cue either by central expectancy where a central diamond indicated left/right cue or by a change in luminance in a peripheral square, and with cue effect to valid cue. WOEXP: 372.
M. M. Mesulam; A. C. Nobre; Y. H. Kim; T. B. Parrish; D. R. Gitelman. Heterogeneity of cingulate contributions to spatial attention. NeuroImage 13(6 Pt 1):1065-72, 2001. PMID: 11352612. DOI: 10.1006/nimg.2001.0768. WOBIB: 120.

+22: 0.31177 Attended heat pain on right hand. 46 to 49 degrees Celsius hot stimuli on the thenar eminence of the right hand using a peltier thermode versus 40 degrees warm stimuli. WOEXP: 186.
Jonathan C. W. Brooks; Turo J. Nurmikko; William E. Bimson; Krish D. Singh; Neil Roberts. fMRI of thermal pain: effects of stimulus laterality and attention. NeuroImage 15(2):293-301, 2002. PMID: 11798266. DOI: 10.1006/nimg.2001.0974. WOBIB: 60.

+23: 0.30959 Cold pain in left hand. Left hand immersed in cold circulating water with a temperature of 0-0.5 degrees Celsius while either fixating or engaged in a externally driven perceptual maze task versus immersion in 19 degrees Celsius water and fixating or performing the maze task. WOEXP: 184.
P. Petrovic; K. M. Petersson; P. H. Ghatan; S. Stone-Elander; M. Ingvar. Pain-related cerebral activation is altered by a distracting cognitive task. Pain 85(1-2):19-30, 2000. PMID: 10692599. WOBIB: 58.

+24: 0.29187 Cold pain. 5 degree Celsius noxious thermal stimuli with a 3x3cm peltier thermode to the dorsum of the left hand versus 35 degrees stimuli. WOEXP: 182.
I. Tracey; L. Becerra; I. Chang; H. Breiter; L. Jenkins; D. Borsook; R. G. Gonzalez. Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study. Neuroscience Letters 288(2):159-62, 2000. PMID: 10876085. WOBIB: 57.

+25: 0.28229 Unpleasant words. Silent judgement of auditorily presented unpleasant arousing words versus matched neutral words. WOEXP: 132.
Richard J. Maddock; Amy S. Garrett; Michael H. Buonocore. Posterior cingulate cortex activation by emotional words: fMRI evidence from a valence decision task. Human Brain Mapping 18(1):30-41, 2003. PMID: 12454910. DOI: 10.1002/hbm.10075. WOBIB: 39.


Antirelated - negatively correlated volumes

-1: -0.04121 Skill learning: Early mirror-reading versus late mirror-reading. Lexical decision task determining word or non-word on visually presented either plain text or mirror-reversed text. WOEXP: 45.
Russell A. Poldrack; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. The neural basis of visual skill learning: an fMRI study of mirror reading. Cerebral Cortex 8(1):1-10, 1998. PMID: 9510380. WOBIB: 15.

-2: -0.03416 Alzheimer's disease versus healthy. Patients with Alzheimer's disease in mental resting state versus matched healthy controls. WOEXP: 291.
Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. American Journal of Psychiatry 159(5):738-45, 2002. PMID: 11986126. WOBIB: 91.

-3: -0.03363 Visuospatial 2-back, Pittsburgh site. Viewing of dots in one of four displayed boxes with button pressing for indicating where the dot occured two trials back versus pressing buttons in zero-back. WOEXP: 355.
B. J. Casey; Jonathan D. Cohen; K. O'Craven; Richard J. Davidson; W. Irwin; C. A. Nelson; D. C. Noll; X. Hu; M. J. Lowe; B. R. Rosen; C. L. Truwitt; P. A. Turski. Reproducibility of fMRI results across four institutions using a spatial working memory task. NeuroImage 8(3):249-261, 1998. PMID: 9758739. FMRIDCID: . WOBIB: 116.

-4: -0.03255 Reflection on famous third person personality traits. Reflection on personality traits of famous third person versus reflection on one's own personality traits. WOEXP: 104.
Troels Kjaer; Markus Nowak; Hans Lou. Reflective Self-Awareness and Conscious States: PET Evidence for a Common Midline Parietofrontal Core. NeuroImage 17(2):1080, 2002. PMID: 12377180. WOBIB: 31.

-5: -0.03247 Activation in amusement film viewing versus neutral film viewing. Passive viewing of 2.5 minute emotional film clips. WOEXP: 279.
S. Aalto; P. Naatanen; E. Wallius; L. Metsahonkala; H. Stenman; P. M. Niem; H. Karlsson. Neuroanatomical substrata of amusement and sadness: a PET activation study using film stimuli. NeuroReport 13(1):67-73, 2002. PMID: 11924897. WOBIB: 88.

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