WOBIB: 99 - Fredrikson, et al. (1995) Affective and att ...
 
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M. Fredrikson; G. Wik; Håkan Fischer; J. Andersson. Affective and attentive neural networks in humans: a PET study of Pavlovian conditioning. NeuroReport 7(1):97-101, 1995. PMID: 8742426. WOBIB: 99.

Using positron emission tomography (PET) and [15O]butanol we studied regional cerebral blood flow (rCBF) to a visual snake stimulus before and after classical conditioning with an unconditioned electric shock delivered to the right hand. Measures of heart rate, electrodermal activity, state anxiety and subjective distress confirmed classical conditioning of physiological and subjective responses. Subcortically, conditioning increased rCBF bilaterally in the ventromedial thalamus, the posterior hypothalamus and the central grey of the midbrain. Cortically, rCBF increased in the left anterior and posterior cingulate gyrus, the left primary somatosensory cortex, the left premotor cortex and bilaterally in parietal areas. Thus, the functional organization of classical conditioning in humans involves autonomic, affective and attentive brain mechanisms.

Asymmetry: -0.93457 (left: -1, right: +1)

VRML2 file (73 Kb)

1 Increase during viewing conditioned snake and spider video. Viewing snake and spider video conditioned with an electric shock to the second phalanx of the right index and long fingers versus viewing video before conditioning. WOEXP: 310.
2 Decrease during viewing conditioned snake and spider video. Decrease in activation during viewing snake and spider video conditioned with an electric shock to the second phalanx of the right index and long fingers versus viewing video before conditioning. WOEXP: 311.


corner cube of WOBIB_99

Related - positive correlated volumes

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