WOBIB: 140 - Zeki, et al. (1991) A direct demonstration ...
Bib -> Asymmetry | Author | ICA | NMF | Novelty | Statistics | SVD | Title | WOBIB ]
Exp -> Alphabetic | Asymmetry | ICA | NMF | Novelty | SVD | WOEXP | WOEXT ]
Ext -> Alphabetic index | Map | Roots ]          [ Brede ]          Loc -> Statistics ]

Semir Zeki; J. D. Watson; C. J. Lueck; Karl J. Friston; C. Kennard; Richard S. J. Frackowiak. A direct demonstration of functional specialization in human visual cortex. Journal of Neuroscience 11(3):641-649, 1991. PMID: 2002358. FMRIDCID: . WOBIB: 140.

We have used positron emission tomography (PET), which measures regional cerebral blood flow (rCBF), to demonstrate directly the specialization of function in the normal human visual cortex. A novel technique, statistical parametric mapping, was used to detect foci of significant change in cerebral blood flow within the prestriate cortex, in order to localize those parts involved in the perception of color and visual motion. For color, we stimulated the subjects with a multicolored abstract display containing no recognizable objects (Land color Mondrian) and contrasted the resulting blood flow maps with those obtained when subjects viewed an identical display consisting of equiluminous shades of gray. The comparison identified a unique area (area V4) located in the lingual and fusiform gyri of the prestriate cortex. For motion, blood flow maps when subjects viewed moving or stationary black and white random-square patterns were contrasted. The comparison identified a unique area located in the region of the temporo-parieto-occipital junction (area V5). We thus provide direct evidence to show that, just as in the macaque monkey, different areas of the human prestriate visual cortex are specialized for different attributes of vision. The striate cortex (V1) and the contiguous visual area (V2), which in the monkey brain feed both the homologous areas, were active in all 4 conditions. This pattern of activity allowed us to use an extension of the approach to assess the functional relationship between the 3 areas during color and motion stimulation. This is based on an hypothesis-led analysis of the covariance structure of the blood flow maps and promises to be a powerful tool for inferring anatomical pathways in the normal human brain. In this study, we were able to demonstrate a positive functional relationship between areas V1/V2 and V4 during color vision and areas V1/V2 and V5 during motion stimulation, reflecting the anatomical connections between these areas in the macaque monkey.

Asymmetry: -0.31250 (left: -1, right: +1)

VRML2 file (62 Kb)

1 Vision. Vision by viewing a Mondrian-like images with a collage of colored or gray squares and rectangles of different shapes versus eyes closed. WOEXP: 428.
2 Color vision. Color vision by viewing a Mondrian-like with a collage of colored squares and rectangles of different shapes and colors versus colorless Mondrian image with isoluminant gray values. WOEXP: 429.
3 Visual motion. Visual motion by viewing 100 small moving black squares versus stationary dots. WOEXP: 430.

corner cube of WOBIB_140

Related - positive correlated volumes

+1: 1.00000 Semir Zeki; J. D. Watson; C. J. Lueck; Karl J. Friston; C. Kennard; Richard S. J. Frackowiak. A direct demonstration of functional specialization in human visual cortex. Journal of Neuroscience 11(3):641-649, 1991. PMID: 2002358. FMRIDCID: . WOBIB: 140.

+2: 0.59815 Darren R. Gitelman; Todd B. Parrish; Karl J. Friston; M-Marsel Mesulam. Functional anatomy of visual search: regional segregations within the frontal eye fields and effective connectivity of the superior colliculus. NeuroImage 15(4):970-82, 2002. PMID: 11906237. DOI: 10.1006/nimg.2001.1006. WOBIB: 3.

+3: 0.57447 A. T. Smith; M. W. Greenlee; K. D. Singh; F. M. Kraemer; J. Hennig. The processing of first- and second-order motion in human visual cortex assessed by functional magnetic resonance imaging (fMRI). Journal of Neuroscience 18(10):3816-30, 1998. PMID: 9570811. WOBIB: 53.

+4: 0.54136 A. Ishai; L. G. Ungerleider; A. Martin; J. V. Haxby. The representation of objects in the human occipital and temporal cortex. Journal of Cognitive Neuroscience 12 Suppl 2:35-51, 2000. PMID: 11506646. DOI: 10.1162/089892900564055. FMRIDCID: 2-2000-1113D. WOBIB: 28.

+5: 0.50681 Russell A. Poldrack; John E. Desmond; Gary H. Glover; John D. E. Gabrieli. The neural basis of visual skill learning: an fMRI study of mirror reading. Cerebral Cortex 8(1):1-10, 1998. PMID: 9510380. WOBIB: 15.

+6: 0.48060 Marcus E. Raichle; A. M. MacLeod; A. Z. Snyder; W. J. Powers; D. A. Gusnard; Gordon L. Shulman. A default mode of brain function. Proc Natl Acad Sci U S A 98(2):676-82, 2001. PMID: 11209064. DOI: 10.1073/pnas.98.2.676. WOBIB: 55.

+7: 0.44169 Andrea Mechelli; Karl J. Friston; Cathy J. Price. The effects of presentation rate during word and pseudoword reading: a comparison of PET and fMRI. Journal of Cognitive Neuroscience 12 Suppl 2():145-156, 2000. PMID: 11506654. DOI: 10.1162/089892900564000. FMRIDCID: 2-2000-11189. WOBIB: 129.

+8: 0.43996 Christian Gerlach; C. T. Aaside; G. W. Humphreys; Anders Gade; O. B. Paulson; I. Law. Brain activity related to integrative processes in visual object recognition: bottom-up integration and the modulatory influence of stored knowledge. Neuropsychologia 40(8):1254-67, 2002. PMID: 11931928. WOBIB: 7.

+9: 0.42645 Troels W. Kjaer; Ian Law; Gordon Wiltschiotz; Olaf B. Paulson; Peter L. Madsen. Regional cerebral blood flow during light sleep--a H(2)(15)O-PET study. Journal of Sleep Research 11(3):201-207, 2002. PMID: 12220315. WOBIB: 124.

+10: 0.42592 Christian Büchel; Oliver Josephs; Geraint Rees; R. Turner; C. D. Frith; Karl J. Friston. The functional anatomy of attention to visual motion. A functional MRI study. Brain 121 ( Pt 7):1281-94, 1998. PMID: 9679780. WOBIB: 24.

+11: 0.42505 Andreas Bartels; Semir Zeki. Functional brain mapping during free viewing of natural scenes. Human Brain Mapping 21(2):75-85, 2004. PMID: 14755595. DOI: 10.1002/hbm.10153. WOBIB: 123.

+12: 0.42038 Semir Zeki; R. J. Perry; A. Bartels. The processing of kinetic contours in the brain. Cerebral Cortex 13(2):189-202, 2003. PMID: 12507950. WOBIB: 52.

+13: 0.38828 E. Grossman; M. Donnelly; R. Price; D. Pickens; V. Morgan; G. Neighbor; R. Blake. Brain areas involved in perception of biological motion. Journal of Cognitive Neuroscience 12(5):711-20, 2000. PMID: 11054914. WOBIB: 33.

+14: 0.38042 Claus Bundesen; Axel Larsen; Soren Kyllingsbaek; Olaf B. Paulson; Ian Law. Attentional effects in the visual pathways: a whole-brain PET study. Experimental Brain Research 147(3):394-406, 2002. PMID: 12428147. DOI: 10.1007/s00221-002-1243-1. WOBIB: 81.

+15: 0.35048 U. Hasson; T. Hendler; D. Ben Bashat; R. Malach. Vase or face? A neural correlate of shape-selective grouping processes in the human brain. Journal of Cognitive Neuroscience 13(6):744-53, 2001. PMID: 11564319. DOI: 10.1162/08989290152541412. FMRIDCID: 2-2001-111P8. WOBIB: 36.

+16: 0.34838 Katharina Henke; Christian R. A. Mondadori; Valerie Treyer; Roger M. Nitsch; Alfred Buck; Christoph Hock. Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia 41(8):863-876, 2003. PMID: 12667523. FMRIDCID: . WOBIB: 152.

+17: 0.33803 Gemma A. Calvert; Michael J. Brammer; Edward T. Bullmore; Ruth Campbell; S. D. Iversen; Anthony S. David. Response amplification in sensory-specific cortices during crossmodal binding. NeuroReport 10(12):2619-2623, 1999. PMID: 10574380. FMRIDCID: . WOBIB: 164.

+18: 0.33375 S. Aalto; P. Naatanen; E. Wallius; L. Metsahonkala; H. Stenman; P. M. Niem; H. Karlsson. Neuroanatomical substrata of amusement and sadness: a PET activation study using film stimuli. NeuroReport 13(1):67-73, 2002. PMID: 11924897. WOBIB: 88.

+19: 0.32819 B. J. Casey; Jonathan D. Cohen; K. O'Craven; Richard J. Davidson; W. Irwin; C. A. Nelson; D. C. Noll; X. Hu; M. J. Lowe; B. R. Rosen; C. L. Truwitt; P. A. Turski. Reproducibility of fMRI results across four institutions using a spatial working memory task. NeuroImage 8(3):249-261, 1998. PMID: 9758739. FMRIDCID: . WOBIB: 116.

+20: 0.32480 Gene E. Alexander; Kewei Chen; Pietro Pietrini; Stanley I. Rapoport; Eric M. Reiman. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies. American Journal of Psychiatry 159(5):738-45, 2002. PMID: 11986126. WOBIB: 91.

+21: 0.32476 J. D. Bremner; R. B. Innis; T. White; M. Fujita; D. Silbersweig; A. W. Goddard; L. Staib; E. Stern; A. Cappiello; S. Woods; R. Baldwin; D. S. Charney. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 47(2):96-106, 2000. PMID: 10664825. WOBIB: 126.

+22: 0.32047 F. Lacquaniti; Daniela Perani; E. Guigon; V. Bettinardi; M. Carrozzo; F. Grassi; Yves Rossetti; F. Fazio. Visuomotor Transformations for Reaching to Memorized Targets: A PET study. NeuroImage 5(2):129-146, 1997. PMID: 9345543. DOI: 10.1006.nimg.1996.0254. FMRIDCID: . WOBIB: 182.

+23: 0.31755 J. M. Ellermann; J. D. Siegal; J. P. Strupp; T. J. Ebner; K. Ugurbil. Activation of visuomotor systems during visually guided movements: a functional MRI study. Journal of Magnetic Resonance 131(2):272-285, 1998. PMID: 9571103. WOBIB: 45.

+24: 0.30199 Mary L. Phillips; E. T. Bullmore; R. Howard; P. W. Woodruff; I. C. Wright; Steven C. R. Williams; A. Simmons; C. Andrew; M. Brammer; Anthony S. David. Investigation of facial recognition memory and happy and sad facial expression perception: an fMRI study. Psychiatry Research 83(3):127-38, 1998. PMID: 9849722. WOBIB: 98.

+25: 0.29390 Rosa Maria Moresco; M. Dieci; A. Vita; Christina Messa; C. Gobbo; L. Galli; Giovanna Rizzo; A. Panzacchi; L. De Peri; G. Invernizzi; Ferruchio Fazio. In vivo serotonin 5HT(2A) receptor binding and personality traits in healthy subjects: a positron emission tomography study. NeuroImage 17(3):1470-1478, 2002. PMID: 12414286. FMRIDCID: . WOBIB: 161.

Antirelated - negatively correlated volumes

-1: 0.00000 J. D. Bremner; R. B. Innis; S. M. Southwick; L. Staib; S. Zoghbi; D. S. Charney. Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder. American Journal of Psychiatry 157(7):1120-1126, 2000. PMID: 10873921. WOBIB: 67.

-2: 0.00000 E. A. Phelps; F. Hyder; A. M. Blamire; R. G. Shulman. FMRI of the prefrontal cortex during overt verbal fluency. NeuroReport 8(2):561-5, 1997. PMID: 9080448. WOBIB: 12.

-3: 0.00000 Christian Gerlach; I. Law; Anders Gade; O. B. Paulson. The role of action knowledge in the comprehension of artefacts--a PET study. NeuroImage 15(1):143-52, 2002. PMID: 11771982. DOI: 10.1006/nimg.2002.0969. WOBIB: 34.

-4: 0.00000 Wai Ting Soik; Zhen Jin; Paul Fletcher; Li Hai Tan. Distinct brain regions associated with syllable and phoneme. Human Brain Mapping 18(3):201-207, 2003. PMID: 12599278. DOI: 10.1002/hbm.10094. FMRIDCID: . WOBIB: 172.

-5: 0.00000 F. Hyder; E. A. Phelps; C. J. Wiggins; K. S. Labar; A. M. Blamire; R. G. Shulman. "Willed action": a functional MRI study of the human prefrontal cortex during a sensorimotor task. Proc Natl Acad Sci U S A 94(13):6989-6994, 1997. PMID: 9192679. WOBIB: 6.

Bib -> Asymmetry | Author | ICA | NMF | Novelty | Statistics | SVD | Title | WOBIB ]
Exp -> Alphabetic | Asymmetry | ICA | NMF | Novelty | SVD | WOEXP | WOEXT ]
Ext -> Alphabetic index | Map | Roots ]          [ Brede ]          Loc -> Statistics ]
Automatically constructed by Brede Toolbox through brede_bib_bib2html, 2006-08-15T20:35:22